公开(公告)号：US11801277B2

公开(公告)日：2023-10-31

申请号：US16978905

申请日：2019-03-05

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju Gokaraju ,  Venkata Kanaka Ranga Raju Gokaraju ,  Rama Raju Gokaraju ,  Trimurtulu Golakoti ,  Kiran Bhupathiraju ,  Venkateswarlu Somepalli ,  Venkata Krishna Raju Alluri ,  Krishanu Senguptha

IPC分类号： A61K36/185 ,  A23L29/30 ,  A23L33/105 ,  A23L33/125 ,  A23L33/00 ,  A61P3/04 ,  A61K9/00 ,  A61K9/68 ,  A61K36/752 ,  A61K47/36

CPC分类号： A61K36/185 ,  A23L29/35 ,  A23L33/105 ,  A23L33/125 ,  A23L33/40 ,  A61K9/0056 ,  A61K9/0058 ,  A61K36/752 ,  A61K47/36 ,  A61P3/04 ,  A23V2002/00 ,  A61K2236/333

摘要： The invention discloses synergistic herbal composition comprising combination of first ingredient selected from extracts, fractions, phytochemicals and mixtures thereof derived from Theobroma cacao and a second ingredient selected from extracts, fractions, phytochemical and mixtures thereof derived from Citrus aurantifolia for obtaining at least one health benefit selected from preventing, controlling or treating obesity and/or overweight; improving lean body mass, improving the browning of White Adipose Tissue/improving formation of brown adipose tissue, increasing basal metabolic rate/resting energy expenditure, increasing thermogenesis, improving thyroid function, maintaining healthy body weight, increasing satiety/, supporting weight loss, improving fat loss and maintaining a slim body. The invention further discloses synergistic herbal compositions comprising Theobroma cacao and Citrus aurantifolia and optionally comprises at least one ingredient selected from pharmaceutically acceptable excipient/diluent/carrier; methods of treatment and use for the prevention and treatment of obesity/overweight or improving lean body mass or resting energy expenditure in a human or animal.

公开(公告)号：US11576941B2

公开(公告)日：2023-02-14

申请号：US16312150

申请日：2017-06-21

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju Gokaraju ,  Rama Raju Gokaraju ,  Kishore Babu Govada ,  Venkata Krishna Raju Alluri ,  Nagendra Babu Vutti ,  Kiran Bhupathiraju ,  Venkata Kanaka Ranga Raju Gokaraju ,  Trimurtulu Golakoti

IPC分类号： A61K36/68 ,  A23L33/105 ,  A23L27/00 ,  A61K9/16 ,  A61K31/7048 ,  A61K47/32 ,  A61K47/36 ,  A61K47/44 ,  A61K36/19 ,  A61K36/22 ,  A61K36/324 ,  A61K36/38 ,  A61K36/42 ,  A61K36/58 ,  A61K36/81

摘要： The invention discloses taste masking formulations for bitter natural compounds, selected from the extracts, fraction and pure phytochemicals produced in combination with a synthetic polymer or a natural polymer. The invention also relates to the novel process of producing the taste masking formulations. The invention also relates to taste masking formulations of Bacopa extracts with no bitter taste or negligible bitter taste in combination with synthetic polymers such as Eudragit or natural polymers such as Shellac.

公开(公告)号：US10206964B2

公开(公告)日：2019-02-19

申请号：US14735360

申请日：2015-06-10

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju Gokaraju ,  Rama Raju Gokaraju ,  Venkata Kanaka Ranga Raju Gokaraju ,  Trimurtulu Golakoti ,  Kiran Bhupathiraju ,  Venkata Krishna Raju Alluri

IPC分类号： A61K36/324

摘要： The present invention discloses synergistic nutraceutical or pharmaceutical or dietary supplement anti-inflammatory compositions comprising therapeutically effective combination of an extract selectively enriched in 3-O-acetyl-1 1-keto-β-boswellic acid (AKBA) derived from Boswellia serrata and Boswellia serrata non-acidic resin extract (BNRE). The composition(s) can be used to prevent, control and treat inflammation and several inflammatory related diseases including asthma, osteoarthritis, rheumatoid arthritis, endothelial dysfunction and the like. The invention further discloses the amelioration of pro-inflammatory biomarker proteins or molecules, whose expression/production is altered during inflammatory diseases.

