Abstract:
Compounds of the formula where R1, R2, R3 and R4 have the meaning stated in the description, and a process for preparing them are described. The compounds are suitable as starting material for synthesizing substances which are active against tumors.
Abstract:
A process for preparing high-purity isobutyramide which comprises reacting isobutyryl chloride in toluene or xylene at -15.degree. to 30.degree. C. with ammonia is described.
Abstract:
Compounds of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meaning stated in the description, and a process for preparing them are described. The compounds are suitable as starting material for synthesizing substances which are active against tumors.
Abstract:
The compound Me.sub.2 Val--Val--MeVal--Pro--Pro--NHBzl.multidot.HCl is described. It is prepared from Z--Val--Val--MeVal--Pro--OR.sup.1 where Z and R.sup.1 have the meanings stated in the description. The compound shows antineoplastic activity.
Abstract:
A process for the preparation of a tetralin derivative of the formula ##STR1## where X is a --CH.sub.2 --, --CH(OH)-- or --CO-- group, R.sup.1 is one of the groups --COCH.sub.3, --CH(OR.sup.3).sub.2 or --CHO, R.sup.2 is hydrogen or methyl and R.sup.3 is alkyl of 1 to 4 carbon atoms, by electrochemical oxidation of a compound of the formula ##STR2## where R.sup.4 is methyl or ethyl and X and R.sup.2 have the abovementioned meanings, and novel tetralin derivatives.
Abstract:
Cycloalkylidene derivatives of the general formulae Ia to Ic ##STR1## where the dashed line is a possible additional chemical bond, the radicals R.sup.1 are identical or different C.sub.1 -C.sub.4 -alkenyl groups, R.sup.2 and R.sup.3 are each methyl or ethyl, R.sup.4 is hydrogen or one of the radicals R.sup.1, X is oxygen, methylene or a chemical bond, m is from 0 to 3 or, when X is methylene, is from 1 to 3, or, when X is methylene and R.sup.1 is methyl, is from 2 to 3 and n is from 0 to 3, are used as fragrance materials.
Abstract:
N,N'-disubstituted piperazines of the general formula I ##STR1## where the group is unsaturated (.dbd.) or saturated (--) and the substituents R.sup.1, R.sup.2 and A have the following meanings:A is --, --CH.dbd., --CH.sub.2 --, --CH.sub.2 --CH.sub.2 --,R.sup.1 is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, alkylcycloalkyl, cycloalkenylalkyl, alkylcycloalkenyl, bicycloalkyl, bicycloalkylalkyl or alkylbicycloalkyl, these radicals being unsubstituted or substituted by hydroxy, halogen, alkoxy or trialkylsilyl,R.sup.1 is further heterocycloalkyl with oxygen and/or sulfur, heterocycloalkylmethyl with oxygen and/or sulfur, alkyl-substituted heterocycloalkylmethyl with oxygen and/or sulfur, andR.sup.2 is alkyl, alkoxy, trimethylsilyl, cycloalkyl, alkylthio,and plant-physiologically tolerated salts thereof, and fungicides containing these compounds.
Abstract:
s-Triazine compounds which can be used as sunscreen agents are prepared in a technically simpler manner by a process in which an ester of a branched alkanoic acid with a saturated aliphatic alcohol or, if appropriate, a mixture of such alcohols is used as the solvent in the reaction of a cyanuric halide with a p-aminobenzoate.
Abstract:
The invention is directed to a process for preparing 3,7-dialkylxanthines of the formula I ##STR1## (R.sup.1 and R.sup.2 denote C.sub.1 -C.sub.4 -alkyl) by the reaction of 4-amino-imidazolecarboxamide-(5) of the formula II ##STR2## with an alkali cyanate in aqueous solution at a pH of from 3 to 5 followed by cyclization of the resulting urea derivative at a pH of from 8 to 14.
Abstract:
4-Substituted but-3-ene-1-carboxylic acids and their esters R.sup.1 R.sup.2 C.dbd.CH--CH.sub.2 --CO--O--R.sup.3 (I, where R.sup.1 is an organic radical, R.sup.2 is H or R.sup.1, or R.sup.1 and R.sup.2 together form a 5-membered to 20-membered ring, and R.sup.3 is H or lower alkyl) are prepared by carbonylation of R.sup.1 R.sup.2 C(OH)--CH.dbd.CH.sub.2 (II) in the presence of an alcohol R.sup.3' --OH (III, where R.sup.3' is lower alkyl) or, for the preparation of the acids I alone, in the absence of an alcohol III, at from 50.degree. to 150.degree. C. and under from 200 to 700 bar, using a complex of a palladium halide and a tertiary organic phosphine.