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    Substituted amides
    1.
    发明授权
    Substituted amides 失效
    取代酰胺

    公开(公告)号：US07576239B2

    公开(公告)日：2009-08-18

    申请号：US12008728

    申请日：2008-01-14

    申请人： Linus S. Lin ,  William K. Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

    发明人： Linus S. Lin ,  William K. Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

    IPC分类号： C07C233/05 ,  C07D213/02 ,  A61K31/44

    CPC分类号： C07D213/64 ,  C07C255/60 ,  C07C275/24 ,  C07C2601/04

    摘要： Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.

    摘要翻译： 结构式（I）的新型化合物是大麻素-1（CB1）受体的拮抗剂和/或反向激动剂，可用于治疗，预防和抑制由CB1受体介导的疾病。 本发明的化合物可用作治疗精神病，记忆缺陷，认知障碍，偏头痛，神经病，包括多发性硬化和神经 - 巴利综合征的神经炎症性疾病以及病毒性脑炎的炎症性后遗症，脑血管 事故和头部创伤，焦虑症，压力，癫痫，帕金森病，运动障碍和精神分裂症。 这些化合物还可用于治疗药物滥用障碍，治疗肥胖或进食障碍，以及治疗哮喘，便秘，慢性肠假性梗阻和肝硬化。

    Substituted amides
    2.
    发明申请
    Substituted amides 失效
    取代酰胺

    公开(公告)号：US20080194645A1

    公开(公告)日：2008-08-14

    申请号：US12008728

    申请日：2008-01-14

    申请人： Linus S. Lin ,  William K. Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

    发明人： Linus S. Lin ,  William K. Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

    IPC分类号： A61K31/44 ,  C07D211/86 ,  A61P25/06 ,  A61P25/28

    CPC分类号： C07D213/64 ,  C07C255/60 ,  C07C275/24 ,  C07C2601/04

    摘要： Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.

    摘要翻译： 结构式（I）的新型化合物是大麻素-1（CB1）受体的拮抗剂和/或反向激动剂，可用于治疗，预防和抑制由CB1受体介导的疾病。 本发明的化合物可用作治疗精神病，记忆缺陷，认知障碍，偏头痛，神经病，包括多发性硬化和神经 - 巴利综合征的神经炎症性疾病以及病毒性脑炎的炎症性后遗症，脑血管 事故和头部创伤，焦虑症，压力，癫痫，帕金森病，运动障碍和精神分裂症。 这些化合物还可用于治疗药物滥用障碍，治疗肥胖或进食障碍，以及治疗哮喘，便秘，慢性肠假性梗阻和肝硬化。

    Substituted amides
    3.
    发明授权
    Substituted amides 有权

    公开(公告)号：US07348456B2

    公开(公告)日：2008-03-25

    申请号：US10538395

    申请日：2003-12-15

    申请人： Linus S. Lin ,  William K. Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

    发明人： Linus S. Lin ,  William K. Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

    IPC分类号： C07C233/05 ,  C07D213/02 ,  A61K31/44

    CPC分类号： C07D213/64 ,  C07C255/60 ,  C07C275/24 ,  C07C2601/04

    摘要： Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.

    Substituted amides
    4.
    发明申请
    Substituted amides 有权

    公开(公告)号：US20060106071A1

    公开(公告)日：2006-05-18

    申请号：US10538395

    申请日：2003-12-15

    申请人： Linus Lin ,  William Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

    发明人： Linus Lin ,  William Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

    IPC分类号： A61K31/44 ,  A61K31/277 ,  C07D213/63 ,  C07C255/50

    CPC分类号： C07D213/64 ,  C07C255/60 ,  C07C275/24 ,  C07C2601/04

    摘要： Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.

