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公开(公告)号：US08394321B2
公开(公告)日：2013-03-12
申请号：US12992540
申请日：2009-04-27
申请人： Giuseppe Franzoni , Luca Caleffi , Ranko Sakota
发明人： Giuseppe Franzoni , Luca Caleffi , Ranko Sakota
CPC分类号： A61M5/16845 , A61M1/342 , A61M5/1689 , A61M2205/3386 , A61M2205/3393
摘要： In an infusion circuit (1), a peristaltic pump (7) displaced the infusion fluid along a line (3), sourcing it from a batch container (2). When a weight sensor (5) detects an emptying of the batch container (2), the pump is halted. If on stopping the pump the pressure measured by a sensor (6) operating in an expansion chamber (4) does not drop in excess of a predetermined threshold with respect to a non-empty container (2), a non-secure situation is signalled, due to an excessive quantity of air in the expansion chamber.
摘要翻译： 在输注电路（1）中，蠕动泵（7）沿着线（3）使输液流体从批料容器（2）中提取出来。 当重量传感器（5）检测到批量容器（2）的排空时，泵停止。 如果在停止泵时，在膨胀室（4）中操作的传感器（6）测量的压力相对于非空容器（2）不会下降超过预定阈值，则发出不安全的情况 ，由于膨胀室中的空气过多。
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公开(公告)号：US08728020B2
公开(公告)日：2014-05-20
申请号：US12681487
申请日：2007-10-04
申请人： Luca Caleffi , Ranko Sakota , Giuseppe Franzoni
发明人： Luca Caleffi , Ranko Sakota , Giuseppe Franzoni
IPC分类号： A61M37/00
CPC分类号： A61M5/1684 , A61M1/342 , A61M1/3434 , A61M1/3437 , A61M5/14232 , A61M5/16845 , A61M5/16854 , A61M5/36 , A61M2005/1402 , A61M2205/15
摘要： In an infusion apparatus, an infusion line (4) connects a container (2) of an infusion fluid to an extracorporeal blood circuit (23). A first valve (6) closes the infusion line downstream of an infusion pump (5). An expansion chamber (9), provided with a pressure sensor (10), is arranged between the infusion pump and the first valve. A second valve (8) closes a vent line (7) of the expansion chamber. The processor closes the first valve when the container is emptied. After replacement with a new and full container, the processor restarts the pump and selectively opens the first valve or the second valve according to the increase in pressure measured in the expansion chamber.
摘要翻译： 在输液装置中，输注管线（4）将输液的容器（2）连接到体外血液回路（23）。 第一阀（6）关闭输液泵（5）下游的输液管线。 设置有压力传感器（10）的膨胀室（9）设置在输液泵和第一阀之间。 第二阀（8）关闭膨胀室的排气管线（7）。 当容器倒空时，处理器关闭第一个阀门。 在更换新的和完整的容器后，处理器重新启动泵，并根据在膨胀室中测量的压力的增加选择性地打开第一阀或第二阀。
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公开(公告)号：US20100329926A1
公开(公告)日：2010-12-30
申请号：US12918414
申请日：2008-02-19
申请人： Giuseppe Franzoni , Luca Caleffi , Ranko Sakota
发明人： Giuseppe Franzoni , Luca Caleffi , Ranko Sakota
CPC分类号： A61M1/342 , A61M1/3434 , A61M1/3437 , A61M1/3621 , A61M1/3627 , A61M2205/123 , B01D19/0036
摘要： An extracorporeal blood circuit defines a blood course comprising a first conduit (27) having an upturned U shape forming a curve with a convex external side facing upwards. The circuit has an infusion fluid course with a terminal tract (28) opening into the extracorporeal blood course at said convex external side. The first conduit and the terminal tract are integrated in a single rigid body (20). The circuit enables an optimal mixture between the blood flow and the infusion fluid flow in a relatively-small mixing space.
