公开(公告)号：US20200330544A1

公开(公告)日：2020-10-22

申请号：US16756757

申请日：2018-10-16

申请人： LAILA NUTRACEUTICALS ,  P.L. THOMAS-LAILA NUTRACEUTICALS, INC.

发明人： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Venkateswara Rao CHIRRAVURI ,  Venkateswarlu SOMEPALLI ,  Kiran BHUPATHIRAJU

IPC分类号： A61K36/9066 ,  A61K36/75 ,  A23L33/105

摘要： Synergistic herbal compositions comprising combination of extracts, fractions or phytochemicals or mixtures thereof derived from Moringa oleifera, Murraya koenigii and Curcuma longa for increasing lean body mass and brown adipose tissue; for accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (BAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products. The invention further provides a method of increasing lean body mass and brown adipose tissue; accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (BAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products in mammals.

公开(公告)号：US20210338757A1

公开(公告)日：2021-11-04

申请号：US16479798

申请日：2017-01-19

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIRAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Krishanu SENGUPTHA ,  Venkata Krishna Raju ALLURI

IPC分类号： A61K36/22 ,  A61K36/38 ,  A61K45/06 ,  A23L33/105 ,  A61K9/00 ,  A61P15/10

摘要： The invention discloses synergistic compositions comprising extracts, fractions or pure compounds derived from at least two herbs selected from Punica granatum, Mangifera indica and Garcinia mangostana for inhibiting the expression/production/activity of Phosphodiesterase 5 (PDE5) enzyme or for increasing cGMP levels in a male subject. The invention further discloses a method of inhibiting the expression/production/activity of Phosphodiesterase 5 (PDE5) enzyme, increasing cGMP levels and sexual arousal, treating/alleviating various aspects of male sexual dysfunction or impotence such as erectile dysfunction, loss of libido, or orgasm/ejaculation disorders in a male subject by using a suitable dose of synergistic composition comprising extracts, fractions or pure compounds derived from at least two herbs selected from Punica granatum, Mangifera indica and Garcinia mangostana.

公开(公告)号：US20210138014A1

公开(公告)日：2021-05-13

申请号：US16492473

申请日：2018-03-08

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIRAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Krishanu SENGUPTHA ,  Venkata Krishna Raju ALLURI ,  Venkateswarlu SOMEPALLI

IPC分类号： A61K36/54 ,  A61K36/22 ,  A61K36/31 ,  A61K36/71 ,  A61K36/8962

摘要： Synergistic herbal compositions for Testosterone boosting comprising at least two ingredients selected from the extracts, fractions or pure phytochemicals derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The present invention also describes a synergistic composition comprising at least one testosterone booster ingredient selected from the extracts, fractions or pure phytochemical derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica and at least one aromatase inhibitor ingredient selected from the extracts, fractions or pure phytochemicals derived from Allium cepa, Tamarindus indica and Cinnamomum tamala for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The invention further provides methods of improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans.

公开(公告)号：US20140056987A1

公开(公告)日：2014-02-27

申请号：US14065583

申请日：2013-10-29

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju GOKARAJU ,  Rama Raju Gokaraju ,  Venkata Kanaka Ranga Raju Gokaraju ,  Trimurtulu Golakoti ,  Kiran Bhupthiraju ,  Venkata Krishna Raju Alluri ,  Krishanu Sengupta

IPC分类号： A61K36/185 ,  A61K36/9066 ,  A61K36/19 ,  A61K31/202 ,  A61K31/355 ,  A61K31/198 ,  A61K36/324 ,  A61K31/375

CPC分类号： A61K36/185 ,  A61K31/07 ,  A61K31/198 ,  A61K31/202 ,  A61K31/355 ,  A61K31/365 ,  A61K31/375 ,  A61K31/592 ,  A61K31/714 ,  A61K33/04 ,  A61K33/06 ,  A61K35/612 ,  A61K36/19 ,  A61K36/324 ,  A61K36/9066 ,  A61K2300/00

摘要： The invention discloses synergistic composition comprising at least one Annona squamosa derived component standardized to acetogenin compound(s) having α,β-unsaturated-γ-methyl-γ-lactone moiety in combination with at least one biologically active ingredient derived from plants, animals or microorganisms such as vitamins, amino acids, minerals, fibers, various plant and herbal extracts for the prevention, treatment, inhibition or controlling inflammation and/or metabolic disorders and other associated or related diseases. The invention further discloses the method of treating inflammation and/or metabolic disorders and other associated or related diseases.

