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公开(公告)号：US10081787B2
公开(公告)日：2018-09-25
申请号：US15276681
申请日：2016-09-26
申请人： PBS Biotech, Inc.
发明人： J. Gregory Zeikus
IPC分类号： C12M1/00 , C12M1/06 , C12M1/09 , C12M1/12 , B01F3/04 , B01F7/00 , B01F7/04 , B01F7/22 , C12M1/02 , C12M1/34
CPC分类号： C12M27/06 , B01F3/04531 , B01F7/00183 , B01F7/00308 , B01F7/00916 , B01F7/04 , B01F7/22 , B01F2003/04631 , B01F2003/04673 , C12M23/28 , C12M23/56 , C12M27/00 , C12M37/00 , C12M41/12 , C12M41/42
摘要： A pneumatic bioreactor includes a vessel containing a fluid to be mixed and at least one mixing device driven by gas pressure. A first embodiment includes a floating impeller that rises and falls in the fluid as gas bubbles carry it upward to the surface where the gas is then vented, permitting the impeller to sink in the fluid. The floating impeller may be tethered to a second impeller with a flexible member and pulley. The mixing speed is controlled with electromagnets in the vessel acting upon magnetic material in the impeller or its guides. In another embodiment, floating pistons mix the fluid, pushing it through a mixing plate with one or more apertures. In a third embodiment, the mixing device is a rotating drum with bubble-catching blades and rotating mixing plates with apertures. The top of the vessel for these mixers may include a closed top and sterile filters.
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公开(公告)号：US20180184626A1
公开(公告)日：2018-07-05
申请号：US15738273
申请日：2017-01-25
发明人： Young June MOON , Dae Han KIM
CPC分类号： A01K63/042 , A01K63/04 , B01F3/04 , B01F3/04531 , B01F7/00 , B01F7/00341 , B01F7/06 , B01F2215/0052 , C02F1/40 , C02F1/74 , C02F3/12 , C02F3/20 , C02F7/00 , C02F2103/20 , F04D7/045 , F04D31/00
摘要： A contra-rotating multi-layer propeller unit for multi-phase flow according to an exemplary embodiment of the present disclosure includes: a shaft part; a front propeller and a rear propeller connected to the shaft part; an air collection part including a predetermined space therein and the shaft part positioned in the internal space; and an air supply pipe configured to supply air into the air collection part, and a rear propeller blade includes a two-phase blade connected to a rear propeller hub, a layer structure of which an inner surface is connected to an end portion of the two-phase blade, and a single-phase blade positioned at a location corresponding to the two-phase blade on an outer surface of the layer structure.
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公开(公告)号：US20180050940A1
公开(公告)日：2018-02-22
申请号：US15381888
申请日：2016-12-16
发明人： Yong Joo Park , Sun Wan Hwang , Jung Goo Myoung , Jang Geun Lim
CPC分类号： C02F1/76 , A01K63/045 , B01F3/04531 , B01F7/00208 , B01F7/003 , B01F7/0035 , B01F7/004 , B01F7/00416 , B01F7/00425 , B01F7/00566 , B01F7/00633 , B01F7/00908 , B01F7/00916 , B01F7/048 , B01F7/086 , B01F15/00883 , B01F15/065 , B01F2003/04907 , B01F2015/062 , B01F2215/0052 , B63J4/002 , C02F1/004 , C02F2103/008 , C02F2103/20 , C02F2209/29 , C02F2303/04
摘要： The ballast water and fish farm treatment system for circulating effluent water of a fish farm or a ship by filtering and resupplying the effluent water, the system including a heat exchange system to heat or cool the effluent water, a physical filtration unit to filter out impurities from the effluent water are discharged from the heat exchange system, and a chemical filtration unit to mix the effluent water discharged from the physical filtration unit with chlorine dioxide, wherein the effluent water discharged from the chemical filtration unit is resupplied to the fish farm or the ship. The ballast water and fish farm treatment system allows circulation water of the ship and fish farm to be reused after completely removing parasites, hazardous organisms, germs, and viruses from the circulation water using a combination of physical, chemical and physiological treatment techniques.
