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1.发明申请公开(公告)号：US20190217261A1
公开(公告)日：2019-07-18
申请号：US16238618
申请日：2019-01-03
发明人： Nephi Jones , Steven KJAR , Brycen MILLS , Mark SMITH , Derik WEST
CPC分类号： B01F7/00391 , B01F3/04531 , B01F7/0005 , B01F7/00725 , B01F7/24 , B01F15/00538 , B01F15/00707 , B01F15/0085 , B01F2003/04673 , B01F2015/0011 , B01F2015/00603 , B01F2215/0073 , C12M23/58 , C12M27/02 , C12M27/06 , C12M35/04 , C12N5/0602 , C12N2527/00
摘要： The present set of embodiments relate to a bioproduction system, method, and apparatus for mixing a fluid. The bioproduction mixing system includes an offset helical assembly having a stabilizer and impeller for mixing a fluid within a flexible compartment The bioproduction mixing system is designed for efficient mixing of the fluid and for use with a variety of different impellers that can be located at different locations according to the volume and shape characteristics of the flexible compartment. The bioproduction mixing system is optimized to eliminate stagnation zones while maximizing bulk fluid flow.
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公开(公告)号：US20190218496A1
公开(公告)日：2019-07-18
申请号：US16238591
申请日：2019-01-03
发明人： Christopher Brau , Nephi JONES , Mark SMITH
CPC分类号： B01F7/00391 , B01F3/04531 , B01F7/0005 , B01F7/00725 , B01F7/24 , B01F15/00538 , B01F15/00707 , B01F15/0085 , B01F2003/04673 , B01F2015/0011 , B01F2015/00603 , B01F2215/0073 , C12M23/58 , C12M27/02 , C12M27/06 , C12M35/04 , C12N5/0602 , C12N2527/00
摘要： The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.
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公开(公告)号：US20190218494A1
公开(公告)日：2019-07-18
申请号：US16238656
申请日：2019-01-03
发明人： Nephi Jones , Steven KJAR , Daniel PRICE , Mark SMITH , Paul THACKER
CPC分类号： B01F7/00391 , B01F3/04531 , B01F7/0005 , B01F7/00725 , B01F7/24 , B01F15/00538 , B01F15/00707 , B01F15/0085 , B01F2003/04673 , B01F2015/0011 , B01F2015/00603 , B01F2215/0073 , C12M23/58 , C12M27/02 , C12M27/06 , C12M35/04 , C12N5/0602 , C12N2527/00
摘要： The present set of embodiments relate a system, method, and various devices for installation of a bioproduction system. The bioproduction system includes a rigid housing having a moveable platform to assist in the installation of a bioprocessing container within. The system also includes mounting systems for a variety of peripherals originating from the flexible container while safeguarding operators. More specifically, the system includes systems and methods for mounting bearings, organizing tube sets, and placement of the flexible container in its proper orientation.
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