公开(公告)号：US09795646B2

公开(公告)日：2017-10-24

申请号：US14451565

申请日：2014-08-05

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju Gokaraju ,  Rama Raju Gokaraju ,  Venkata Kanaka Ranga Raju Gokaraju ,  Trimurtulu Golakoti ,  Kiran Bhupathiraju ,  Venkata Krishna Raju Alluri

IPC分类号： A61K36/38 ,  A61K36/68 ,  A61K36/28 ,  A61K45/06 ,  A61K36/324 ,  A61K31/12 ,  A61K31/56 ,  A61K36/9066 ,  A61K35/60

CPC分类号： A61K36/324 ,  A61K31/12 ,  A61K31/56 ,  A61K35/60 ,  A61K36/28 ,  A61K36/38 ,  A61K36/68 ,  A61K36/9066 ,  A61K45/06 ,  A61K2300/00

摘要： The present disclosure relates to non-acidic extracts or fractions selected from a Boswellia low polar gum resin extract fraction (BLPRE), a Boswellia volatile oil fraction (BVOIL), and a Boswellia oil fraction (BOIL) and their compositions. BLPRE, BOIL, and BVOIL are each derived from the gum resin of a Boswellia species. These compositions are useful for improving mental condition, enhancing brain functions such as cognition, memory, learning, communication and brain health, for treating impaired memory, and for preventing, control or treating memory and cognition related disorders/diseases. Additionally, BOIL, BVOIL, and mixtures of BOIL and BVOIL are useful for enhancing the bioavailability of a biological agent.

公开(公告)号：US11903991B2

公开(公告)日：2024-02-20

申请号：US17201865

申请日：2021-03-15

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju Gokaraju ,  Rama Raju Gokaraju ,  Venkata Kanaka Ranga Raju Gokaraju ,  Trimurtulu Golakati ,  Kiran Bhupathiraju ,  Venkata Krishna Raju Alluri ,  Krishanu Sengupta

IPC分类号： A61K36/00 ,  A61K36/9066 ,  A61K36/185 ,  A61K36/324 ,  A61K45/06

CPC分类号： A61K36/9066 ,  A61K36/185 ,  A61K36/324 ,  A61K45/06 ,  A61K2236/15 ,  A61K2236/31 ,  A61K2236/33 ,  A61K2236/331 ,  A61K2236/35 ,  A61K2236/39 ,  A61K2236/51 ,  A61K2236/55 ,  A61K36/185 ,  A61K2300/00 ,  A61K36/324 ,  A61K2300/00 ,  A61K36/9066 ,  A61K2300/00

摘要： A method for treating an inflammation, arthritis, or a joint disease in a patient in need thereof, comprising administering to the patient an herbal composition, where the herbal composition includes a therapeutically effective amount of an extract of Terminalia chebula; a therapeutically effective amount of an extract of Curcuma longa; and a therapeutically effective amount of a non-acidic, water-immiscible organic solvent extract of a Boswellia serrata resin.

公开(公告)号：US20230293620A1

公开(公告)日：2023-09-21

申请号：US18041467

申请日：2021-08-16

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju Gokaraju ,  Rama Raju Gokaraju ,  Kiran Bhupathiraju ,  Venkata Kanaka Ranga Raju Gokaraju ,  Trimurtulu Golakoti ,  Venkateswarlu Somepalli ,  Venkata Krishna Raju Alluri ,  Krishanu Senguptha

IPC分类号： A61K36/81 ,  A61K36/59 ,  A61K36/19 ,  A61K33/06 ,  A61K33/30 ,  A61P37/02 ,  A61P29/00

CPC分类号： A61K36/81 ,  A61K36/59 ,  A61K36/19 ,  A61K33/06 ,  A61K33/30 ,  A61P37/02 ,  A61P29/00

摘要： The present invention discloses synergistic herbal compositions comprising a first ingredient Terminalia chebula extract containing metal salt or metal complex or metal chelate of at least one phytochemical in the extract selected from chebulagic acid, chebulinic acid, and gallic acid or mixtures thereof; and a second ingredient selected from extract(s), fraction(s), phytochemical(s) or mixtures thereof derived from Withania somnifera, Tinospora cordifolia and Andrographis paniculata; process for their preparation, methods of treatment and use of such compositions for improving immunity and respiratory health.

公开(公告)号：US11684648B2

公开(公告)日：2023-06-27

申请号：US16492473

申请日：2018-03-08

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju Gokaraju ,  Rama Raju Gokaraju ,  Trimurtulu Golakoti ,  Kiran Bhupathiraju ,  Venkata Kanaka Ranga Raju Gokaraju ,  Krishanu Senguptha ,  Venkata Krishna Raju Alluri ,  Venkateswarlu Somepalli

IPC分类号： A61K36/54 ,  A61K36/22 ,  A61K36/31 ,  A61K36/71 ,  A61K36/8962 ,  A61P5/24 ,  A61K36/48

CPC分类号： A61K36/54 ,  A61K36/22 ,  A61K36/31 ,  A61K36/71 ,  A61K36/8962 ,  A61P5/24 ,  A61K36/48 ,  A61K2300/00

摘要： Synergistic herbal compositions for Testosterone boosting comprising at least two ingredients selected from the extracts, fractions or pure phytochemicals derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The present invention also describes a synergistic composition comprising at least one testosterone booster ingredient selected from the extracts, fractions or pure phytochemical derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica and at least one aromatase inhibitor ingredient selected from the extracts, fractions or pure phytochemicals derived from Allium cepa, Tamarindus indica and Cinnamomum tamala for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The invention further provides methods of improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans.