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公开(公告)号：US20170233505A1
公开(公告)日：2017-08-17
申请号：US15502376
申请日：2015-08-06
发明人： Reinhard KUEHL , Harald PRANG , Rodrigo CARVAJAL , Elke DAMM , Phil PYMAN
CPC分类号： C08F10/02 , B01F3/04531 , B01F7/00633 , B01F7/22 , B01F2215/0422 , B01F2215/0431 , B01F2215/0481 , B01J4/002 , B01J8/224 , B01J8/226 , B01J19/0066 , B01J19/18 , B01J19/1875 , B01J2208/00902 , C08F2/01 , C08F2/18
摘要： The present disclosure relates to a process for the preparation of polyethylene by polymerizing in a slurry ethylene and optionally one or more C3 to C10 alpha-olefins. In some embodiments, the polymerization is carried out in a cylindrical polymerization reactor equipped with an agitator for mixing the contents of the reactor and inducing a flow of the slurry, the ethylene is fed into the reactor by an ethylene injection system comprising one or more injection nozzles which project through the bottom reactor head or through the reactor wall and extend from 0.02-0.5 times the inner diameter D into the reactor, and the ethylene exits the injection nozzle with an exit velocity from 10-200 m/s.
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公开(公告)号：US20170009193A1
公开(公告)日：2017-01-12
申请号：US15276681
申请日：2016-09-26
申请人： PBS Biotech, Inc.
发明人： J. Gregory Zeikus
CPC分类号： C12M27/06 , B01F3/04531 , B01F7/00183 , B01F7/00308 , B01F7/00916 , B01F7/04 , B01F7/22 , B01F2003/04631 , B01F2003/04673 , C12M23/28 , C12M23/56 , C12M27/00 , C12M37/00 , C12M41/12 , C12M41/42
摘要： A pneumatic bioreactor includes a vessel containing a fluid to be mixed and at least one mixing device driven by gas pressure. A first embodiment includes a floating impeller that rises and falls in the fluid as gas bubbles carry it upward to the surface where the gas is then vented, permitting the impeller to sink in the fluid. The floating impeller may be tethered to a second impeller with a flexible member and pulley. The mixing speed is controlled with electromagnets in the vessel acting upon magnetic material in the impeller or its guides. In another embodiment, floating pistons mix the fluid, pushing it through a mixing plate with one or more apertures. In a third embodiment, the mixing device is a rotating drum with bubble-catching blades and rotating mixing plates with apertures. The top of the vessel for these mixers may include a closed top and sterile filters.
摘要翻译： 气动生物反应器包括容纳待混合的流体的容器和由气体压力驱动的至少一个混合装置。 第一实施例包括浮动叶轮，其随着气泡将其向上运送到气体然后被排出的表面而上升和下降，允许叶轮沉入流体中。 浮动叶轮可以用柔性构件和滑轮系在第二叶轮上。 混合速度由容器中的电磁体控制，作用在叶轮或其引导件中的磁性材料上。 在另一个实施例中，浮动活塞将流体混合，将其推入具有一个或多个孔的混合板。 在第三实施例中，混合装置是具有吸泡叶片的旋转鼓和具有孔的旋转混合板。 用于这些混合器的容器的顶部可以包括封闭的顶部和无菌过滤器。
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6.发明授权Ionic aqueous solutions comprising charge-stabilized oxygen-containing nanobubbles 有权包含电荷稳定的含氧纳米气泡的离子水溶液公开(公告)号：US09511333B2
公开(公告)日：2016-12-06
申请号：US13851888
申请日：2013-03-27
CPC分类号： B01F5/0665 , A23L2/54 , A61J3/00 , A61K9/08 , A61K9/10 , A61K33/00 , B01F3/04099 , B01F3/04531 , B01F3/0807 , B01F3/0853 , B01F7/008 , B01F7/00816 , C02F1/727 , C02F3/02 , C09K3/00 , C12M27/00 , Y02W10/15
摘要： Provided are electrokinetically-altered fluids (e.g., gas-enriched (e.g., oxygen-enriched) electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized oxygen-containing nanostructures in an amount sufficient to provide, upon contact with a cell, modulation of at least one of cellular membrane potential and cellular membrane conductivity. Further provided are the methods of making the electrokinetically-altered ionic aqueous fluid compositions. Particular aspects provide for regulating or modulating intracellular signal transduction associated by modulation of at least one of cellular membranes, membrane potential, membrane proteins such as membrane receptors, including but not limited to G-Protein Coupled Receptors (GPCR), and intercellular junctions (e.g., tight junctions, gap junctions, zona adherins and desmasomes). Other embodiments include particular methods of producing the electrokinetically-altered fluids. The electrokinetically-altered fluid compositions and methods of producing the fluid include electrokinetically-altered ionic aqueous fluids optionally in the form of solvated electrons stabilized with molecular oxygen.