摘要翻译： 体外血液回路限定血液流路，其包括具有向上翻转的U形的第一导管（27），其形成具有朝向上方的凸形外侧的曲线。 电路具有输液流程，其中在所述外凸侧的外侧血液通道中开有终端管道（28）。 第一管道和终端管道集成在单个刚体（20）中。 该电路使得在相对较小的混合空间中的血流和输注液之间的最佳混合。
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公开(公告)号：US20100288761A1
公开(公告)日：2010-11-18
申请号：US12447647
申请日：2006-10-30
IPC分类号： B65D47/02
CPC分类号： A61M1/3627 , A61M1/3434 , A61M1/3437 , A61M1/3465
摘要： An extracorporeal blood chamber (12) comprises an expansion reservoir (47) having a first access (48) arranged laterally and a second access (49) arranged on the bottom of the chamber (12). The chamber comprises, integrally with the reservoir, a first conduit terminating in the first access, a second conduit terminating in the first access, and a third conduit terminating in the second access. The extracorporeal blood enters the reservoir through the first conduit and there mixes with an infusion fluid which enters through the second conduit. The resulting mixture exits through the third conduit. The chamber is used in a hemo(dia)filtration apparatus to mix the blood optimally with the replacement fluid.
摘要翻译： 体外血液室（12）包括具有横向布置的第一通路（48）和布置在腔室（12）的底部上的第二通路（49））的膨胀容器（47）。 所述腔室与所述贮存器一体地包括终止于所述第一通道中的第一管道，终止于所述第一通路中的第二管道，以及终止于所述第二通路中的第三管道。 体外血液通过第一导管进入储存器，并且与通过第二导管进入的输注液混合。 所得混合物通过第三导管排出。 该腔室用于血液（dia）过滤装置以最佳地将血液与替换液体混合。
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公开(公告)号：US20100256547A1
公开(公告)日：2010-10-07
申请号：US12517020
申请日：2006-12-01
IPC分类号： A61M5/00
CPC分类号： A61M1/3627 , A61M1/0056
摘要： In a blood transfer chamber, a filter (4) is arranged at an outlet located on a bottom of the chamber. The filter is truncoconical with a vertically-disposed axis. The filter has a plurality of openings (13, 14) for fluid passage, a size of which openings increases gradually in an upwards direction going from bottom to top of the chamber. The filter is used in a venous air-blood separation chamber of a dialysis set. The invention enables a reduction of a risk of hemolysis during treatment as well as a reduction of the risk of formation of air bubble retention in the filter during a priming stage.
摘要翻译： 在血液输送室中，过滤器（4）布置在位于腔室底部的出口处。 过滤器具有垂直设置的轴的截面。 过滤器具有用于流体通道的多个开口（13,14），其开口的尺寸在从底部到顶部的向上方向上逐渐增加。 该过滤器用于透析装置的静脉空气 - 血液分离室。 本发明能够降低治疗期间溶血的风险，并且降低在起泡阶段期间在过滤器中形成气泡保留的风险。
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公开(公告)号：US08641657B2
公开(公告)日：2014-02-04
申请号：US12517020
申请日：2006-12-01
CPC分类号： A61M1/3627 , A61M1/0056
摘要： In a blood transfer chamber, a filter (4) is arranged at an outlet located on a bottom of the chamber. The filter is truncoconical with a vertically-disposed axis. The filter has a plurality of openings (13, 14) for fluid passage, a size of which openings increases gradually in an upwards direction going from bottom to top of the chamber. The filter is used in a venous air-blood separation chamber of a dialysis set. The invention enables a reduction of a risk of hemolysis during treatment as well as a reduction of the risk of formation of air bubble retention in the filter during a priming stage.
摘要翻译： 在血液输送室中，过滤器（4）布置在位于腔室底部的出口处。 过滤器具有垂直设置的轴的截面。 过滤器具有用于流体通道的多个开口（13,14），其开口的尺寸在从底部到顶部的向上方向上逐渐增加。 该过滤器用于透析装置的静脉空气 - 血液分离室。 本发明能够降低治疗期间溶血的风险，并且降低在起泡阶段期间在过滤器中形成气泡保留的风险。
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公开(公告)号：US08500672B2
公开(公告)日：2013-08-06
申请号：US12745454
申请日：2007-12-04
申请人： Luca Caleffi , Giuseppe Franzoni , Francesco Ribolzi , Ranko Sakota , Antonio Rega , Aldo Calimeri , Davide Marchesi
发明人： Luca Caleffi , Giuseppe Franzoni , Francesco Ribolzi , Ranko Sakota , Antonio Rega , Aldo Calimeri , Davide Marchesi
IPC分类号： A61M37/00
CPC分类号： A61M1/3627 , A61M5/165
摘要： An extracorporeal blood circuit, comprising an expansion chamber for air-blood separation, wherein a filter (38) retains the solid particles in the blood. The filter has a trunco-conical filtering wall with a vertical axis surmounted by a top head (43) provided with upper openings (44) conformed and arranged such as to define a fluid passage which is asymmetrical with respect to the vertical axis. The top head does not retain air bubbles internally thereof, thus preventing a situation in which the air bubbles are directed towards an outlet of the expansion chamber and thus towards the patient. The extracorporeal circuit is used in a dialysis apparatus.
