-
公开(公告)号:US08937153B2
公开(公告)日:2015-01-20
申请号:US12452731
申请日:2008-07-17
申请人: Lars Abrahmsén , Andreas Jonsson , Jakob Dogan , Per-Åke Nygren
发明人: Lars Abrahmsén , Andreas Jonsson , Jakob Dogan , Per-Åke Nygren
IPC分类号: C07K14/31 , C07K14/315
CPC分类号: C07K14/00 , A61K38/00 , C07K14/31 , C07K14/315 , C07K14/535 , C07K14/605 , C07K14/61 , C07K14/755 , C07K16/18 , C07K2319/00 , C07K2319/70
摘要: The present invention relates to a class of engineered polypeptides having a binding affinity for albumin. It also relates to new methods and uses that exploit binding by these and other compounds to albumin in different contexts, some of which have significance for the treatment of disease in mammals including humans.
摘要翻译: 本发明涉及一类对白蛋白具有结合亲和性的工程化多肽。 它还涉及利用这些和其它化合物在不同背景下结合白蛋白的新方法和用途,其中一些对于包括人在内的哺乳动物的疾病的治疗具有重要意义。
-
公开(公告)号:US20100273979A1
公开(公告)日:2010-10-28
申请号:US12452731
申请日:2008-07-17
申请人: Lars Abrahmsén , Andreas Jonsson , Jakob Dogan , Per-Åke Nygren
发明人: Lars Abrahmsén , Andreas Jonsson , Jakob Dogan , Per-Åke Nygren
IPC分类号: C07K14/31 , C07K14/00 , C07K14/315
CPC分类号: C07K14/00 , A61K38/00 , C07K14/31 , C07K14/315 , C07K14/535 , C07K14/605 , C07K14/61 , C07K14/755 , C07K16/18 , C07K2319/00 , C07K2319/70
摘要: The present invention relates to a class of engineered polypeptides having a binding affinity for albumin. It also relates to new methods and uses that exploit binding by these and other compounds to albumin in different contexts, some of which have significance for the treatment of disease in mammals including humans.
摘要翻译: 本发明涉及一类对白蛋白具有结合亲和性的工程化多肽。 它还涉及利用这些和其它化合物在不同背景下结合白蛋白的新方法和用途,其中一些对于包括人在内的哺乳动物的疾病的治疗具有重要意义。
-
公开(公告)号:US20130039711A1
公开(公告)日:2013-02-14
申请号:US13641675
申请日:2010-04-16
申请人: Andreas Jonsson , Robert Johansson
发明人: Andreas Jonsson , Robert Johansson
CPC分类号: B23Q5/36 , B25H1/0064 , Y10T408/16 , Y10T408/17 , Y10T408/5647 , Y10T408/675 , Y10T408/6771
摘要: The present invention relates to methods and systems for automatically feeding a feeding housing (206) of a drilling device (200). The drilling device (200) includes a drill stand (202), a drilling machine (204) and a feeding housing (206). Further, the drilling machine (204), which is suspended by the feeding housing (206), includes a drill with a drilling motor for performing a drilling operation through a drilling object. The feeding unit (208) includes an electric feeding motor for feeding the feeding housing (206) along the stand (202). Further, the feeding unit (208) also includes a controller for manually influencing the feeding motor's direction of rotation, speed and feeding force.
摘要翻译: 本发明涉及用于自动馈送钻井装置(200)的进给壳体(206)的方法和系统。 钻孔装置(200)包括钻台(202),钻机(204)和进料壳体(206)。 此外,由进给壳体(206)悬挂的钻孔机(204)包括具有用于通过钻孔对象进行钻孔操作的钻孔马达的钻头。 馈送单元(208)包括用于沿着支架(202)馈送馈送壳体(206)的馈电电动机。 此外,进给单元(208)还包括用于手动影响进给马达的旋转方向,速度和进给力的控制器。
-
公开(公告)号:US09373078B1
公开(公告)日:2016-06-21
申请号:US13453926
申请日:2012-04-23
申请人: Anders Olsson , Roman Jugai , Andreas Jonsson
发明人: Anders Olsson , Roman Jugai , Andreas Jonsson
CPC分类号: G06Q10/107 , G06F17/30294 , G06F17/3051 , G06F17/30536 , G06N5/04 , G06N5/048
摘要: Systems and methods to provide predictive alerting are disclosed. Trends and characteristics in the data may be identified in advance of actual occurrence, with an expected event being predicted or extrapolated based on data and a predictive model associated with stored and/or incoming data. This may be done by, for example, developing a set of rules associated with the model that may then be used to trigger predictive alerts based on predicted trends. Various data and associated characteristics may be determined based on past data and/or analogous data taken from similarly modeled systems. For example, seasonal trends may be factored into the model so that a prediction is based on both a received set of data and expected seasonal (or other temporal) trends. Various other characteristics may also be used in the predictive model.
