公开(公告)号：US08802929B2

公开(公告)日：2014-08-12

申请号：US13319534

申请日：2010-05-12

申请人： Lizhong Xiong ,  Kabin Xie ,  Xin Hou

发明人： Lizhong Xiong ,  Kabin Xie ,  Xin Hou

IPC分类号： A01H5/00 ,  C12N15/82 ,  C12N15/113

CPC分类号： C12N15/8287 ,  A01H5/02 ,  A01H6/1424 ,  C12N15/8262

摘要： A rice microRNA, miR164 gene, that controls plant root system development and fertility, is obtained through gene isolation, cloning and function verification. Uses of a nucleic acid fragment comprising miR164, which fragment may confer a transformed plant with the ability to increase root number and to alter fertility, wherein the said nucleic acid fragment is selected from one of the following nucleotide sequences: 1) a DNA sequence as shown in SEQ ID NO: 1; 2) a RNA sequence as shown in SEQ ID NO:2; or 3) the conserved sequence of miR164 having the same function as 1) or 2). The nucleotide sequence containing the precursor of miR164 is ligated with an exogenous promoter and introduced into rice to obtain transgenic rice plants which has large root systems but became infertile. The fertility can be restored by external application of phytohormones.

摘要翻译： 通过基因分离，克隆和功能验证获得了控制植物根系发育和育性的水稻microRNA，miR164基因。 使用包含miR164的核酸片段，该片段可赋予具有增加根数和改变生育能力的能力的转化植物，其中所述核酸片段选自下列核苷酸序列之一：1）将DNA序列作为 如SEQ ID NO：1所示; 2）如SEQ ID NO：2所示的RNA序列; 或3）具有与1）或2）相同功能的miR164的保守序列。 将含有miR164前体的核苷酸序列与外源启动子连接，并引入水稻中以获得具有大根系但变得不育的转基因水稻。 生殖力可以通过植物激素的外部应用来恢复。

公开(公告)号：US20120102598A1

公开(公告)日：2012-04-26

申请号：US13319534

申请日：2010-05-12

申请人： Lizhong Xiong ,  Kabin Xie ,  Xin Hou

发明人： Lizhong Xiong ,  Kabin Xie ,  Xin Hou

IPC分类号： A01H1/06 ,  C12N5/10 ,  C12N15/82

CPC分类号： C12N15/8287 ,  A01H5/02 ,  A01H6/1424 ,  C12N15/8262

摘要： A rice microRNA, miR164 gene, that controls plant root system development and fertility, is obtained through gene isolation, cloning and function verification. Uses of a nucleic acid fragment comprising miR164, which fragment may confer a transformed plant with the ability to increase root number and to alter fertility, wherein the said nucleic acid fragment is selected from one of the following nucleotide sequences: 1) a DNA sequence as shown in SEQ ID NO: 1; 2) a RNA sequence as shown in SEQ ID NO:2; or 3) the conserved sequence of miR164 having the same function as 1) or 2). The nucleotide sequence containing the precursor of miR164 is ligated with an exogenous promoter and introduced into rice to obtain transgenic rice plants which has large root systems but became infertile. The fertility can be restored by external application of phytohormones.

摘要翻译： 通过基因分离，克隆和功能验证获得了控制植物根系发育和育性的水稻microRNA，miR164基因。 使用包含miR164的核酸片段，该片段可赋予具有增加根数和改变生育能力的能力的转化植物，其中所述核酸片段选自以下核苷酸序列之一：1）DNA序列作为 如SEQ ID NO：1所示; 2）如SEQ ID NO：2所示的RNA序列; 或3）具有与1）或2）相同功能的miR164的保守序列。 将含有miR164前体的核苷酸序列与外源启动子连接，并引入水稻中以获得具有大根系但变得不育的转基因水稻。 生殖力可以通过植物激素的外部应用来恢复。

公开(公告)号：US20120102591A1

公开(公告)日：2012-04-26

申请号：US13264620

申请日：2010-04-14

申请人： Lizhong Xiong ,  Xin Hou ,  Zhuyun Qi

发明人： Lizhong Xiong ,  Xin Hou ,  Zhuyun Qi

IPC分类号： C12N15/82

CPC分类号： C07K14/415 ,  C12N15/8273

摘要： The present invention pertains to the field of rice genetic engineering. Specifically, the present invention relates to a rice OsNHAD gene that enhances tolerance to salt stress, which was obtained through gene isolation, cloning and function verification, and also to use of the gene in genetic improvement of salt tolerance of rice. Said gene is selected from one of the following nucleotide sequences: 1) the nucleotide sequence from positions 60 to 1649 of SEQ NO: 1 in the Sequence Listing; or 2) a nucleotide sequence that encodes the same protein as that encoded by 1). Transgenic rice plants obtained by introducing into rice the nucleotide sequence comprising OsNHAD gene operably ligated with exogenous promoter had enhanced salt tolerance.