摘要翻译： 一种体外血液回路，包括用于空气 - 血液分离的膨胀室，其中过滤器（38）将固体颗粒保持在血液中。 过滤器具有中空锥形过滤壁，其垂直轴线由顶部设置有顶部开口（43），上部开口（44）构成并布置成限定相对于垂直轴线不对称的流体通道。 顶部的头部内部不保留气泡，从而防止气泡朝向膨胀室的出口并因而导向患者的情况。 体外循环用于透析设备。
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公开(公告)号：USD644730S1
公开(公告)日：2011-09-06
申请号：US29318836
申请日：2008-05-29
申请人： Giuseppe Franzoni , Ranko Sakota , Luca Caleffi
设计人： Giuseppe Franzoni , Ranko Sakota , Luca Caleffi
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公开(公告)号：US20110064612A1
公开(公告)日：2011-03-17
申请号：US12992540
申请日：2009-04-27
申请人： Giuseppe Franzoni , Luca Caleffi , Ranko Sakota
发明人： Giuseppe Franzoni , Luca Caleffi , Ranko Sakota
IPC分类号： A61M1/34
CPC分类号： A61M5/16845 , A61M1/342 , A61M5/1689 , A61M2205/3386 , A61M2205/3393
摘要： In an infusion circuit (1), a peristaltic pump (7) displaced the infusion fluid along a line (3), sourcing it from a batch container (2). When a weight sensor (5) detects an emptying of the batch container (2), the pump is halted. If on stopping the pump the pressure measured by a sensor (6) operating in an expansion chamber (4) does not drop in excess of a predetermined threshold with respect to a non-empty container (2), a non-secure situation is signalled, due to an excessive quantity of air in the expansion chamber.
摘要翻译： 在输注电路（1）中，蠕动泵（7）沿着线（3）使输液流体从批料容器（2）中提取出来。 当重量传感器（5）检测到批量容器（2）的排空时，泵停止。 如果在停止泵时，在膨胀室（4）中操作的传感器（6）测量的压力相对于非空容器（2）不会下降超过预定阈值，则发出不安全的情况 ，由于膨胀室中的空气过多。
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公开(公告)号：US08647291B2
公开(公告)日：2014-02-11
申请号：US12447647
申请日：2006-10-30
IPC分类号： A61M37/00
CPC分类号： A61M1/3627 , A61M1/3434 , A61M1/3437 , A61M1/3465
摘要： An extracorporeal blood chamber (12) comprises an expansion reservoir (47) having a first access (48) arranged laterally and a second access (49) arranged on the bottom of the chamber (12). The chamber comprises, integrally with the reservoir, a first conduit terminating in the first access, a second conduit terminating in the first access, and a third conduit terminating in the second access. The extracorporeal blood enters the reservoir through the first conduit and there mixes with an infusion fluid which enters through the second conduit. The resulting mixture exits through the third conduit. The chamber is used in a hemo(dia)filtration apparatus to mix the blood optimally with the replacement fluid.
摘要翻译： 体外血液室（12）包括具有横向布置的第一通路（48）和布置在腔室（12）的底部上的第二通路（49））的膨胀容器（47）。 所述腔室与所述贮存器一体地包括终止于所述第一通道中的第一管道，终止于所述第一通路中的第二管道，以及终止于所述第二通路中的第三管道。 体外血液通过第一导管进入储存器，并且与通过第二导管进入的输注液混合。 所得混合物通过第三导管排出。 该腔室用于血液（dia）过滤装置以最佳地将血液与替换液体混合。
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