公开(公告)号：US10577647B2

公开(公告)日：2020-03-03

申请号：US14270785

申请日：2014-05-06

Applicant: LUMINEX CORPORATION

Inventor： Douglas F. Whitman ,  Hongwei Zhang

IPC: C12Q1/68 ,  C12Q1/6818 ,  C12Q1/6876 ,  C12Q1/6853 ,  C12Q1/6816 ,  C12Q1/6823 ,  C12Q1/6834

Abstract: Methods and compositions for nucleic acid amplification, detection, and genotyping techniques are disclosed. In one embodiment, a nucleic acid molecule having a target-specific primer sequence; an anti-tag sequence 5′ of the target-specific primer sequence; a tag sequence 5′ of the anti-tag sequence; and a blocker between the anti-tag sequence and the tag sequence is disclosed. Compositions containing such a nucleic acid molecule and methods of using such a nucleic acid molecule are also disclosed.

公开(公告)号：US20140242586A1

公开(公告)日：2014-08-28

申请号：US14270785

申请日：2014-05-06

Applicant: LUMINEX CORPORATION

Inventor： Douglas F. WHITMAN ,  Hongwei Zhang

IPC: C12Q1/68

Abstract: Methods and compositions for nucleic acid amplification, detection, and genotyping techniques are disclosed. In one embodiment, a nucleic acid molecule having a target-specific primer sequence; an anti-tag sequence 5′ of the target-specific primer sequence; a tag sequence 5′ of the anti-tag sequence; and a blocker between the anti-tag sequence and the tag sequence is disclosed. Compositions containing such a nucleic acid molecule and methods of using such a nucleic acid molecule are also disclosed.

Abstract translation: 公开了用于核酸扩增，检测和基因分型技术的方法和组合物。 在一个实施方案中，具有靶特异性引物序列的核酸分子; 靶标特异性引物序列的抗标签序列5'; 抗标签序列的标签序列5'; 并且公开了抗标签序列和标签序列之间的阻断剂。 还公开了含有这种核酸分子的组合物和使用这种核酸分子的方法。

公开(公告)号：US11319577B2

公开(公告)日：2022-05-03

申请号：US16750319

申请日：2020-01-23

Applicant: LUMINEX CORPORATION

Inventor： Douglas F. Whitman ,  Hongwei Zhang

IPC: C12Q1/68 ,  C12Q1/6818 ,  C12Q1/6876 ,  C12Q1/6853 ,  C12Q1/6816 ,  C12Q1/6823 ,  C12Q1/6834 ,  C12Q1/6813

Abstract: Methods and compositions for nucleic acid amplification, detection, and genotyping techniques are disclosed. In one embodiment, a nucleic acid molecule having a target-specific primer sequence; an anti-tag sequence 5′ of the target-specific primer sequence; a tag sequence 5′ of the anti-tag sequence; and a blocker between the anti-tag sequence and the tag sequence is disclosed. Compositions containing such a nucleic acid molecule and methods of using such a nucleic acid molecule are also disclosed.

公开(公告)号：US11884965B2

公开(公告)日：2024-01-30

申请号：US17709693

申请日：2022-03-31

Applicant: LUMINEX CORPORATION

Inventor： Douglas F. Whitman ,  Hongwei Zhang

IPC: C12P19/34 ,  C12Q1/6818 ,  C12Q1/6876 ,  C12Q1/6853 ,  C12Q1/6816 ,  C12Q1/6823 ,  C12Q1/6834 ,  C12Q1/68 ,  C12Q1/6813

CPC classification number: C12Q1/6818 ,  C12Q1/68 ,  C12Q1/6813 ,  C12Q1/6816 ,  C12Q1/6823 ,  C12Q1/6834 ,  C12Q1/6853 ,  C12Q1/6876 ,  C12Q1/6823 ,  C12Q2525/186 ,  C12Q2525/301 ,  C12Q2561/109 ,  C12Q1/6816 ,  C12Q2525/186 ,  C12Q2525/301 ,  C12Q2561/109 ,  C12Q1/6834 ,  C12Q2525/186 ,  C12Q2525/301 ,  C12Q2561/109 ,  C12Q2563/149

Abstract: Methods and compositions for nucleic acid amplification, detection, and genotyping techniques are disclosed. In one embodiment, a nucleic acid molecule having a target-specific primer sequence; an anti-tag sequence 5′ of the target-specific primer sequence; a tag sequence 5′ of the anti-tag sequence; and a blocker between the anti-tag sequence and the tag sequence is disclosed. Compositions containing such a nucleic acid molecule and methods of using such a nucleic acid molecule are also disclosed.