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    METHOD OF EXPANDING DOUBLE NEGATIVE T CELLS
    1.
    发明申请
    METHOD OF EXPANDING DOUBLE NEGATIVE T CELLS 有权
    扩展双重负性T细胞的方法

    公开(公告)号：US20090098095A1

    公开(公告)日：2009-04-16

    申请号：US12093492

    申请日：2006-11-20

    申请人： Li Zhang ,  Mei Han ,  Pouneh Dokouhaki

    发明人： Li Zhang ,  Mei Han ,  Pouneh Dokouhaki

    IPC分类号： A61K35/12 ,  C12N5/06 ,  C12N5/08

    CPC分类号： A61K35/17 ,  C12N5/0636 ,  C12N2501/23 ,  C12N2501/2302 ,  C12N2501/2304 ,  C12N2501/515

    摘要： A method of expanding double negative T cells in culture is described. The method comprises (a) providing a starting sample comprising DN T cells or precursors thereof; (b) substantially depleting CD8+ and CD4+ T cells from the starting sample; (c) culturing the sample from step (b) with an immobilized T cell mitogen in a culture medium comprising an agent that can stimulate DN T cell growth; (d) washing the cells obtained in step (c) and resuspending in a culture medium comprising the agent without the T cell mitogen; and (e) washing the cells obtained in step (d) and resuspending in a culture medium comprising the agent and a soluble T cell mitogen. The DN T cells obtained by the method are useful in a variety of applications including the treatment of cancer, infectious diseases, graft versus host disease and autoimmune disease.

    摘要翻译： 描述了在培养中扩增双重负T细胞的方法。 该方法包括（a）提供包含DN T细胞或其前体的起始样品; （b）从起始样品中大量消耗CD8 +和CD4 + T细胞; （c）在包含可刺激DN T细胞生长的试剂的培养基中培养来自步骤（b）的样品与固定的T细胞丝裂原; （d）洗涤步骤（c）中获得的细胞，并重新悬浮在包含不含T细胞丝裂原的试剂的培养基中; 和（e）洗涤步骤（d）中获得的细胞，并重新悬浮于包含该试剂和可溶性T细胞丝裂原的培养基中。 通过该方法获得的DN T细胞可用于各种应用，包括治疗癌症，感染性疾病，移植物抗宿主病和自身免疫性疾病。

    Method of expanding double negative T cells
    2.
    发明授权
    Method of expanding double negative T cells 有权
    扩大双阴性T细胞的方法

    公开(公告)号：US09018004B2

    公开(公告)日：2015-04-28

    申请号：US12093492

    申请日：2006-11-20

    申请人： Li Zhang ,  Mei Han ,  Pouneh Dokouhaki

    发明人： Li Zhang ,  Mei Han ,  Pouneh Dokouhaki

    IPC分类号： C12N5/0783

    CPC分类号： A61K35/17 ,  C12N5/0636 ,  C12N2501/23 ,  C12N2501/2302 ,  C12N2501/2304 ,  C12N2501/515

    摘要： A method of expanding double negative T cells in culture is described. The method comprises (a) providing a starting sample comprising DN T cells or precursors thereof; (b) substantially depleting CD8+ and CD4+ T cells from the starting sample; (c) culturing the sample from step (b) with an immobilized T cell mitogen in a culture medium comprising an agent that can stimulate DN T cell growth; (d) washing the cells obtained in step (c) and resuspending in a culture medium comprising the agent without the T cell mitogen; and (e) washing the cells obtained in step (d) and resuspending in a culture medium comprising the agent and a soluble T cell mitogen. The DN T cells obtained by the method are useful in a variety of applications including the treatment of cancer, infectious diseases, graft versus host disease and autoimmune disease.

    摘要翻译： 描述了在培养中扩增双重负T细胞的方法。 该方法包括（a）提供包含DN T细胞或其前体的起始样品; （b）从起始样品中大量消耗CD8 +和CD4 + T细胞; （c）在包含可刺激DN T细胞生长的试剂的培养基中培养来自步骤（b）的样品与固定的T细胞丝裂原; （d）洗涤步骤（c）中获得的细胞，并重新悬浮在包含不含T细胞丝裂原的试剂的培养基中; 和（e）洗涤步骤（d）中获得的细胞，并重新悬浮于包含该试剂和可溶性T细胞丝裂原的培养基中。 通过该方法获得的DN T细胞可用于各种应用，包括治疗癌症，感染性疾病，移植物抗宿主病和自身免疫性疾病。

    Electric steam iron
    3.
    发明授权
    Electric steam iron 有权

    公开(公告)号：US12043952B2

    公开(公告)日：2024-07-23

    申请号：US18102894

    申请日：2023-01-30

    申请人： Li Zhang

    发明人： Li Zhang

    IPC分类号： D06F75/16 ,  D06F75/20 ,  D06F75/24 ,  D06F75/26

    CPC分类号： D06F75/16 ,  D06F75/20 ,  D06F75/24 ,  D06F75/265

    摘要： The present disclosure provides an electric steam iron, comprising: a housing provided with a water injection unit, the water injection unit being configured to injecting water; a heating unit comprising a heating shell and a heating element, a first chamber and a second chamber being set in the heating shell, the first chamber is configured for receiving water from the water injection unit; the heating shell is in the first chamber and heats the water in the first chamber to generate steam; the second chamber is connected with the first chamber to receive steam in the first chamber; a first lead-out hole is defined in a bottom of the first chamber; a cover is provided to cover a bottom of the heating shell a steam ironing plate, a steam channel is on the steam ironing plate, the steam channel being distributed on the steam ironing plate in a roundabout manner.

