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公开(公告)号：US20170218095A1
公开(公告)日：2017-08-03
申请号：US15453750
申请日：2017-03-08
Applicant: LIFE TECHNOLOGIES AS
Inventor： Grete MODAHL , Geir FONNUM , Astrid MOLTEBERG , Silje LIEN , Nini KJUS
CPC classification number: C08F2/22 , C08F8/30 , C08F12/08 , C08F212/36 , C08F257/02 , C08F2800/20 , C08J3/128 , C08J9/18 , C08J9/20 , C08J2325/08 , C12N11/08 , Y10T428/2982 , Y10T428/2991 , Y10T428/2998 , C08F212/08
Abstract: This invention relates to monodisperse cross-linked polymer particles, comprising particles with a substantially smooth outer surface and an average diameter of less than 1 μm, wherein the particles are solid or porous, and wherein the coefficient of variation (CV) % of the particles, when measured by CPS disk centrifugation analysis, is less than 15%. These monodisperse cross-linked polymer particles may comprise magnetic material and are useful in various application. This invention also relates to monodisperse polymer particles for use as seed particles in the Ugelstad process.
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公开(公告)号：US20170002152A1
公开(公告)日：2017-01-05
申请号：US15200533
申请日：2016-07-01
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir FONNUM , Steven M. MENCHEN , Talha M. GOKMEN , Pontus LUNDBERG , Prasanna Krishnan THWAR , Alfred LUI , Lily LU , Wolfgang HINZ , Lene HUSABOE , Elisabeth BREIVOLD , Astrid Evenroed MOLTEBERG , Synne LARSEN
IPC: C08J3/075 , C08F220/70
CPC classification number: C08J3/075 , C08F8/12 , C08F220/58 , C08F220/70 , C08F2230/085 , C08J2333/26 , C08F222/38
Abstract: A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.
Abstract translation: 聚合物基材如聚合物颗粒由羧基官能单体形成。 在一个实例中，羧基官能单体具有保护基代替羧基的OH。 一旦单体聚合，就可以除去这种保护基团，从而提供具有羧基官能位点的聚合物网络。 这种位点可用于将其它功能性附加到聚合物基材上。
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公开(公告)号：US20160137762A1
公开(公告)日：2016-05-19
申请号：US15005420
申请日：2016-01-25
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir FONNUM , Grete Irene MODAHL , Nini Hofsloekken KJUS , Astrid Evenroed MOLTEBERG , Diem Thuy Thi TRAN , Jo AASERUD , M. Talha GOKMEN , Steven M. MENCHEN , Carl FULLER , Luisa ANDRUZZI , Wolfgang HINZ
IPC: C08F130/08 , C08F6/24 , C08J9/20
CPC classification number: C08F130/08 , C07F7/1804 , C07F7/188 , C08F2/20 , C08F2/26 , C08F6/24 , C08F8/12 , C08F8/32 , C08F8/34 , C08F220/58 , C08F222/385 , C08F230/08 , C08F2800/20 , C08J9/20 , C08J2343/04 , C12P19/34 , C12Q1/686 , C12Q1/6874 , G01N27/4145 , Y10T428/2982 , C08F257/02 , C08F2222/1013 , C08F212/36 , C08F220/60 , C12Q2563/149 , C12Q2563/159 , C12Q2565/543
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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公开(公告)号：US20160097095A1
公开(公告)日：2016-04-07
申请号：US14970241
申请日：2015-12-15
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir FONNUM , Grete Irene MODAHL , Nini Hofslokken KJUS , Astrid Evenroed MOLTEBERG , Diem TRAN , Jo AASERUD , Talha M. GOKMEN , Steven M. MENCHEN , Carl FULLER , Luisa ANDRUZZI , Wolfgang HINZ
IPC: C12Q1/68 , G01N27/414
CPC classification number: C08F130/08 , C07F7/1804 , C07F7/188 , C08F2/20 , C08F2/26 , C08F6/24 , C08F8/12 , C08F8/32 , C08F8/34 , C08F220/58 , C08F222/385 , C08F230/08 , C08F2800/20 , C08J9/20 , C08J2343/04 , C12P19/34 , C12Q1/686 , C12Q1/6874 , G01N27/4145 , Y10T428/2982 , C08F257/02 , C08F2222/1013 , C08F212/36 , C08F220/60 , C12Q2563/149 , C12Q2563/159 , C12Q2565/543
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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公开(公告)号：US20230322996A1
公开(公告)日：2023-10-12
申请号：US18053066
申请日：2022-11-07
Applicant: LIFE TECHNOLOGIES AS
Inventor： Huey Wen OOI , Pontus LUNDBERG , Maxi-Lu BOESCHEN , Hilde ALMAASBAK , Tuva Holt HERENG , Tor Espen STAV-NORAAS , Ole LANDSVERK , Geir FONNUM
IPC: C08F283/04
CPC classification number: C08F283/04
Abstract: The invention relates to polymer-interaction molecule (e.g., antibodies) conjugates and uses of such conjugates for delivery of interaction molecules to cells. The invention also relates uses polymer-interaction molecule (e.g., antibodies) conjugates for eliciting cellular responses (e.g., induction of cell proliferation).