摘要翻译: 公开了提供预测性警报的系统和方法。 数据中的趋势和特征可以在实际发生之前被识别,其中基于数据和与存储和/或输入数据相关联的预测模型预测或外推预期事件。 这可以通过例如开发与模型相关联的一组规则来完成,所述规则然后可以用于基于预测趋势触发预测警报。 可以基于从类似建模的系统获取的过去数据和/或类似数据来确定各种数据和相关特征。 例如,季节性趋势可以被分解到模型中,使得预测基于所接收的一组数据和预期的季节(或其他时间)趋势。 预测模型中也可以使用各种其他特征。
-
公开(公告)号:US09107965B2
公开(公告)日:2015-08-18
申请号:US14055443
申请日:2013-10-16
IPC分类号: A61K38/00 , A61K38/22 , C07K14/485 , C07K5/00 , C07K7/00 , C07K16/00 , C07K17/00 , A61K51/00 , A61M36/14 , A61K51/08 , A61K38/18 , C07K14/31 , A61K49/14
CPC分类号: A61K51/088 , A61K38/1808 , A61K49/14 , C07K14/31 , C07K14/485 , C07K2319/20 , C07K2319/21 , C07K2319/22
摘要: This invention relates to polypeptides which bind to EGFR family receptors and to applications of those polypeptides in medicine, veterinary medicine, diagnosis, diagnostics, and imaging.
摘要翻译: 本发明涉及结合EGFR家族受体的多肽以及这些多肽在医药,兽医学,诊断,诊断和成像中的应用。
-
公开(公告)号:US20120180773A1
公开(公告)日:2012-07-19
申请号:US13387687
申请日:2010-07-21
CPC分类号: B28D1/084 , B27B17/0083 , B27B17/08 , B27B17/14
摘要: An interchangeable concrete cutting chain-saw cutting assembly (500) adapted for installation upon a drive assembly (112) in exchange for a removed, different type cutting head assembly. The chainsaw cutting assembly (500) includes a housing (703) that has fasteners that releasably attach the housing (703) to a drive assembly (112) in an installed configuration. A ratio transmission (525) has a plurality of interconnected rotatable members (533, 535), each rotatable member (533, 535) having a mounting shaft (641, 643) positioned at a fixed location on the housing (703) by a bearing assembly (640, 642). The driven member (533) has a receiver that interconnects with a driveshaft (372) of the drive assembly (112) in the installed configuration whereby the driven member (533) is rotated by the drive assembly (112). The cutting chain drive member (535) operatively interconnected with a drive sprocket (707) whereby rotation of the cutting chain drive member (535) rotates the drive sprocket (707). The chainsaw cutting assembly (500) is pivotable relative to the drive assembly (112).
摘要翻译: 一种可互换的混凝土切割链锯切割组件(500),其适于安装在驱动组件(112)上,以换取移除的不同类型的切割头组件。 链锯切割组件(500)包括壳体(703),其具有将壳体(703)可释放地附接到安装构造的驱动组件(112)的紧固件。 比率传输装置(525)具有多个可互连的可旋转构件(533,553),每个可旋转构件(533,553)具有通过轴承定位在壳体(703)上的固定位置的安装轴(641,643) 组件(640,642)。 从动构件(533)具有在安装构型中与驱动组件(112)的驱动轴(372)互连的接收器,由此从动构件(533)由驱动组件(112)旋转。 切割链驱动构件(535)与驱动链轮(707)可操作地互连,由此切割链驱动构件(535)的旋转使驱动链轮(707)旋转。 链锯切割组件(500)可相对于驱动组件(112)枢转。
-
公开(公告)号:US09074424B2
公开(公告)日:2015-07-07
申请号:US13472677
申请日:2012-05-16
申请人: Andreas Jonsson , Chad Przano , Tim Ledbetter
发明人: Andreas Jonsson , Chad Przano , Tim Ledbetter
CPC分类号: E21B19/00 , E21B7/02 , E21B19/163
摘要: A rod support system has an upper gripper assembly and a lower gripper assembly. Each gripper assembly has a top plate having a first track. The first track has a first substantially arcuate portion having a first radius of curvature and a second substantially arcuate portion having a second and smaller radius of curvature. A jaw is constrained to move in a path defined by the first track. A bottom plate of the assembly has a second track that is congruent with the first track also engaging the jaw, so that the jaw is constrained to move in a path defined by the first track and the second track in cooperation. The jaws can support a rod when the jaws move from a position along the first arcuate portion of the first and second tracks to a position along the second arcuate portion of the first and second tracks.