摘要翻译： 本发明公开了包含至少一种标准化为具有α，β-不饱和-γ-甲基-γ-内酯部分的乙酰辅酶化合物与至少一种源自植物，动物或生物活性成分的生物活性成分的Annona squamosa衍生组分的协同组合物 微生物如维生素，氨基酸，矿物质，纤维，各种植物和草药提取物，用于预防，治疗，抑制或控制炎症和/或代谢紊乱以及其它相关或相关疾病。 本发明还公开了治疗炎症和/或代谢紊乱及其它相关或相关疾病的方法。

公开(公告)号：US20230241152A1

公开(公告)日：2023-08-03

申请号：US18000146

申请日：2021-05-29

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju GOKARAJU ,  Rama Raju Gokaraju ,  Kiran BHUPATHIRAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Krishanu SENGUPTHA ,  Venkateswarlu SOMEPALLI ,  Venkata Krishna Raju ALLURI

IPC分类号： A61K36/888 ,  A23L33/00 ,  A23L33/105 ,  A61K36/185 ,  A61K36/81 ,  A61P1/14

CPC分类号： A61K36/888 ,  A23L33/40 ,  A23L33/105 ,  A61K36/185 ,  A61K36/81 ,  A61P1/14 ,  A61K2236/331 ,  A61K2236/333

摘要： Synergistic Herbal Compositions For Improving Gut Health” The present invention discloses synergistic herbal compositions comprising at least two ingredients selected from extract(s), fraction(s), phytochemical(s), or mixtures thereof derived each one from a different herb selected from Abelmoschus esculentus, Withania somnifera and Amorphophallus paeoniifolius; improving at least one gut health function selected from gut-brain axis, easing of constipation, bowel movement, improved GI motility, digestion and gut immunity; and reducing gut inflammation. The invention further relates to methods of treatment and the use of the compositions.

公开(公告)号：US20180168655A1

公开(公告)日：2018-06-21

申请号：US15897886

申请日：2018-02-15

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Venketa Kanaka Ranga Raju GOKARAJU ,  Kiran BHUPATHIRAJU ,  Trimurtulu GOLAKATI ,  Krishanu SENGUPTA ,  Venkata Krishna Raju ALLURI

IPC分类号： A61B17/11 ,  A61F2/06

CPC分类号： A61B17/11 ,  A23L33/105 ,  A23V2002/00 ,  A61B2017/1107 ,  A61B2017/1132 ,  A61B2017/1135 ,  A61F2/064 ,  A61K36/28 ,  A61K36/38 ,  A61K36/53 ,  A61K36/54 ,  A61K36/9066 ,  A61K2300/00 ,  A23V2200/316 ,  A23V2200/322

摘要： The present invention discloses novel synergistic dietary supplement compositions comprising at least two ingredients selected from the extracts and fractions derived from Sphaeranthus indicus, Coleus aromaticus, Cissus quadrangularis, Curcuma longa, Garcinia mangostana, Citrullus lanatus, Ocimum sanctum, Trachyspermum ammi and Cinnamomum tamala as natural energy enhancer for enhancing physical performance, muscle strength, muscle mass, mental alertness and energy levels in a mammal.

公开(公告)号：US20130136809A1

公开(公告)日：2013-05-30

申请号：US13752181

申请日：2013-01-28

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIRAJU ,  Krishanu SENGUPTA

IPC分类号： A61K31/5377 ,  A61K31/437 ,  A61K31/19 ,  A61K31/365 ,  A61K45/06

CPC分类号： A61K31/365 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/19 ,  A61K31/352 ,  A61K31/437 ,  A61K31/5377 ,  A61K35/12 ,  A61K36/28 ,  A61K36/38 ,  A61K45/06 ,  A61K2300/00 ,  A23V2250/21

摘要： The invention discloses biologically active ingredient(s) selected from 7-hydroxyfrullanolide, its analogs, the ex-tract(s) and fraction(s) standardized to 7-hydroxyfrullanolide or its analogs or both or mixtures thereof or their composition(s) for the prevention, control and treatment of one or more obesity, overweight, metabolic syndrome, diabetes and other metabolic disorders or for producing lean body mass in a warm blooded animal in need thereof.