摘要翻译： 提供了电动改变的流体（例如，富含气体（例如富氧）电动流体），其包含电荷稳定的含氧纳米结构的离子水溶液，其量足以在与电池接触时提供调制 细胞膜电位和细胞膜电导率中的至少一种。 进一步提供制备电动改性的离子水性液体组合物的方法。 特定方面提供调节或调节与细胞膜，膜电位，膜蛋白如膜受体（包括但不限于G蛋白偶联受体（GPCR））和细胞间结合（例如，细胞间接合）中的至少一种调节相关的细胞内信号转导。 ，紧密连接处，间隙连接处，扎胶粘合剂和粘胶）。 其它实施方案包括产生电动改变的流体的特定方法。 电动改变的流体组合物和制备流体的方法包括任选地以分子氧稳定的溶剂化电子的形式的电动改变的离子水性流体。
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公开(公告)号：US09453194B2
公开(公告)日：2016-09-27
申请号：US14444695
申请日：2014-07-28
申请人： PBS Biotech, Inc.
发明人： J. Gregory Zeikus
IPC分类号： C12N1/12 , A01G7/00 , C12M1/00 , B01F3/04 , B01F7/00 , B01F7/04 , B01F7/22 , C12M1/09 , C12M1/02 , C12M1/06 , C12M1/12 , C12M1/34
CPC分类号： C12M27/06 , B01F3/04531 , B01F7/00183 , B01F7/00308 , B01F7/00916 , B01F7/04 , B01F7/22 , B01F2003/04631 , B01F2003/04673 , C12M23/28 , C12M23/56 , C12M27/00 , C12M37/00 , C12M41/12 , C12M41/42
摘要： A pneumatic bioreactor includes a vessel containing a fluid to be mixed and at least one mixing device driven by gas pressure. A first embodiment includes a floating impeller that rises and falls in the fluid as gas bubbles carry it upward to the surface where the gas is then vented, permitting the impeller to sink in the fluid. The floating impeller may be tethered to a second impeller with a flexible member and pulley. The mixing speed is controlled with electromagnets in the vessel acting upon magnetic material in the impeller or its guides. In another embodiment, floating pistons mix the fluid, pushing it through a mixing plate with one or more apertures. In a third embodiment, the mixing device is a rotating drum with bubble-catching blades and rotating mixing plates with apertures. The top of the vessel for these mixers may include a closed top and sterile filters.
摘要翻译： 气动生物反应器包括容纳待混合的流体的容器和由气体压力驱动的至少一个混合装置。 第一实施例包括浮动叶轮，其随着气泡将其向上运送到气体然后被排出的表面而上升和下降，允许叶轮沉入流体中。 浮动叶轮可以用柔性构件和滑轮系在第二叶轮上。 混合速度由容器中的电磁体控制，作用在叶轮或其引导件中的磁性材料上。 在另一个实施例中，浮动活塞将流体混合，将其推入具有一个或多个孔的混合板。 在第三实施例中，混合装置是具有吸泡叶片的旋转鼓和具有孔的旋转混合板。 用于这些混合器的容器的顶部可以包括封闭的顶部和无菌过滤器。
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公开(公告)号：US09388375B2
公开(公告)日：2016-07-12
申请号：US14395728
申请日：2013-03-15
IPC分类号： C12M1/04 , C12M1/00 , B01F13/02 , B01F3/04 , C12M1/02 , C12M1/34 , B01F7/22 , B01F15/00 , B01F11/00
CPC分类号： C12M29/06 , B01F3/04439 , B01F3/0446 , B01F3/04531 , B01F7/22 , B01F11/0002 , B01F11/0082 , B01F13/0205 , B01F13/0211 , B01F13/0272 , B01F15/0085 , B01F2003/04879 , B01F2003/04943 , B01F2215/0073 , C12M23/00 , C12M23/14 , C12M23/26 , C12M27/00 , C12M27/02 , C12M29/14 , C12M41/34
摘要： A method and system for achieving a gas-liquid mass transfer includes delivering into a compartment of a container a liquid, the liquid having an exposed top surface disposed within the compartment. A stream of a gas is passed over the top surface of the liquid so that the stream of gas produces turbulence on the top surface that is sufficient to achieve the gas-liquid mass transfer. In one embodiment the liquid is a culture that includes cells or microorganisms and the mass transfer functions to oxygenate the culture sufficient to sustain the cells or microorganisms.
