公开(公告)号：US20250010057A1

公开(公告)日：2025-01-09

申请号：US18888529

申请日：2024-09-18

Applicant: MAGENTA MEDICAL LTD

Inventor： Ori Friedland ,  Yuval Zipory ,  Yuri Sudin ,  Ayelet Haimy ,  Ehud Schwammenthal ,  Yosi Tuval ,  Tak Gee Cheung

IPC: A61M60/531 ,  A61B17/12 ,  A61M60/13 ,  A61M60/178 ,  A61M60/216 ,  A61M60/546 ,  A61M60/833 ,  A61M60/867

Abstract: Apparatus and methods are described for use with a venous system of a subject that includes one or more tributary vessels that flow into a vein at junctions. A blood-pump-catheter includes a material configured to be placed at a downstream location that is downstream of the junctions and to at least partially occlude blood flow through the vein. The material defines a blood-outlet opening. A blood pump pumps blood from a region of the vein that is adjacent to the junctions, and through the blood-outlet opening. A blood-flow pathway directs upstream venous blood flow from an upstream location that is upstream of the junctions, to downstream of the material, without the upstream venous blood flow being pumped by the pump. Other applications are also described.

公开(公告)号：US20220218976A1

公开(公告)日：2022-07-14

申请号：US17608312

申请日：2020-05-20

Applicant: MAGENTA MEDICAL LTD

Inventor： Ori Friedland ,  Yuval Zipory ,  Yuri Sudin ,  Ayelet Haimy ,  Ehud Schwammenthal ,  Yosi Tuval ,  Tak Gee Cheung

IPC: A61M60/13 ,  A61M60/216 ,  A61B17/12 ,  A61M60/857 ,  A61M60/531 ,  A61M60/546

Abstract: Apparatus and methods are described for use with a venous system of a subject that includes one or more tributary vessels that flow into a vein at junctions. A blood-pump-catheter (70) includes a material (36) configured to be placed at a downstream location that is downstream of the junctions and to at least partially occlude blood flow through the vein. The material defines a blood-outlet opening (31). A blood pump (24) pumps blood from a region of the vein that is adjacent to the junctions, and through the blood-outlet opening (31). A blood-flow pathway (60) directs upstream venous blood flow from an upstream location that is upstream of the junctions, to downstream of the material (36), without the upstream venous blood flow being pumped by the pump (24). Other applications are also described.

公开(公告)号：US20220184376A1

公开(公告)日：2022-06-16

申请号：US17682104

申请日：2022-02-28

Applicant: MAGENTA MEDICAL LTD.

Inventor： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC: A61M60/857 ,  A61M60/13 ,  A61M60/174 ,  A61M60/237 ,  A61M60/419 ,  A61M60/538 ,  A61M60/808 ,  A61M60/816 ,  A61M60/818 ,  A61M60/829

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes an impeller configured to be placed inside a subject's left ventricle and to pump blood from the left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the aorta and a distal portion of the tube is disposed within the left ventricle. The distal portion of the tube extends to the distal end of the frame and defines more than 10 blood-inlet openings that are sized such as (a) to allow blood to flow from the subject's left ventricle into the tube and (b) to block structures from the subject's left ventricle from entering into the frame. Other applications are also described.

公开(公告)号：US20220079457A1

公开(公告)日：2022-03-17

申请号：US17532318

申请日：2021-11-22

Applicant: MAGENTA MEDICAL LTD.

Inventor： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC: A61B5/0215 ,  A61M60/226 ,  A61M60/178 ,  A61M60/419 ,  A61M60/531 ,  A61B5/021

Abstract: Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject. A driving magnet is coupled to a motor and is rotated by the motor. A driven magnet is magnetically coupled to the driving magnet and is rotated by the driving magnet. A drive cable extends from the driven magnet and imparts rotational motion from the driven magnet to the impeller. A set of sensors is configured to detect a magnetic phase difference between the driven magnet and the driving magnet. A computer processor receives the detected magnetic phase difference and determines a physiological parameter of the subject, at least partially in response thereto. Other applications are also described.