摘要翻译： 本发明公开了生物活性成分，其选自7-羟基富勒烯内酯，其类似物，标准化为7-羟基果糖内酯的前体和级分或其类似物或两者或其混合物或其组合物， 预防，控制和治疗一种或多种肥胖，超重，代谢综合征，糖尿病和其他代谢紊乱，或用于在有需要的温血动物中产生瘦体重。

公开(公告)号：US20230346736A1

公开(公告)日：2023-11-02

申请号：US18012411

申请日：2021-06-23

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Kiran BHUPATHIRAJU ,  Venkata Krishna Raju ALLURI ,  Venkateswarlu SOMEPALLI ,  Krishanu SENGUPTHA

IPC分类号： A61K31/22 ,  A61P21/00 ,  A61K33/00

CPC分类号： A61K31/22 ,  A61K33/00 ,  A61P21/00

摘要： The present invention discloses water-soluble 3-O-acetyl-11-keto-β-boswellic acid compositions comprising 3-O-acetyl-11-keto-β-boswellic acid in combination with a metal ion selected from potassium or sodium in the form of respective metal salt or complex or chelate; process for their preparation; methods of prevention, control and/or treatment of at least one disorder selected from muscle soreness, delayed-onset of muscle soreness (DOMS), muscles tenderness, muscle pain, muscle fatigue, muscle sprain, temporary loss of muscle strength and swelling in muscles.

公开(公告)号：US20210236572A1

公开(公告)日：2021-08-05

申请号：US17054079

申请日：2019-05-08

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Kiran BHUPATHIRAJU ,  Trimurtulu GOLAKOTI ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Venkateswarlu SOMEPALLI ,  Venkata Krishna Raju ALLURI

IPC分类号： A61K36/185 ,  A23L33/105 ,  A61P5/24 ,  A61K31/522 ,  A23L33/24 ,  A61K47/38 ,  A61K45/06 ,  A61K31/7048

摘要： Synergistic herbal compositions comprising combination of a first ingredient selected from the extract(s), fraction(s), active compound(s) and phytochemicals or mixtures thereof derived from the plant parts of Punica granatum and a second ingredient selected from the extract(s), fraction(s), active compound(s) and phytochemicals or mixtures thereof derived from the plant parts of Theobroma cacao for improving testosterone levels. The invention further provides the method of obtaining at least one health benefit tin related to enhanced anabolic and androgenic activities in the body selected from improving testosterone levels, energy levels, sustained energy, vigor, stamina, healthy aging, cellular longevity, muscle mass, muscle strength sexual function (libido and erectile function) and psychological well-being (mood and focus); and reducing stress in humans and alleviating the symptoms associated with the low levels of testosterone in humans such as loss of libido, loss of erectile function, abdominal obesity, decreased muscle mass and strength, fatigue, mood swing, decreased bone density, decreased motivation, and decreased memory and concentration.

公开(公告)号：US20210046135A1

公开(公告)日：2021-02-18

申请号：US16978905

申请日：2019-03-05

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju GOKARAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIRAJU ,  Venkateswarlu SOMEPALLI ,  Venkata Krishna Raju ALLURI ,  Krishanu SENGUPTHA

IPC分类号： A61K36/185 ,  A61K36/752 ,  A61K47/36 ,  A61P3/04 ,  A61K9/00 ,  A61K9/68 ,  A23L33/105 ,  A23L33/00 ,  A23L33/125 ,  A23L29/30

摘要： The invention discloses synergistic herbal composition comprising combination of first ingredient selected from extracts, fractions, phytochemicals and mixtures thereof derived from Theobroma cacao and a second ingredient selected from extracts, fractions, phytochemical and mixtures thereof derived from Citrus aurantifolia for obtaining at least one health benefit selected from preventing, controlling or treating obesity and/or overweight; improving lean body mass, improving the browning of White Adipose Tissue/improving formation of brown adipose tissue, increasing basal metabolic rate/resting energy expenditure, increasing thermogenesis, improving thyroid function, maintaining healthy body weight, increasing satiety/, supporting weight loss, improving fat loss and maintaining a slim body. The invention further discloses synergistic herbal compositions comprising Theobroma cacao and Citrus aurantifolia and optionally comprises at least one ingredient selected from pharmaceutically acceptable excipient/diluent/carrier; methods of treatment and use for the prevention and treatment of obesity/overweight or improving lean body mass or resting energy expenditure in a human or animal.