公开(公告)号：US10023866B2

公开(公告)日：2018-07-17

申请号：US15691721

申请日：2017-08-30

Applicant: Life Technologies Corporation

Inventor： Christopher Burnett ,  Nitin Puri ,  Susan Magdaleno ,  Alexander Vlassov

IPC: C07H21/02 ,  C07H21/04 ,  A61K31/70 ,  C12N15/113 ,  A61K31/713 ,  C12N15/11 ,  A61K47/50

Abstract: The invention relates generally to compositions and methods for inhibiting the function of target nucleic acids by sequence specific binding. The compositions and methods can be used for inhibition of micro RNAs and other relatively short non-coding RNAs.

公开(公告)号：US20170009232A1

公开(公告)日：2017-01-12

申请号：US15217007

申请日：2016-07-22

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Christopher BURNETT ,  Nitin Puri ,  Susan Magdaleno ,  Alexander Vlassov

IPC: C12N15/113 ,  A61K47/48 ,  A61K31/713

CPC classification number: C12N15/113 ,  A61K31/713 ,  A61K47/50 ,  C12N15/111 ,  C12N2310/113 ,  C12N2310/141 ,  C12N2310/321 ,  C12N2310/322 ,  C12N2310/3231 ,  C12N2310/332 ,  C12N2310/3515 ,  C12N2310/3519 ,  C12N2310/51 ,  C12N2310/531 ,  C12N2330/31

Abstract: The invention relates generally to compositions and methods for inhibiting the function of target nucleic acids by sequence specific binding. The compositions and methods can be used for inhibition of micro RNAs and other relatively short non-coding RNAs.

Abstract translation: 本发明一般涉及通过序列特异性结合抑制靶核酸功能的组合物和方法。 组合物和方法可用于抑制微RNA和其他相对较短的非编码RNA。

公开(公告)号：US12054790B2

公开(公告)日：2024-08-06

申请号：US16856036

申请日：2020-04-23

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Ioanna Pagani ,  Pius Brzoska ,  Kelly Li ,  Sunali Patel ,  Boli Huang ,  Kamini Varma ,  Nitin Puri ,  Evan Diamond

IPC: C12Q1/68 ,  C12Q1/6888 ,  C12Q1/689 ,  C12Q1/6895

CPC classification number: C12Q1/689 ,  C12Q1/6888 ,  C12Q1/6895 ,  C12Q2600/158 ,  C12Q2600/16

Abstract: Methods, compositions and kits for detecting microorganisms and/or profiling microbiota such as for example through use of nucleic acid amplification and detection.

公开(公告)号：US20180057814A1

公开(公告)日：2018-03-01

申请号：US15691721

申请日：2017-08-30

Applicant: Life Technologies Corporation

Inventor： Christopher BURNETT ,  Nitin Puri ,  Susan Magdaleno ,  Alexander Vlassov

IPC: C12N15/113 ,  A61K31/713 ,  C12N15/11

CPC classification number: C12N15/113 ,  A61K31/713 ,  A61K47/50 ,  C12N15/111 ,  C12N2310/113 ,  C12N2310/141 ,  C12N2310/321 ,  C12N2310/322 ,  C12N2310/3231 ,  C12N2310/332 ,  C12N2310/3515 ,  C12N2310/3519 ,  C12N2310/51 ,  C12N2310/531 ,  C12N2330/31

Abstract: The invention relates generally to compositions and methods for inhibiting the function of target nucleic acids by sequence specific binding. The compositions and methods can be used for inhibition of micro RNAs and other relatively short non-coding RNAs.

公开(公告)号：US09783804B2

公开(公告)日：2017-10-10

申请号：US15217007

申请日：2016-07-22

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Christopher Burnett ,  Nitin Puri ,  Susan Magdaleno ,  Alexander Vlassov

IPC: A61K31/70 ,  C07H21/02 ,  C07H21/04 ,  C12N15/113 ,  C12N15/11 ,  A61K31/713 ,  A61K47/48 ,  C12N5/00

CPC classification number: C12N15/113 ,  A61K31/713 ,  A61K47/50 ,  C12N15/111 ,  C12N2310/113 ,  C12N2310/141 ,  C12N2310/321 ,  C12N2310/322 ,  C12N2310/3231 ,  C12N2310/332 ,  C12N2310/3515 ,  C12N2310/3519 ,  C12N2310/51 ,  C12N2310/531 ,  C12N2330/31

Abstract: The invention relates generally to compositions and methods for inhibiting the function of target nucleic acids by sequence specific binding. The compositions and methods can be used for inhibition of micro RNAs and other relatively short non-coding RNAs.

公开(公告)号：US09410153B2

公开(公告)日：2016-08-09

申请号：US14564573

申请日：2014-12-09

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Christopher Burnett ,  Nitin Puri ,  Susan Magdaleno ,  Alexander Vlassov

IPC: A61K31/70 ,  C07H21/02 ,  C07H21/04 ,  C12N15/113 ,  C12N15/11 ,  C12N5/00

CPC classification number: C12N15/113 ,  A61K31/713 ,  A61K47/50 ,  C12N15/111 ,  C12N2310/113 ,  C12N2310/141 ,  C12N2310/321 ,  C12N2310/322 ,  C12N2310/3231 ,  C12N2310/332 ,  C12N2310/3515 ,  C12N2310/3519 ,  C12N2310/51 ,  C12N2310/531 ,  C12N2330/31

Abstract: The invention relates generally to compositions and methods for inhibiting the function of target nucleic acids by sequence specific binding. The compositions and methods can be used for inhibition of micro RNAs and other relatively short non-coding RNAs.