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公开(公告)号:US20240285932A1
公开(公告)日:2024-08-29
申请号:US18652962
申请日:2024-05-02
申请人: Magenta Medical Ltd
发明人: Yosi Tuval , Gad Lubinsky , Victor Troshin , Hagit Zemer Harel , Ori Friedland , Daniel Rosenblum , Avi Rozenfeld
IPC分类号: A61M60/808 , A61M60/13 , A61M60/174 , A61M60/237 , A61M60/414 , A61M60/81 , A61M60/825
CPC分类号: A61M60/808 , A61M60/13 , A61M60/174 , A61M60/237 , A61M60/414 , A61M60/81 , A61M60/825
摘要: Apparatus and methods are described including a ventricular assist device that includes an axial shaft and an impeller disposed on the axial shaft, the impeller being configured to pump blood. A frame is disposed around the impeller. The distal end of the axial shaft is configured to engage with a distal thrust bearing such as to prevent the axial shaft from undergoing axial motion in response to variations in the pressure gradient against which the impeller pumps blood. An impeller-stabilizing spring is disposed around the axial shaft between a distal end of the impeller and the thrust bearing, the impeller-stabilizing spring being configured to stabilize the distal end of the impeller. Other applications are also described.
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公开(公告)号:US20220218976A1
公开(公告)日:2022-07-14
申请号:US17608312
申请日:2020-05-20
申请人: MAGENTA MEDICAL LTD
发明人: Ori Friedland , Yuval Zipory , Yuri Sudin , Ayelet Haimy , Ehud Schwammenthal , Yosi Tuval , Tak Gee Cheung
IPC分类号: A61M60/13 , A61M60/216 , A61B17/12 , A61M60/857 , A61M60/531 , A61M60/546
摘要: Apparatus and methods are described for use with a venous system of a subject that includes one or more tributary vessels that flow into a vein at junctions. A blood-pump-catheter (70) includes a material (36) configured to be placed at a downstream location that is downstream of the junctions and to at least partially occlude blood flow through the vein. The material defines a blood-outlet opening (31). A blood pump (24) pumps blood from a region of the vein that is adjacent to the junctions, and through the blood-outlet opening (31). A blood-flow pathway (60) directs upstream venous blood flow from an upstream location that is upstream of the junctions, to downstream of the material (36), without the upstream venous blood flow being pumped by the pump (24). Other applications are also described.
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公开(公告)号:US20230211147A1
公开(公告)日:2023-07-06
申请号:US18122504
申请日:2023-03-16
申请人: MAGENTA MEDICAL LTD
发明人: Yosi Tuval , Gad Lubinsky , Hagit Zemer Harel , Ori Friedland , Daniel Rosenblum , Avi Rozenfeld
IPC分类号: A61M60/855 , A61M60/216 , A61M60/174 , A61M60/81 , A61M60/414 , A61M60/508 , A61M60/806
CPC分类号: A61M60/855 , A61M60/216 , A61M60/174 , A61M60/81 , A61M60/414 , A61M60/508 , A61M60/806
摘要: Apparatus and methods are described including a ventricular assist device that includes an impeller disposed within a frame and configured to pump blood through a pump-outlet tube and out of one of more blood outlet openings. The frame includes an inner lining. A protective braid is disposed over a distal portion of the frame and configured to block structures from the subject's left ventricle from entering into the frame. A proximal end of the protective braid is embedded between the pump-outlet tube and the inner lining, such that, during crimping of the frame, the braid becomes crimped with the pump-outlet tube and the inner lining, thereby preventing the braid from moving with respect to pump-outlet tube or the inner lining. Other applications are also described.