    Measurement Device
    5.
    发明申请
    Measurement Device 审中-公开

    公开(公告)号：US20200221936A1

    公开(公告)日：2020-07-16

    申请号：US16830166

    申请日：2020-03-25

    申请人： Muruga Raj ,  Sanjeev Kumar

    发明人： Muruga Raj ,  Sanjeev Kumar

    IPC分类号： A61B1/00 ,  A61B1/015

    摘要： Various embodiments include an endoscopic device. A sheath may enclose the device and may thereby guard against environmental contamination. The sheath may include one or more channels for transmission of instruments and/or solution to and from the body. The sheath may be disposable. A stopper unit may reduce fluid leakage from inside a body cavity during a procedure. The stopper unit may include a serrated outer contour to assist in catching at a body orifice. The stopper unit may have a perforable inner barrier designed to reseal about a probing portion inserted through the stopper unit.

    Messaging system with content-based dynamic menu generation
    9.
    发明授权
    Messaging system with content-based dynamic menu generation 有权
    基于内容的动态菜单生成的消息传递系统

    公开(公告)号：US09292834B2

    公开(公告)日：2016-03-22

    申请号：US11346410

    申请日：2006-02-02

    申请人： Labhesh Patel ,  Sanjeev Kumar ,  Mukul Jain ,  Joseph F. Khouri

    发明人： Labhesh Patel ,  Sanjeev Kumar ,  Mukul Jain ,  Joseph F. Khouri

    IPC分类号： G06Q10/10 ,  H04L12/58 ,  H04M3/533

    CPC分类号： G06Q10/107 ,  H04L51/066 ,  H04L51/36 ,  H04M3/53333 ,  H04M2203/355 ,  H04M2203/4509

    摘要： A unified messaging system for an enterprise includes a messaging module operable to store a message sent by a first user to a second user in a first media type, and to deliver the message to the second user in either the first type or a second media type. A natural language speech parsing (NLSP) module coupled with the messaging module is operable to detect an actionable item contained within the message, the messaging module dynamically modifying a response menu to include an option corresponding to the actionable item, and then presenting the modified response menu to the second user concurrent with or following delivery of the message. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

    摘要翻译： 用于企业的统一消息系统包括消息传送模块，其可操作以将第一用户发送的消息以第一媒体类型存储到第二用户，并且以第一类型或第二媒体类型将消息传递给第二用户 。 与消息传递模块耦合的自然语言语音解析（NLSP）模块可操作以检测包含在消息内的可操作项目，消息传递模块动态地修改响应菜单以包括与可操作项目相对应的选项，然后呈现修改的响应 到第二个用户的菜单，同时发送或在发送消息之后。 提交它的理解是，它不会用于解释或限制权利要求的范围或含义。

    Integrated alerting
    10.
    发明授权
    Integrated alerting 有权
    集成警报

    公开(公告)号：US09042542B2

    公开(公告)日：2015-05-26

    申请号：US11686838

    申请日：2007-03-15

    申请人： Shmuel Shaffer ,  Mukul Jain ,  Labhesh Patel ,  Sanjeev Kumar

    发明人： Shmuel Shaffer ,  Mukul Jain ,  Labhesh Patel ,  Sanjeev Kumar

    IPC分类号： H04M1/00 ,  H04M15/06

    CPC分类号： H04M15/06

    摘要： In a wide-area communication system, users or numbers in the system to be alerted are ranked so to improve the efficiency of the alert calls. Rankings are based on various factors, including whether two or more users are on the same active call, whether a user is on an active call, how recently a user ended a call, and whether a user recently missed a call. Within rankings, there may be multiple callers or numbers. These users may further be ranked, such as by determining which caller is expected to end a call first based on the current elapsed time of the call and the average call duration for that user or number.

    摘要翻译： 在广域通信系统中，要提醒的系统中的用户或号码被排序，以提高警报呼叫的效率。 排名基于各种因素，包括两个或多个用户是否处于相同的活动呼叫，用户是否处于活动呼叫，用户最近结束呼叫以及用户最近是否已经接通呼叫。 在排名中，可能有多个呼叫者或号码。 这些用户可以进一步排名，例如通过基于呼叫的当前经过时间和该用户或号码的平均呼叫持续时间来确定预期哪个呼叫者首先结束呼叫。