摘要翻译： 本发明涉及水稻基因工程领域。 具体地，本发明涉及通过基因分离，克隆和功能验证获得的增强耐盐胁迫的水稻OsNHAD基因，并且还涉及该基因在水稻耐盐性遗传改良中的应用。 所述基因选自以下核苷酸序列之一：1）序列表中SEQ ID NO：1的位置60至1649的核苷酸序列; 或2）编码与1）编码的蛋白相同的蛋白质的核苷酸序列。 通过引入水稻获得的转基因水稻，包含可操作地与外源启动子连接的OsNHAD基因的核苷酸序列具有增强的耐盐性。

公开(公告)号：US08802818B2

公开(公告)日：2014-08-12

申请号：US13486502

申请日：2012-06-01

申请人： William D. Lubell ,  Sylvain Chemtob ,  Terence E. Hebert ,  Audrey Claing ,  Stephane Laporte ,  Carine B. Bourguet ,  Eugenie Goupil ,  Xin Hou ,  Danae Tassy

发明人： William D. Lubell ,  Sylvain Chemtob ,  Terence E. Hebert ,  Audrey Claing ,  Stephane Laporte ,  Carine B. Bourguet ,  Eugenie Goupil ,  Xin Hou ,  Danae Tassy

IPC分类号： A61K38/00 ,  A61K38/06 ,  C07K2/00 ,  C07K4/00 ,  C07K5/00 ,  C07K7/00 ,  C07K14/00 ,  C07K16/00 ,  C07K17/00 ,  A61K51/00

CPC分类号： C07K5/1024 ,  A61K38/00 ,  C07K5/0812 ,  C12Q1/485

摘要： Prostaglandin-F2 alpha (PGF2α) receptor (FP) modulators of formula I, as well as the use of PGF2α receptor modulators for the treatment of conditions associated with FP activity such as preterm labor and colorectal cancer, are disclosed.

摘要翻译： 公开了式I的前列腺素F2α（PGF2α）受体（FP）调节剂，以及PGF2α受体调节剂用于治疗与FP活性相关的病症如早产和结肠直肠癌的用途。

公开(公告)号：US20130187915A1

公开(公告)日：2013-07-25

申请号：US13355364

申请日：2012-01-20

申请人： Ken Lee ,  Xin Hou

发明人： Ken Lee ,  Xin Hou

IPC分类号： G06T17/00

CPC分类号： G06T9/001 ,  G06T17/20

摘要： Described are computer-based methods and apparatuses, including computer program products, for compressing three dimensional data of a scene. Data is received comprising (i) three dimensional data of a scene, and (ii) depth data associated with the three dimensional data. A triangle mesh is generated based on the three dimensional data, the triangle mesh comprising a plurality of triangles, each triangle including three vertices and three edges connecting the three vertices. For each edge in the triangle mesh, a metric is calculated for the edge based on data from the depth data associated with the edge, a length of the edge, and a curvature of the edge. A set of edges is collapsed based on a metric associated with each edge in the set of edges to generate a compressed triangle mesh.

摘要翻译： 描述了用于压缩场景的三维数据的基于计算机的方法和装置，包括计算机程序产品。 接收数据包括（i）场景的三维数据，和（ii）与三维数据相关联的深度数据。 基于三维数据生成三角形网格，三角形网格包括多个三角形，每个三角形包括连接三个顶点的三个顶点和三个边。 对于三角形网格中的每个边缘，基于与边缘相关联的深度数据，边缘的长度和边缘的曲率的数据计算边缘的度量。 基于与该组边缘中的每个边缘相关联的度量来折叠一组边缘以生成压缩三角形网格。

公开(公告)号：US08766979B2

公开(公告)日：2014-07-01

申请号：US13355364

申请日：2012-01-20

申请人： Ken Lee ,  Xin Hou

发明人： Ken Lee ,  Xin Hou

IPC分类号： G06T15/30

CPC分类号： G06T9/001 ,  G06T17/20

摘要： Described are computer-based methods and apparatuses, including computer program products, for compressing three dimensional data of a scene. Data is received comprising (i) three dimensional data of a scene, and (ii) depth data associated with the three dimensional data. A triangle mesh is generated based on the three dimensional data, the triangle mesh comprising a plurality of triangles, each triangle including three vertices and three edges connecting the three vertices. For each edge in the triangle mesh, a metric is calculated for the edge based on data from the depth data associated with the edge, a length of the edge, and a curvature of the edge. A set of edges is collapsed based on a metric associated with each edge in the set of edges to generate a compressed triangle mesh.

摘要翻译： 描述了用于压缩场景的三维数据的基于计算机的方法和装置，包括计算机程序产品。 接收数据包括（i）场景的三维数据，和（ii）与三维数据相关联的深度数据。 基于三维数据生成三角形网格，三角形网格包括多个三角形，每个三角形包括连接三个顶点的三个顶点和三个边。 对于三角形网格中的每个边缘，基于与边缘相关联的深度数据，边缘的长度和边缘的曲率的数据计算边缘的度量。 基于与该组边缘中的每个边缘相关联的度量来折叠一组边缘以生成压缩三角形网格。