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公开(公告)号:US20230137473A1
公开(公告)日:2023-05-04
申请号:US17907618
申请日:2021-03-29
申请人: MAGENTA MEDICAL LTD
发明人: Yuval Zipory , Ori Friedland , Yonatan Levi , Yosi Tuval
IPC分类号: A61M60/13 , A61M60/232 , A61M60/812
摘要: Apparatus and methods are described including a left-ventricular assist device (20) that includes a pump-outlet tube (28). A mixed-flow impeller (100) is configured to pump blood from a subjects left ventricle to the subjects aorta, by pumping the blood into the pump-outlet tube (28) via one or more blood inlet openings (108) disposed within the left ventricle, and by pumping blood out of the pump-outlet tube (28) via one or more blood outlet openings (30) disposed within the aorta. The mixed-flow impeller (100) includes an expandable portion (116) disposed along its axis and shaped such that a diameter of the expandable portion increases from a distal end of the expandable portion to its proximal end. The mixed-flow impeller (100) is configured to impart radial flow components to blood as the blood flows from its distal end to its proximal end. Other applications are also described.
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公开(公告)号:US12128228B2
公开(公告)日:2024-10-29
申请号:US17608312
申请日:2020-05-20
申请人: MAGENTA MEDICAL LTD
发明人: Ori Friedland , Yuval Zipory , Yuri Sudin , Ayelet Haimy , Ehud Schwammenthal , Yosi Tuval , Tak Gee Cheung
IPC分类号: A61M60/13 , A61B17/12 , A61M60/178 , A61M60/216 , A61M60/531 , A61M60/546 , A61M60/833 , A61M60/857 , A61M60/867
CPC分类号: A61M60/531 , A61B17/12181 , A61M60/13 , A61M60/178 , A61M60/216 , A61M60/546 , A61M60/833 , A61M60/867
摘要: Apparatus and methods are described for use with a venous system of a subject that includes one or more tributary vessels that flow into a vein at junctions. A blood-pump-catheter (70) includes a material (36) configured to be placed at a downstream location that is downstream of the junctions and to at least partially occlude blood flow through the vein. The material defines a blood-outlet opening (31). A blood pump (24) pumps blood from a region of the vein that is adjacent to the junctions, and through the blood-outlet opening (31). A blood-flow pathway (60) directs upstream venous blood flow from an upstream location that is upstream of the junctions, to downstream of the material (36), without the upstream venous blood flow being pumped by the pump (24). Other applications are also described.
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公开(公告)号:US20240277997A1
公开(公告)日:2024-08-22
申请号:US18652959
申请日:2024-05-02
申请人: Magenta Medical Ltd
发明人: Yosi Tuval , Gad Lubinsky , Victor Troshin , Hagit Zemer Harel , Ori Friedland , Daniel Rosenblum , Avi Rozenfeld
IPC分类号: A61M60/808 , A61M60/13 , A61M60/174 , A61M60/237 , A61M60/414 , A61M60/81 , A61M60/825
CPC分类号: A61M60/808 , A61M60/13 , A61M60/174 , A61M60/237 , A61M60/414 , A61M60/81 , A61M60/825
摘要: Apparatus and methods are described including a pump-outlet tube configured to traverse an aortic valve of a subject, such that the proximal end of the pump-outlet tube is disposed within the subject's aorta and the distal end of the pump-outlet tube is disposed within the subject's left ventricle. An impeller is configured to be disposed within the left ventricle within the pump-outlet tube, and to pump blood through the pump-outlet tube. A frame, disposed around the impeller, includes a cylindrical portion and a proximal conical portion. A proximal end of an optical fiber is disposed outside the subject's body and the distal end of the optical fiber is coupled to the proximal conical portion of the frame such that the distal end of the optical fiber extends to outside the pump-outlet tube in direct fluid communication with left-ventricular bloodstream of the subject. Other applications are also described.
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公开(公告)号:US20240245903A1
公开(公告)日:2024-07-25
申请号:US18447025
申请日:2022-08-30
申请人: Magenta Medical Ltd
发明人: Yosi Tuval , Gad Lubinsky , Victor Troshin , Hagit Zemer Harel , Ori Friedland , Daniel Rosenblum , Avi Rozenfeld
IPC分类号: A61M60/808 , A61M60/13 , A61M60/174 , A61M60/237 , A61M60/414 , A61M60/81 , A61M60/825
CPC分类号: A61M60/808 , A61M60/13 , A61M60/174 , A61M60/237 , A61M60/414 , A61M60/81 , A61M60/825
摘要: Apparatus and methods are described including a ventricular assist device. An impeller is placed inside a left ventricle of a subject, the impeller defining a lumen therethrough. A frame is disposed around the impeller, with a proximal bearing disposed at a proximal end of the frame and a distal bearing disposed at a distal end of the frame. An axial shaft passes through the proximal bearing, the lumen defined by the impeller, and the distal bearing. A motion-cushioning spring is disposed around the axial shaft between a distal end of the impeller and the distal bearing, the motion-cushioning spring being configured to cushion axial motion that the impeller undergoes. Other applications are also described.
