Sensor system and methods for selective analyte detection using resonance sensor circuit
    3.
    发明授权
    Sensor system and methods for selective analyte detection using resonance sensor circuit 有权
    使用谐振传感器电路进行选择性分析物检测的传感器系统和方法

    公开(公告)号:US08364419B2

    公开(公告)日:2013-01-29

    申请号:US12424016

    申请日:2009-04-15

    IPC分类号: G01N31/00

    CPC分类号: G01N27/026

    摘要: A system, device and methods, for determining at least two analytes, wherein the system and device include at least one resonant sensor circuit that includes a sensing material that predictably affects the resonant complex impedance response of a sensor electrode. The sensing material has at least two material properties that change when the materials are exposed to two or more analytes. The system and device also include a processor that generates a multivariate sensor response pattern that is based at least in part on a change in the two material properties of the sensing material.

    摘要翻译: 一种用于确定至少两种分析物的系统,装置和方法,其中所述系统和装置包括至少一个谐振传感器电路,其包括可预测地影响传感器电极的谐振复阻抗响应的感测材料。 当材料暴露于两种或多种分析物时,传感材料具有至少两种材料性质。 该系统和装置还包括一个处理器,该处理器至少部分地基于传感材料的两种材料特性的变化而生成多变量传感器响应图案。

    Highly selective chemical and biological sensors

    公开(公告)号:US08542023B2

    公开(公告)日:2013-09-24

    申请号:US12942732

    申请日:2010-11-09

    IPC分类号: G01N27/00

    摘要: Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g. 10×, 1,000,000×) compared to other components in the mixture.

    HIGHLY SELECTIVE CHEMICAL AND BIOLOGICAL SENSORS
    7.
    发明申请
    HIGHLY SELECTIVE CHEMICAL AND BIOLOGICAL SENSORS 审中-公开
    高选择性化学和生物传感器

    公开(公告)号:US20120166095A1

    公开(公告)日:2012-06-28

    申请号:US12977568

    申请日:2010-12-23

    IPC分类号: G06F19/00 G01R27/26 B82Y99/00

    摘要: Methods and sensors for selective fluid sensing are provided. A sensor includes a resonant inductor-capacitor-resistor (LCR) circuit and a sensing material disposed over the LCR circuit. The sensing material includes a coordination compound of a ligand and a metal nanoparticle. The coordination compound has the formula: (X)n-M, where X includes an alkylamine group having the formula (R—NH2), an alkylphosphine having the formula (R3—P), an alkylphosphine oxide having the formula (R3P═O), an alkyldithiocarbamate having the formula (R2NCS2), an alkylxanthate having the formula (ROCS2), or any combination thereof, R includes an alkyl group, n is 1, 2, or 3, and M includes the metal nanoparticle of gold, silver, platinum, palladium, alloys thereof, highly conductive metal nanoparticles, or any combination thereof. The sensing material is configured to allow selective detection of at least six different analyte fluids from an analyzed fluid mixture.

    摘要翻译: 提供了选择性流体感测的方法和传感器。 传感器包括谐振电感器 - 电容器电阻(LCR)电路和设置在LCR电路上的感测材料。 感测材料包括配体和金属纳米颗粒的配位化合物。 配位化合物具有式(X)nM,其中X包括具有式(R-NH 2)的烷基胺基,具有式(R3-P)的烷基膦,具有式(R3P = O)的烷基氧化膦, 具有式(R2NCS2)的烷基二硫代氨基甲酸盐,具有式(ROCS2)的烷基马来酸盐或其任何组合,R包括烷基,n为1,2或3,并且M包括金,银,铂的金属纳米颗粒 ,钯,其合金,高导电性金属纳米颗粒或其任何组合。 感测材料被配置为允许从分析的流体混合物中选择性地检测至少六种不同的分析物流体。

    HIGHLY SELECTIVE CHEMICAL AND BIOLOGICAL SENSORS
    8.
    发明申请
    HIGHLY SELECTIVE CHEMICAL AND BIOLOGICAL SENSORS 有权
    高选择性化学和生物传感器

    公开(公告)号:US20120116683A1

    公开(公告)日:2012-05-10

    申请号:US12942732

    申请日:2010-11-09

    摘要: Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g. 10×, 1,000,000×) compared to other components in the mixture.

    摘要翻译: 提供了选择性流体感测的方法和传感器。 每个传感器包括一个涂有传感材料的谐振电感 - 电容电阻(LCR)传感器。 为了收集数据,在相对窄的频率范围(例如LCR电路的谐振频率范围)上获取阻抗谱。 可以从所获得的光谱计算多变量特征,以辨别某些流体和/或流体混合物的存在。 通过观察电路的谐振电子特性的变化来测量所用材料的介电性质,尺寸,电阻,电荷转移和其它变化的变化来检测流体的存在。 通过使用诸如主成分分析(PCA)等的数学方法,可以在彼此存在的情况下检测多种流体和混合物,即使在高湿度环境或其中一种或多种流体具有显着更高浓度的环境中 (例如10×1,000,000×)与混合物中的其他成分相比。