公开(公告)号：US12128228B2

公开(公告)日：2024-10-29

申请号：US17608312

申请日：2020-05-20

Applicant: MAGENTA MEDICAL LTD

Inventor： Ori Friedland ,  Yuval Zipory ,  Yuri Sudin ,  Ayelet Haimy ,  Ehud Schwammenthal ,  Yosi Tuval ,  Tak Gee Cheung

IPC: A61M60/13 ,  A61B17/12 ,  A61M60/178 ,  A61M60/216 ,  A61M60/531 ,  A61M60/546 ,  A61M60/833 ,  A61M60/857 ,  A61M60/867

CPC classification number: A61M60/531 ,  A61B17/12181 ,  A61M60/13 ,  A61M60/178 ,  A61M60/216 ,  A61M60/546 ,  A61M60/833 ,  A61M60/867

Abstract: Apparatus and methods are described for use with a venous system of a subject that includes one or more tributary vessels that flow into a vein at junctions. A blood-pump-catheter (70) includes a material (36) configured to be placed at a downstream location that is downstream of the junctions and to at least partially occlude blood flow through the vein. The material defines a blood-outlet opening (31). A blood pump (24) pumps blood from a region of the vein that is adjacent to the junctions, and through the blood-outlet opening (31). A blood-flow pathway (60) directs upstream venous blood flow from an upstream location that is upstream of the junctions, to downstream of the material (36), without the upstream venous blood flow being pumped by the pump (24). Other applications are also described.

公开(公告)号：US12128227B2

公开(公告)日：2024-10-29

申请号：US17528807

申请日：2021-11-17

Applicant: MAGENTA MEDICAL LTD.

Inventor： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC: A61M60/237 ,  A61B5/021 ,  A61B5/0215 ,  A61M60/13 ,  A61M60/135 ,  A61M60/174 ,  A61M60/178 ,  A61M60/216 ,  A61M60/226 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/523 ,  A61M60/531 ,  A61M60/538 ,  A61M60/546 ,  A61M60/808 ,  A61M60/816 ,  A61M60/818 ,  A61M60/825 ,  A61M60/857 ,  A61M60/865 ,  A61M60/804 ,  A61M60/829

CPC classification number: A61M60/237 ,  A61B5/02141 ,  A61B5/0215 ,  A61M60/13 ,  A61M60/135 ,  A61M60/174 ,  A61M60/178 ,  A61M60/216 ,  A61M60/226 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/523 ,  A61M60/531 ,  A61M60/538 ,  A61M60/546 ,  A61M60/808 ,  A61M60/816 ,  A61M60/818 ,  A61M60/825 ,  A61M60/857 ,  A61M60/865 ,  A61B2562/0223 ,  A61M60/804 ,  A61M60/829 ,  A61M2205/3327 ,  A61M2207/00

Abstract: Apparatus and methods are described including manufacturing an impeller by forming a structure having first and second bushings at proximal and distal ends of the structure, the first and second bushings being connected to one another by at least one elongate element. The elongate element is caused to radially expand and form at least one helical elongate element, at least partially by axially compressing the structure. The helical elongate element is coated with a coupling agent configured to enhance bonding between the helical elongate element and an elastomeric layer. The coated helical elongate element is coated with the elastomeric layer. Subsequently, an elastomeric film is coupled to the helical elongate element, such that the helical elongate element with the elastomeric film coupled thereto defines a blade of the impeller. Other applications are also described.