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公开(公告)号:US20230233836A1
公开(公告)日:2023-07-27
申请号:US18122456
申请日:2023-03-16
申请人: MAGENTA MEDICAL LTD
发明人: Yosi Tuval , Gad Lubinsky , Hagit Zemer Harel , Ori Friedland , Daniel Rosenblum , Avi Rozenfeld
IPC分类号: A61M60/237 , A61M60/148
CPC分类号: A61M60/237 , A61M60/148 , A61M60/205
摘要: Apparatus and methods are described for manufacturing a housing for an impeller of a blood pump. A frame is treated in order to enhance bonding between an inner surface of the frame and an inner lining. Subsequently, the inner lining is coupled to the inner surface of the frame along at least a portion of a central cylindrical portion of the frame. Subsequent to coupling the inner lining to the inner surface of the frame along at least a portion of the central cylindrical portion of the frame, a portion of an elongate tube is placed around at least a portion of the frame. While heating the inner lining, the frame, and the portion of the elongate tube, pressure is applied such as to cause the portion of the elongate tube to become coupled to the frame. Other applications are also described.
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公开(公告)号:US20230226342A1
公开(公告)日:2023-07-20
申请号:US18001680
申请日:2022-03-07
申请人: MAGENTA MEDICAL LTD
发明人: Yosi Tuval , Gad Lubinsky , Hagit Zemer Harel , Ori Friedland , Daniel Rosenblum , Avi Rozenfeld
IPC分类号: A61M60/178 , A61M60/237 , A61M60/411 , A61M60/818 , A61M60/508 , A61M60/808 , A61M60/865
CPC分类号: A61M60/178 , A61M60/237 , A61M60/411 , A61M60/818 , A61M60/508 , A61M60/808 , A61M60/865 , A61M2207/10
摘要: Apparatus and methods are described including a left-ventricular assist device that includes an impeller (50) and a frame (34) disposed around the impeller (50). The frame (34) includes strut junctions (33) at a proximal end of the frame, the strut junctions (33) being configured to be maintained in open states, during assembly of the left ventricular assist device, to facilitate insertion of the impeller (50) into the frame (34). A securing element (117) holds the struts junctions in closed states, subsequent to the insertion of the impeller (50) into the frame (34). A pump-outlet tube (24) extends to a distal end of the frame (34) and defines one or more lateral blood inlet openings (108) that are configured to allow blood to flow from the subject's left ventricle into the pump-outlet tube (24). Other applications are also described.
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公开(公告)号:US20230218884A1
公开(公告)日:2023-07-13
申请号:US18121995
申请日:2023-03-15
申请人: MAGENTA MEDICAL LTD
发明人: Yosi Tuval , Gad Lubinsky , Hagit Zemer Harel , Ori Friedland , Daniel Rosenblum , Avi Rozenfeld
IPC分类号: A61M60/148 , A61M60/247
CPC分类号: A61M60/148 , A61M60/247
摘要: Apparatus and methods are described including a left-ventricular assist device including an impeller and a frame disposed around the impeller. A pump-outlet tube traverses the subject's aortic valve with a distal portion of the pump-outlet tube disposed within the subject's left ventricle. The distal portion of the pump-outlet tube extends to a distal end of the frame and defines more than 10 blood-inlet openings that are sized such as (a) to allow blood to flow from the subject's left ventricle into the tube and (b) to block structures from the subject's left ventricle from entering into the frame. The porosity of the distal portion of the pump-outlet tube is lower within a proximal region of the distal portion of the pump-outlet tube than within a distal region of the distal portion of the pump-outlet tube that is distal to the proximal region. Other applications are also described.
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