Devices and methods for the treatment of cancer
    2.
    发明授权
    Devices and methods for the treatment of cancer 有权
    用于治疗癌症的装置和方法

    公开(公告)号:US08647603B2

    公开(公告)日:2014-02-11

    申请号:US13314239

    申请日:2011-12-08

    IPC分类号: A61K51/00 A61M36/14

    摘要: The invention relates to the treatment of cancer. In particular the invention relates to an internal therapeutic product comprising: (i) an anti-cancer component selected from one or both of: a radionucleotide, a cytotoxic drug; and (ii) a silicon component selected from one or more of: resorbable silicon, biocompatible silicon, bioactive silicon, porous silicon, polycrystalline silicon, amorphous silicon, and bulk crystalline silicon, the internal therapeutic product being for the treatment of cancer.

    摘要翻译: 本发明涉及癌症的治疗。 特别地,本发明涉及内部治疗产品,其包含:(i)选自以下的一种或两种的抗癌成分:放射性核苷酸,细胞毒性药物; 和(ii)选自以下的一种或多种的硅成分:可再吸收硅,生物相容性硅,生物活性硅,多孔硅,多晶硅,非晶硅和体结晶硅,所述内部治疗产品用于治疗癌症。

    Body fluid collection and analysis
    6.
    发明申请
    Body fluid collection and analysis 审中-公开
    体液收集和分析

    公开(公告)号:US20060052681A1

    公开(公告)日:2006-03-09

    申请号:US11187019

    申请日:2005-07-22

    IPC分类号: A61B5/00

    摘要: The invention relates to attachable body fluid collection devices, each comprising at least one storage structure for, when in use, storing a body fluid sample secreted by a body fluid secreting surface. The or at least one of the storage structure comprises silicon. Particular emphasis is placed on sweat patches and techniques for analyzing sweat.

    摘要翻译: 本发明涉及可附接的体液收集装置,每个装置包括至少一个存储结构,用于在使用时储存由体液分泌表面分泌的体液样品。 存储结构中的至少一个包括硅。 特别强调用于分析汗水的汗水补丁和技术。

    Porous silicon drug-eluting particles
    7.
    发明授权
    Porous silicon drug-eluting particles 有权
    多孔硅药物洗脱颗粒

    公开(公告)号:US09023896B2

    公开(公告)日:2015-05-05

    申请号:US12773127

    申请日:2010-05-04

    摘要: The invention provides a biodegradable drug-eluting particle useful for the delivery of diagnostic or therapeutic agents. In certain embodiments, the drug-eluting particle of the invention comprises a biodegradable porous silicon body, a reservoir formed within the porous silicon body having at least one opening to an exterior of the body, wherein the reservoir contains a therapeutic or diagnostic agent, and an agent-permeable seal disposed over the at least one opening. The invention further provides a method for treating a patient to obtain a desired local or systemic physiological or pharmacological effect comprising administering a sustained release drug delivery particle of the invention. The invention also provides methods of fabricating a drug-eluting particle for releasing therapeutic agents.

    摘要翻译: 本发明提供了可用于递送诊断或治疗剂的可生物降解的药物洗脱颗粒。 在某些实施方案中,本发明的药物洗脱颗粒包括可生物降解的多孔硅体,形成在多孔硅体内的储存器,其具有至少一个开口到本体的外部,其中储存器包含治疗剂或诊断剂,以及 设置在所述至少一个开口上方的渗透剂的密封件。 本发明进一步提供了一种治疗患者以获得所需局部或全身生理或药理作用的方法,包括施用本发明的缓释药物递送颗粒。 本发明还提供了制备用于释放治疗剂的药物洗脱颗粒的方法。

    POROUS SILICON DRUG-ELUTING PARTICLES
    10.
    发明申请
    POROUS SILICON DRUG-ELUTING PARTICLES 有权
    多孔硅胶药物颗粒

    公开(公告)号:US20100278931A1

    公开(公告)日:2010-11-04

    申请号:US12773127

    申请日:2010-05-04

    IPC分类号: A61K9/14 A61K31/58 A61P27/02

    摘要: The invention provides a biodegradable drug-eluting particle useful for the delivery of diagnostic or therapeutic agents. In certain embodiments, the drug-eluting particle of the invention comprises a biodegradable porous silicon body, a reservoir formed within the porous silicon body having at least one opening to an exterior of the body, wherein the reservoir contains a therapeutic or diagnostic agent, and an agent-permeable seal disposed over the at least one opening. The invention further provides a method for treating a patient to obtain a desired local or systemic physiological or pharmacological effect comprising administering a sustained release drug delivery particle of the invention. The invention also provides methods of fabricating a drug-eluting particle for releasing therapeutic agents

    摘要翻译: 本发明提供了可用于递送诊断或治疗剂的可生物降解的药物洗脱颗粒。 在某些实施方案中,本发明的药物洗脱颗粒包括可生物降解的多孔硅体,形成在多孔硅体内的储存器,其具有至少一个开口到本体的外部,其中储存器包含治疗剂或诊断剂,以及 设置在所述至少一个开口上方的渗透剂的密封件。 本发明进一步提供了一种治疗患者以获得所需局部或全身生理或药理作用的方法,包括施用本发明的缓释药物递送颗粒。 本发明还提供了制备用于释放治疗剂的药物洗脱颗粒的方法