公开(公告)号：US20220226632A1

公开(公告)日：2022-07-21

申请号：US17609589

申请日：2021-04-06

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC: A61M60/135 ,  A61B5/021 ,  A61B5/0215 ,  A61M60/13 ,  A61M60/178 ,  A61M60/226 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/523 ,  A61M60/531 ,  A61M60/538 ,  A61M60/808 ,  A61M60/816 ,  A61M60/825 ,  A61M60/857 ,  A61M60/865

Abstract: Apparatus and methods are described including an impeller (50) that includes a proximal bushing (64) and a distal bushing (58). Two or more helical elongate elements (52) extend from the proximal bushing (64) to the distal bushing (58), and an axial structure (54) is disposed inside of the two or more helical elongate elements (52), and along an axis around which the helical elongate elements (52) wind. The impeller (50) includes an impeller-overexpansion-prevention element (72). The impeller-overexpansion-prevention element is a single integrated structure that includes a ring (73) disposed around the axial structure (54), and a plurality of elongate elements (67) each of the elongate elements (67) extending from the ring to a respective helical elongate element (52) and being coupled to the respective helical elongate element (52) so as to prevent radial expansion of the impeller (50). Other applications are also described.

公开(公告)号：US20220072297A1

公开(公告)日：2022-03-10

申请号：US17528807

申请日：2021-11-17

Applicant: MAGENTA MEDICAL LTD.

Inventor： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC: A61M60/237 ,  A61M60/825 ,  A61M60/808 ,  A61M60/13 ,  A61M60/865

Abstract: Apparatus and methods are described including manufacturing an impeller by forming a structure having first and second bushings at proximal and distal ends of the structure, the first and second bushings being connected to one another by at least one elongate element. The elongate element is caused to radially expand and form at least one helical elongate element, at least partially by axially compressing the structure. The helical elongate element is coated with a coupling agent configured to enhance bonding between the helical elongate element and an elastomeric layer. The coated helical elongate element is coated with the elastomeric layer. Subsequently, an elastomeric film is coupled to the helical elongate element, such that the helical elongate element with the elastomeric film coupled thereto defines a blade of the impeller. Other applications are also described.

公开(公告)号：US20250073447A1

公开(公告)日：2025-03-06

申请号：US18949258

申请日：2024-11-15

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi Tuval ,  Yinnon Elisha ,  David Israeli ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yuval Zipory ,  Avi Rozenfeld ,  Aurelie Benaddi ,  Gilad Moiseyev ,  Yuri Sudin

IPC: A61M60/237 ,  A61B5/021 ,  A61B5/0215 ,  A61M60/13 ,  A61M60/135 ,  A61M60/174 ,  A61M60/178 ,  A61M60/216 ,  A61M60/226 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/523 ,  A61M60/531 ,  A61M60/538 ,  A61M60/546 ,  A61M60/804 ,  A61M60/808 ,  A61M60/816 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/857 ,  A61M60/865

Abstract: Apparatus and methods are described including a blood pump that includes an impeller, and a frame disposed around the impeller. An axial shaft extends from a proximal end of the frame to a distal end of the frame. The impeller is coupled to the axial shaft. A radial bearing is configured to radially stabilize the axial shaft and aa bearing housing houses the radial bearing. A layer of elastomeric material is disposed between the radial bearing and the bearing housing. Other applications are also described.

公开(公告)号：US20230137473A1

公开(公告)日：2023-05-04

申请号：US17907618

申请日：2021-03-29

Applicant: MAGENTA MEDICAL LTD

Inventor： Yuval Zipory ,  Ori Friedland ,  Yonatan Levi ,  Yosi Tuval

IPC: A61M60/13 ,  A61M60/232 ,  A61M60/812

Abstract: Apparatus and methods are described including a left-ventricular assist device (20) that includes a pump-outlet tube (28). A mixed-flow impeller (100) is configured to pump blood from a subjects left ventricle to the subjects aorta, by pumping the blood into the pump-outlet tube (28) via one or more blood inlet openings (108) disposed within the left ventricle, and by pumping blood out of the pump-outlet tube (28) via one or more blood outlet openings (30) disposed within the aorta. The mixed-flow impeller (100) includes an expandable portion (116) disposed along its axis and shaped such that a diameter of the expandable portion increases from a distal end of the expandable portion to its proximal end. The mixed-flow impeller (100) is configured to impart radial flow components to blood as the blood flows from its distal end to its proximal end. Other applications are also described.