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公开(公告)号:US20140018893A1
公开(公告)日:2014-01-16
申请号:US13980284
申请日:2011-11-08
IPC分类号: A61N1/05
CPC分类号: A61N1/05 , A61B5/00 , A61B5/042 , A61B2560/0406 , A61B2562/12 , A61F2/0077 , A61L27/18 , A61L27/50 , A61L2400/12 , A61L2400/18 , A61N1/056 , A61N1/375 , C08L75/04 , C08L83/04
摘要: An implantable device (1) comprises a polymer structure (40) having an outer surface facing a surrounding tissue when the implantable device (1) is implanted in a subject body. At least a portion of the surface of the structure (40) has a semi-random pattern of extending micropillars (50). The semi-random pattern of micropillars (50) on the surface contributes to advantageous surface characteristics of the implantable device (1) in terms of reducing adhesion viable cells to the implantable device (1) as compared to regular patterns of micropillars (50).
摘要翻译: 可植入装置(1)包括聚合物结构(40),当将可植入装置(1)植入到被检体时,其具有面向周围组织的外表面。 结构(40)的表面的至少一部分具有延伸微柱(50)的半随机图案。 就可将可植入装置(1)的可固定细胞减少到与微柱(50)的规则图案相比而言,表面上的微柱(50)的半随机图案有助于可植入装置(1)的有利的表面特性。
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公开(公告)号:US08874234B2
公开(公告)日:2014-10-28
申请号:US13980284
申请日:2011-11-08
CPC分类号: A61N1/05 , A61B5/00 , A61B5/042 , A61B2560/0406 , A61B2562/12 , A61F2/0077 , A61L27/18 , A61L27/50 , A61L2400/12 , A61L2400/18 , A61N1/056 , A61N1/375 , C08L75/04 , C08L83/04
摘要: An implantable device comprises a polymer structure having an outer surface facing a surrounding tissue when the implantable device is implanted in a subject body. At least a portion of the surface of the structure has a semi-random pattern of extending micropillars. The semi-random pattern of micropillars on the surface contributes to advantageous surface characteristics of the implantable device in terms of reducing adhesion viable cells to the implantable device as compared to regular patterns of micropillars.
摘要翻译: 可植入装置包括聚合物结构,当将可植入装置植入被检体时,其具有面向周围组织的外表面。 结构的表面的至少一部分具有延伸微孔的半随机图案。 与常规的微柱模式相比,在表面上的微柱的半随机图案有助于可植入装置的有利的表面特性,以减少与可植入装置的粘附活细胞。
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