摘要翻译： 用于实现气 - 液传质的方法和系统包括将液体输送到容器的隔室中，液体具有设置在隔室内的暴露的顶表面。 气体流通过液体的顶表面，使得气流在顶表面上产生足以实现气 - 液传质的湍流。 在一个实施方案中，液体是包含细胞或微生物的培养物，并且传质功能使培养物充氧足以维持细胞或微生物。
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公开(公告)号：US09314751B2
公开(公告)日：2016-04-19
申请号：US12986701
申请日：2011-01-07
IPC分类号： B01F7/00 , B01F7/16 , B01F3/04 , B01F7/22 , B01F13/00 , B01F15/00 , C12M1/00 , C12M1/06 , B65B3/04
CPC分类号： B65B1/02 , B01F3/04262 , B01F3/04269 , B01F3/04531 , B01F7/00 , B01F7/00033 , B01F7/00208 , B01F7/00691 , B01F7/00725 , B01F7/1695 , B01F7/22 , B01F13/0032 , B01F15/00006 , B01F15/0072 , B01F15/00785 , B01F15/0085 , B01F2215/0431 , B65B3/045 , C12M23/26 , C12M27/02 , C12M29/06
摘要： A method for mixing includes releasably coupling a first container station to a docking station, the first container station having a shipping vessel bounding a compartment, the docking station having a stand and a drive motor assembly adjustably mounted to the stand. The vertical or horizontal position of the drive motor assembly is adjusted relative to the stand so that the drive motor assembly is in a first position. A drive shaft is advanced through the drive motor assembly and into a chamber of a first collapsible bag disposed within the compartment of the shipping vessel. The drive motor assembly is activated so that the mixer rotates the drive shaft causing mixing of the fluid within the first collapsible bag.
摘要翻译： 一种用于混合的方法包括将第一容器站可拆卸地连接到对接站，第一容器站具有围绕隔室的运输船，对接站具有支架和可调节地安装到支架的驱动马达组件。 驱动马达组件的垂直或水平位置相对于支架进行调整，使得驱动马达组件处于第一位置。 驱动轴通过驱动电动机组件前进到设置在运输船的隔室内的第一可折叠袋的室中。 驱动马达组件被启动，使得混合器旋转驱动轴，引起第一可折叠袋内的流体的混合。
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公开(公告)号：US09169113B2
公开(公告)日：2015-10-27
申请号：US14005666
申请日：2012-03-16
申请人： Enrico Grampassi
发明人： Enrico Grampassi
CPC分类号： B67D1/0406 , B01F3/04531 , B01F3/04808 , B67D1/0016 , B67D1/0043 , B67D1/0057 , B67D1/0075 , B67D1/0857 , B67D1/1234 , B67D1/125 , B67D1/1252 , B67D1/1272
摘要： The apparatus for preparing carbonated refrigerated beverages comprises at least one containment tank (2) suitable to contain the product to be dispensed and closed by a pressure tightening lid (4); means for feeding the product to be dispensed inside said containment tank (2); and means for feeding a pressurization gas inside said containment tank (2) to maintain the same tank (2) under pressure. The feed means of the pressurization gas comprise single feed and discharge ducts (21, 22) for the pressurization gas, separately connected to said tank (2) and provided with respective valve members (23, 24) for controlling the flow of the same pressurization gas.
摘要翻译： 用于制备碳酸化冷冻饮料的装置包括至少一个容纳罐（2），其适于容纳待分配的产品并通过压力紧固盖（4）封闭; 用于将待分配的产品供给到所述容纳箱（2）内的装置; 以及用于在所述容纳箱（2）内部供给加压气体以将所述罐（2）保持在压力下的装置。 加压气体的进料装置包括用于加压气体的单个进料和排出管道（21,22），分别连接到所述罐（2）并设置有相应的阀构件（23,24），用于控制相同加压的流动 加油站。
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