摘要翻译: 杆支撑系统具有上夹具组件和下夹具组件。 每个夹具组件具有具有第一轨道的顶板。 第一轨道具有具有第一曲率半径的第一基本弧形部分和具有第二和较小曲率半径的第二基本上弧形部分。 钳口被限制在由第一轨道限定的路径中移动。 组件的底板具有与第一轨道一致的第二轨道,其也接合钳口,使得钳口被限制为在由第一轨道和第二轨道限定的路径中协作地移动。 当夹爪从沿着第一和第二轨道的第一弧形部分的位置移动到沿着第一和第二轨道的第二弧形部分的位置时,夹爪可以支撑杆。
-
公开(公告)号:US08888417B2
公开(公告)日:2014-11-18
申请号:US13641675
申请日:2010-04-16
申请人: Andreas Jonsson , Robert Johansson
发明人: Andreas Jonsson , Robert Johansson
CPC分类号: B23Q5/36 , B25H1/0064 , Y10T408/16 , Y10T408/17 , Y10T408/5647 , Y10T408/675 , Y10T408/6771
摘要: The present invention relates to methods and systems for automatically feeding a feeding housing (206) of a drilling device (200). The drilling device (200) includes a drill stand (202), a drilling machine (204) and a feeding housing (206). Further, the drilling machine (204), which is suspended by the feeding housing (206), includes a drill with a drilling motor for performing a drilling operation through a drilling object. The feeding unit (208) includes an electric feeding motor for feeding the feeding housing (206) along the stand (202). Further, the feeding unit (208) also includes a controller for manually influencing the feeding motor's direction of rotation, speed and feeding force.
摘要翻译: 本发明涉及用于自动馈送钻井装置(200)的进给壳体(206)的方法和系统。 钻孔装置(200)包括钻台(202),钻机(204)和进料壳体(206)。 此外,由进给壳体(206)悬挂的钻孔机(204)包括具有用于通过钻孔对象进行钻孔操作的钻孔马达的钻头。 馈送单元(208)包括用于沿着支架(202)馈送馈送壳体(206)的馈电电动机。 此外,进给单元(208)还包括用于手动影响进给马达的旋转方向,速度和进给力的控制器。
-
公开(公告)号:US20130306378A1
公开(公告)日:2013-11-21
申请号:US13472677
申请日:2012-05-16
申请人: Tim Ledbetter , Chad Przano , Andreas Jonsson
发明人: Tim Ledbetter , Chad Przano , Andreas Jonsson
IPC分类号: E21B19/00
CPC分类号: E21B19/00 , E21B7/02 , E21B19/163
摘要: A rod support system has an upper gripper assembly and a lower gripper assembly. Each gripper assembly has a top plate having a first track. The first track has a first substantially arcuate portion having a first radius of curvature and a second substantially arcuate portion having a second and smaller radius of curvature. A jaw is constrained to move in a path defined by the first track. A bottom plate of the assembly has a second track that is congruent with the first track also engaging the jaw, so that the jaw is constrained to move in a path defined by the first track and the second track in cooperation. The jaws can support a rod when the jaws move from a position along the first arcuate portion of the first and second tracks to a position along the second arcuate portion of the first and second tracks.
摘要翻译: 杆支撑系统具有上夹具组件和下夹具组件。 每个夹具组件具有具有第一轨道的顶板。 第一轨道具有具有第一曲率半径的第一基本弧形部分和具有第二和较小曲率半径的第二基本上弧形部分。 钳口被限制在由第一轨道限定的路径中移动。 组件的底板具有与第一轨道一致的第二轨道,其也接合钳口,使得钳口被限制为在由第一轨道和第二轨道限定的路径中协作地移动。 当夹爪从沿着第一和第二轨道的第一弧形部分的位置移动到沿着第一和第二轨道的第二弧形部分的位置时,夹爪可以支撑杆。
-
公开(公告)号:US20130174707A1
公开(公告)日:2013-07-11
申请号:US13819974
申请日:2011-09-01
申请人: Andreas Jonsson
发明人: Andreas Jonsson
IPC分类号: B23D47/00
摘要: A blade guard for a circular saw blade. The blade guard includes at least two pieces coupled together. The blade guard also includes at least one bottom plate having a slot formed therein for accommodating the circular saw blade and at least one top cover. Additionally, the blade guard includes a plurality of fastening rods for coupling the bottom plate with the top cover, the plurality of fastening rods further configured to secure the at least two pieces to the at least one bottom plate and the at least one top cover.
摘要翻译: 用于圆锯片的刀片防护罩。 刀片防护罩包括至少两个连接在一起的部件。 刀片护罩还包括至少一个底板,其具有形成在其中的槽,用于容纳圆锯片和至少一个顶盖。 另外,刀片防护罩包括用于将底板与顶盖联接的多个紧固杆,所述多个紧固杆进一步构造成将至少两个片固定到至少一个底板和至少一个顶盖。
-
-
-
-
-
-
-
-
-