公开(公告)号：US09988622B2

公开(公告)日：2018-06-05

申请号：US14697962

申请日：2015-04-28

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Kevin Hacker ,  Gregory Govoni ,  Nikolay Sergeev ,  Elena Bolchakova ,  Maxim Brevnov ,  Manohar Furtado ,  Johnie Young ,  James Nurse ,  Mariela Cuadras

IPC: C12N15/10 ,  C12Q1/68 ,  G01N21/75 ,  C12N1/06 ,  B01D29/13

CPC classification number: C12N15/1003 ,  B01D29/13 ,  C12N1/066 ,  C12Q1/68 ,  C12Q1/689 ,  C12Q1/6895 ,  G01N21/75

Abstract: Devices and methods for detecting microbial contaminants, such as bacteria and fungi, in fluids such as drinking water, pharmaceutical solutions and tissue culture media are provided. More particularly, provided are filtration devices for capture and processing of microorganisms from fluids, and improved methods for recovery, lysis and detection of microorganisms based on a combination of physical disruption with small beads and lysis solutions.

公开(公告)号：US10994275B2

公开(公告)日：2021-05-04

申请号：US16291757

申请日：2019-03-04

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael Pallas ,  Evan Foster ,  Jorge Fonseca ,  James Nurse ,  Theodore Straub

IPC: B01L3/00 ,  B01L7/00 ,  B01L9/00 ,  C12Q1/686 ,  G01N21/64

Abstract: A system for processing a plurality of biological samples contains a support and a temperature controller. The suppose is configured to hold a case that includes an inner chamber and a substrate located within the inner chamber, the substrate containing a plurality of isolated reaction sites containing one or more biological samples. The temperature controller is configured to maintain or control a temperature of at least one of the support, the case, or the one or more biological samples during an assay or reaction on the one or more biological samples. The support is also configured to maintain at least one of the surfaces of substrate at a positive angle relative to a horizontal plane during the assay or reaction.

公开(公告)号：US10252272B2

公开(公告)日：2019-04-09

申请号：US14893356

申请日：2014-05-27

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael Pallas ,  Evan Foster ,  Jorge Fonseca ,  James Nurse ,  Theodore Straub

IPC: B01L3/00 ,  B01L7/00 ,  B01L9/00 ,  C12Q1/686 ,  G01N21/64

Abstract: A system for processing a plurality of biological samples contains a support and a temperature controller. The support is configured to hold a case that includes an inner chamber and a substrate located within the inner chamber, the substrate containing a plurality of isolated reaction sites containing one or more biological samples. The temperature controller is configured to maintain or control a temperature of at least one of the support, the case, or the one or more biological samples during an assay or reaction on the one or more biological samples. The support is also configured to maintain at least one of the surfaces of substrate at a positive angle relative to a horizontal plane during the assay or reaction.