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Patent Agency Ranking
公开(公告)号：US20170306072A1
公开(公告)日：2017-10-26
申请号：US15647052
申请日：2017-07-11
Applicant: LIFE TECHNOLOGIES AS
Inventor： Geir FONNUM , Lise LILJEROTH
IPC: C08F293/00 , C08F287/00 , C08L53/00 , C09D153/00
CPC classification number: C08F293/00 , C08F287/00 , C08F292/00 , C08F293/005 , C08F2438/01 , C08L53/005 , C09D153/005 , C08L2666/02
Abstract: Polymer particles having a multi-block vinylic polymer attached to their surface are disclosed. The particles can be used in a variety of purification and detection methods.
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公开(公告)号：US20150284496A1
公开(公告)日：2015-10-08
申请号：US14745815
申请日：2015-06-22
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Nini Hofslokken KJUS , Geir FONNUM , Bruce BRANCHAUD , Lai-Qiang YING , Steven M. MENCHEN , Dmitriy GREMYACHINSKIY , Hee Chol KANG
IPC: C08F230/08
CPC classification number: C08F230/08 , C07F7/10 , C07F7/1804 , C08F220/58 , C08F222/385 , C08F236/20 , C08K3/20
Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
Abstract translation: 描述了甲硅烷基保护的二丙烯酰胺化合物。 形成这种化合物的方法包括在第一反应条件下将甲硅烷基化试剂与羟基化二胺化合物混合以在第一溶液中形成产物，将产物与第一溶液分离，并在第二反应条件下将产物与丙烯酰氯混合 形成甲硅烷基保护的二丙烯酰胺化合物的第二溶液。
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公开(公告)号：US20140142254A1
公开(公告)日：2014-05-22
申请号：US14082368
申请日：2013-11-18
Applicant: LIFE TECHNOLOGIES AS , LIFE TECHNOLOGIES CORPORATION
Inventor： Geir FONNUM , Grete I. MODAHL , Nini H. KJUS , Astrid E. MOLTEBERG , Diem TRAN , Jo AASERUD , Talha M. GOKMEN , Steven M. MENCHEN , Carl FULLER , Luisa ANDRUZZI , Wolfgang HINZ
CPC classification number: C08F130/08 , C07F7/1804 , C07F7/188 , C08F2/20 , C08F2/26 , C08F6/24 , C08F8/12 , C08F8/32 , C08F8/34 , C08F220/58 , C08F222/385 , C08F230/08 , C08F2800/20 , C08J9/20 , C08J2343/04 , C12P19/34 , C12Q1/686 , C12Q1/6874 , G01N27/4145 , Y10T428/2982 , C08F257/02 , C08F2222/1013 , C08F212/36 , C08F220/60 , C12Q2563/149 , C12Q2563/159 , C12Q2565/543
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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公开(公告)号：US20140073715A1
公开(公告)日：2014-03-13
申请号：US14082419
申请日：2013-11-18
Applicant: LIFE TECHNOLOGIES AS , LIFE TECHNOLOGIES CORPORATION
Inventor： Geir FONNUM , Grete I. MODAHL , Nini H. KJUS , Astrid E. MOLTEBERG , Diem TRAN , Jo AASERUD , Talha M. GOKMEN , Steven M. MENCHEN , Carl FULLER , Luisa ANDRUZZI , Wolfgang HINZ
IPC: C08F222/38
CPC classification number: C08F130/08 , C07F7/1804 , C07F7/188 , C08F2/20 , C08F2/26 , C08F6/24 , C08F8/12 , C08F8/32 , C08F8/34 , C08F220/58 , C08F222/385 , C08F230/08 , C08F2800/20 , C08J9/20 , C08J2343/04 , C12P19/34 , C12Q1/686 , C12Q1/6874 , G01N27/4145 , Y10T428/2982 , C08F257/02 , C08F2222/1013 , C08F212/36 , C08F220/60 , C12Q2563/149 , C12Q2563/159 , C12Q2565/543
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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公开(公告)号：US20230167210A1
公开(公告)日：2023-06-01
申请号：US18101785
申请日：2023-01-26
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir FONNUM , Grete Irene MODAHL , Nini Hofsloekken KJUS , Astrid Evenroed MOLTEBERG , Diem Thuy Thi TRAN , Jo AASERUD , M. Talha GOKMEN , Steven M. MENCHEN , Carl FULLER , Luisa ANDRUZZI , Wolfgang HINZ
IPC: C08F130/08 , C07F7/18 , C08F8/12 , C12Q1/686 , C08F2/20 , C08F2/26 , C08F230/08 , C08F6/24 , C08F222/38 , C08F8/32 , C08F8/34 , C12P19/34 , C12Q1/6874 , G01N27/414 , C08J9/20
CPC classification number: C08F130/08 , C07F7/1804 , C08F8/12 , C12Q1/686 , C07F7/188 , C08F2/20 , C08F2/26 , C08F230/085 , C08F6/24 , C08F222/385 , C08F8/32 , C08F8/34 , C12P19/34 , C12Q1/6874 , G01N27/4145 , C08J9/20 , Y10T428/2982 , C08F2800/20 , C08F220/603
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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