    Balance beam
    4.
    外观设计
    Balance beam 有权

    公开(公告)号：USD1011451S1

    公开(公告)日：2024-01-16

    申请号：US29897344

    申请日：2023-07-13

    申请人： Li Zhang

    设计人： Li Zhang

    摘要： FIG. 1 is a front, right and top perspective view of a balance beam, showing my design.
    FIG. 2 is a rear, left and bottom perspective view thereof.
    FIG. 3 is a front elevation view thereof.
    FIG. 4 is a rear elevation view thereof.
    FIG. 5 is an enlarged left side elevation view thereof.
    FIG. 6 is an enlarged right side elevation view thereof.
    FIG. 7 is a top plan view thereof.
    FIG. 8 is a bottom plan view thereof.
    FIG. 9 is an enlarged view of detail 9 in FIG. 1; and,
    FIG. 10 is an enlarged view of detail 10 in FIG. 2.
    The broken lines depict portions of the balance beam that form no part of the claimed design. The dot-dash broken lines in FIGS. 1, 2, 9, and 10 depict the boundaries of the enlargements that form no part of the claimed design.

    Stackable storage unit
    5.
    外观设计
    Stackable storage unit 有权

    公开(公告)号：USD1007331S1

    公开(公告)日：2023-12-12

    申请号：US29881142

    申请日：2022-12-28

    申请人： Li Zhang

    设计人： Li Zhang

    摘要： FIG. 1 is a bottom perspective view of stackable storage unit, showing my new design;
    FIG. 2 is a front view thereof;
    FIG. 3 is a rear view thereof;
    FIG. 4 is a left side view thereof;
    FIG. 5 is a right side view thereof;
    FIG. 6 is a top view thereof; and,
    FIG. 7 is a bottom view thereof.
    The broken lines in the drawings illustrate the portions of the stackable storage unit, which form no part of the claimed design.

    METHOD AND DEVICE FOR MEASUREMENT RESTRICTION
    6.
    发明申请
    METHOD AND DEVICE FOR MEASUREMENT RESTRICTION 审中-公开

    公开(公告)号：US20200228269A1

    公开(公告)日：2020-07-16

    申请号：US16650577

    申请日：2018-05-10

    申请人： Li Zhang ,  Haitao Li

    发明人： Li Zhang ,  Haitao Li

    IPC分类号： H04L5/00 ,  H04W36/00 ,  H04W24/10 ,  H04W74/00 ,  H04W72/04 ,  H04W76/27

    摘要： Embodiments of the present disclosure provide methods, devices and a computer readable medium for a restriction on a measurement for a neighbor cell. According to a method implemented by a network device in a communication system, the network device determines a neighbor cell on a frequency layer capable of cell reference signal (CRS) muting. A cell reference signal in the neighbor cell is transmitted on a predetermined physical resource if the neighbor cell enables CRS muting. In response to the determination, the network device transmits measurement restriction information to a terminal device in a cell of the network device. The measurement restriction information indicates that a radio resource management (RRM) measurement for any neighbor cell on the frequency layer is restricted to be performed on the predetermined physical resource. The embodiments of the present disclosure improve a measurement for a neighbor cell.

    BZ glaze enamel painting material composition and painting method
    7.
    发明授权
    BZ glaze enamel painting material composition and painting method 有权

    公开(公告)号：US10577506B2

    公开(公告)日：2020-03-03

    申请号：US16019549

    申请日：2018-06-27

    申请人： Li Zhang

    发明人： Li Zhang

    IPC分类号： C09D5/06 ,  C09D5/14 ,  C09D1/00 ,  C09D17/00

    摘要： Provided are a BZ glaze enamel painting material composition and a painting method. The composition is a painting material composition composed of natural mineral pigment powder, synthetic resin, and vinyl acetate-acrylate added with a color glaze, a white toning glaze, and a colorless toning glaze at different percentages. The painting method that uses the composition includes the steps of preparing painting canvas, forming bottom, and making picture. In the step of making picture, a suitable amount of BZ glaze enamel painting material composition is prepared according to the size of the painting canvas and, and after being sufficiently stirred, added with temperature-resistant minerals and water according to predetermined weight ratios to respectively form red glaze, yellow glaze, blue glaze, green glaze, purple glaze, orange glaze, and cyan glaze, followed by mixing to product a BZ painting artwork exhibiting, in the entirety thereof, an irregular pattern.

    Method and apparatus for carrier aggregation
    8.
    发明授权
    Method and apparatus for carrier aggregation 有权

    公开(公告)号：US10051633B2

    公开(公告)日：2018-08-14

    申请号：US14419301

    申请日：2012-08-03

    申请人： Li Zhang ,  Hai Peng Lei ,  Chun Hai Yao

    发明人： Li Zhang ,  Hai Peng Lei ,  Chun Hai Yao

    IPC分类号： H04W72/04 ,  H04L5/14 ,  H04B7/0456 ,  H04B7/06 ,  H04L1/18 ,  H04L5/00

    摘要： A method including: using first information and second information to determine a code book size, said first information including information for at least one first subframe of at least one cell for which feedback information is to be provided, said at least one first subframe is prior to subframe n and second information for at least one second subframe of at least one cell for which feedback information is to be provided, said at least one second subframe being after said subframe n; and using said code book size for providing feedback information.