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公开(公告)号：US08734474B2
公开(公告)日：2014-05-27
申请号：US12648642
申请日：2009-12-29
IPC分类号： A61B17/08
CPC分类号： A61M1/0088 , A61B17/11 , A61B17/1128 , A61F13/00063 , A61F13/00068
摘要： Provided is an apparatus that includes a nerve conduit and a nested manifold for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit and nested manifold, and a conduit for providing fluid communication between the manifold and the source of reduced pressure. Additionally provided is a method that includes implanting the above nerve conduit and manifold at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.
摘要翻译： 提供了一种装置，其包括用于提供减压的神经管道和嵌套歧管。 还提供了包括减压源，神经管道和嵌套歧管的系统，以及用于在歧管和减压源之间提供流体连通的导管。 另外提供了一种方法，其包括将上述神经导管和歧管植入损伤的神经组织的部位，并将减压施加到歧管，从而刺激神经组织的修复或再生长。
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公开(公告)号：US08449562B2
公开(公告)日：2013-05-28
申请号：US13554724
申请日：2012-07-20
IPC分类号： A61B17/08
CPC分类号： A61M1/0088 , A61B17/11 , A61B17/1128 , A61F13/00063 , A61F13/00068
摘要： Provided is an apparatus that includes a nerve conduit, a manifold and a support structure for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit, a manifold, a support structure and a conduit for providing fluid communication between the manifold support and the source of reduced pressure. Additionally provided is a method that includes implanting the above nerve conduit, manifold and support structure at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.
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公开(公告)号：US09125766B2
公开(公告)日：2015-09-08
申请号：US12648475
申请日：2009-12-29
CPC分类号： A61M1/0088 , A61B17/11 , A61B17/1128 , A61F13/00063 , A61F13/00068
摘要： An apparatus and system for treating a wound having a cavity is disclosed. The apparatus comprises a scaffold including a scaffold lamina and a tissue lamina wherein the scaffold lamina forms a laminate in fluid communication with the tissue lamina. The laminate is rolled into a generally cylindrical shape having two end surfaces. The apparatus further comprises a manifold having a port for coupling to a source of reduced pressure and that is positioned in fluid communication with the scaffold to provide reduced pressure to the scaffold lamina and the wound. The apparatus also comprises a drape formed of substantially impermeable material to cover the scaffold and the manifold within the wound. A method for treating a wound having a cavity is also disclosed and comprises positioning a scaffold lamina adjacent a tissue lamina to form a laminate in fluid communication with the tissue lamina, rolling the laminate into a generally cylindrical shape having two end surface, and positioning the scaffold within the cavity of the wound to provide reduced pressure to the wound. The method further comprises positioning a manifold in fluid communication with the scaffold to provide reduced pressure to the scaffold lamina and the wound.
摘要翻译： 公开了一种用于处理具有空腔的伤口的装置和系统。 该装置包括支架，其包括支架层和组织层，其中支架层形成与组织层流体连通的层压体。 将层压体卷成具有两个端面的大致圆柱形的形状。 该装置还包括具有用于联接到减压源的端口并且与支架流体连通的歧管，以向支架层和伤口提供减压。 该装置还包括由基本上不可渗透的材料形成的覆盖物，以覆盖伤口内的支架和歧管。 还公开了一种用于治疗具有空腔的伤口的方法，并且包括将支架层定位在组织层附近以形成与组织层流体连通的层压体，将层压体滚动成具有两个端面的大致圆柱形形状， 在伤口的空腔内的支架，以向伤口提供减压。 该方法还包括将歧管定位成与支架流体连通以向支架层和伤口提供减压。
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公开(公告)号：US08734409B2
公开(公告)日：2014-05-27
申请号：US12648448
申请日：2009-12-29
CPC分类号： A61F13/00068 , A61B17/88 , A61F2/2846 , A61F13/00063 , A61F2002/2835 , A61F2002/30784 , A61F2002/368 , A61F2013/00357 , A61F2013/00927 , A61K38/18 , A61K38/19 , A61K38/22 , A61K49/223 , A61M1/0023 , A61M1/0088 , A61M27/00 , A61M37/00 , A61M37/0092 , A61N5/062
摘要： Provided is an apparatus that includes a scaffold with a gel or liquid composition deposed on at least a portion of a luminal surface, the gel or liquid composition adapted to include microbubbles. Also provided is a system that includes a source of reduced pressure, the above scaffold, a manifold adjacent the scaffold, and a conduit for providing fluid communication between the manifold and the source of reduced pressure. Additionally provided is a method that includes implanting the above scaffold at the tissue site and disrupting a substantial portion of the microbubbles to induce fluid flow to the scaffold. Further provided is an apparatus that includes a scaffold that comprises a slowly degradable material and a quickly degradable material. Additionally provided is a system for coupling nerve tissue and a microchip assembly.
摘要翻译： 提供了一种装置，其包括具有凝胶或液体组合物的支架，所述支架沉积在腔表面的至少一部分上，所述凝胶或液体组合物适于包含微泡。 还提供了一种包括减压源的系统，上述支架，邻近支架的歧管和用于在歧管和减压源之间提供流体连通的导管。 另外提供了一种方法，其包括将上述支架植入组织部位并破坏大部分微泡以诱导流体流入支架。 还提供了一种装置，其包括包含缓慢降解材料和快速可降解材料的支架。 另外提供了一种用于联接神经组织和微芯片组件的系统。
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公开(公告)号：US08257372B2
公开(公告)日：2012-09-04
申请号：US12648458
申请日：2009-12-29
IPC分类号： A61B17/08
CPC分类号： A61M1/0088 , A61B17/11 , A61B17/1128 , A61F13/00063 , A61F13/00068
摘要： Provided is an apparatus that includes a nerve conduit, a manifold and a support structure for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit, a manifold, a support structure and a conduit for providing fluid communication between the manifold support and the source of reduced pressure. Additionally provided is a method that includes implanting the above nerve conduit, manifold and support structure at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.
摘要翻译： 提供了一种包括神经管道，歧管和用于提供减压的支撑结构的装置。 还提供了一种包括减压源的系统，神经管道，歧管，支撑结构和用于在歧管支撑件和减压源之间提供流体连通的导管。 另外提供了一种方法，其包括在损伤的神经组织的位置处植入上述神经导管，歧管和支撑结构，并将减压施加到歧管，从而刺激神经组织的修复或再生长。
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