公开(公告)号：US10953067B2

公开(公告)日：2021-03-23

申请号：US15229710

申请日：2016-08-05

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju Gokaraju ,  Rama Raju Gokaraju ,  Venkata Kanaka Ranga Raju Gokaraju ,  Trimurtulu Golakati ,  Kiran Bhupathiraju ,  Venkata Krishna Raju Alluri ,  Krishanu Sengupta

IPC分类号： A61K36/9066 ,  A61K36/185 ,  A61K36/324 ,  A61K45/06

摘要： An herbal composition, comprising a therapeutically effective amount of an extract of Terminalia chebula; a therapeutically effective amount of an extract of Curcuma longa; and a therapeutically effective amount of a non-acidic, water-immiscible organic solvent extract of a Boswellia serrata resin.

公开(公告)号：US10471114B2

公开(公告)日：2019-11-12

申请号：US14951175

申请日：2015-11-24

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju Gokaraju ,  Rama Raju Gokaraju ,  Venkata Kanaka Ranga Raju Gokaraju ,  Trimurtulu Golakoti ,  Kiran Bhupathiraju ,  Krishanu Sengupta ,  Venkata Krishna Raju Alluri

IPC分类号： A61K36/38 ,  A61K36/28 ,  A61K35/12 ,  A23L33/105

摘要： Pharmaceutical/dietary supplements and food ingredient(s) derived from Sphaeranthus indicus are used for controlling or treating a metabolic disorder. The supplements and food ingredient(s) are selected from Sphaeranthus indicus extract(s), fraction(s), active compound(s) and phytochemical(s) or mixtures thereof and their compositions, preferably in combination with at least one component selected from the extract(s), fraction(s), active compound(s) and phytochemical(s) or mixtures thereof derived from Garcinia mangostana. The ingredients and the composition(s) can be used for the control, prevention and treatment of obesity, metabolic syndrome, diabetes and other metabolic disorders, and also to regulate energy expenditure, prevention of atherosclerotic plaques in coronary artery and abdominal aorta, increase insulin sensitivity, improve glucose tolerance, lower triglyceride levels and balance glucose levels in mammals.

公开(公告)号：US20140056987A1

公开(公告)日：2014-02-27

申请号：US14065583

申请日：2013-10-29

申请人： LAILA NUTRACEUTICALS

发明人： Ganga Raju GOKARAJU ,  Rama Raju Gokaraju ,  Venkata Kanaka Ranga Raju Gokaraju ,  Trimurtulu Golakoti ,  Kiran Bhupthiraju ,  Venkata Krishna Raju Alluri ,  Krishanu Sengupta

IPC分类号： A61K36/185 ,  A61K36/9066 ,  A61K36/19 ,  A61K31/202 ,  A61K31/355 ,  A61K31/198 ,  A61K36/324 ,  A61K31/375

CPC分类号： A61K36/185 ,  A61K31/07 ,  A61K31/198 ,  A61K31/202 ,  A61K31/355 ,  A61K31/365 ,  A61K31/375 ,  A61K31/592 ,  A61K31/714 ,  A61K33/04 ,  A61K33/06 ,  A61K35/612 ,  A61K36/19 ,  A61K36/324 ,  A61K36/9066 ,  A61K2300/00

摘要： The invention discloses synergistic composition comprising at least one Annona squamosa derived component standardized to acetogenin compound(s) having α,β-unsaturated-γ-methyl-γ-lactone moiety in combination with at least one biologically active ingredient derived from plants, animals or microorganisms such as vitamins, amino acids, minerals, fibers, various plant and herbal extracts for the prevention, treatment, inhibition or controlling inflammation and/or metabolic disorders and other associated or related diseases. The invention further discloses the method of treating inflammation and/or metabolic disorders and other associated or related diseases.

摘要翻译： 本发明公开了包含至少一种标准化为具有α，β-不饱和-γ-甲基-γ-内酯部分的乙酰辅酶化合物与至少一种源自植物，动物或生物活性成分的生物活性成分的Annona squamosa衍生组分的协同组合物 微生物如维生素，氨基酸，矿物质，纤维，各种植物和草药提取物，用于预防，治疗，抑制或控制炎症和/或代谢紊乱以及其它相关或相关疾病。 本发明还公开了治疗炎症和/或代谢紊乱及其它相关或相关疾病的方法。