公开(公告)号：US20120270305A1

公开(公告)日：2012-10-25

申请号：US13273666

申请日：2011-10-14

申请人： MARK T. REED ,  ERIC WILLIAMSON ,  BRYAN CRANE ,  PATRICK LEUNG ,  DALE BUERMANN ,  ALEXANDER P. KINDWALL ,  Frederick ERIE ,  MARK PRATT ,  JASON HARRIS ,  ANDREW JAMES CARSON ,  Stanley S. HONG ,  JASON BRYANT ,  MARK WANG ,  DREW VERKADE

发明人： MARK T. REED ,  ERIC WILLIAMSON ,  BRYAN CRANE ,  PATRICK LEUNG ,  DALE BUERMANN ,  ALEXANDER P. KINDWALL ,  Frederick ERIE ,  MARK PRATT ,  JASON HARRIS ,  ANDREW JAMES CARSON ,  Stanley S. HONG ,  JASON BRYANT ,  MARK WANG ,  DREW VERKADE

IPC分类号： C12M1/34 ,  G01N1/00 ,  G01N21/00 ,  B01L9/00

CPC分类号： B01L3/502715 ,  B01L7/52 ,  B01L9/527 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/04 ,  B01L2200/0689 ,  B01L2300/022 ,  B01L2300/041 ,  B01L2300/043 ,  B01L2300/0816 ,  B01L2300/0877 ,  G01N21/05 ,  G01N2021/058 ,  Y10T436/25

摘要： A fluidic device holder configured to orient a fluidic device. The device holder includes a support structure configured to receive a fluidic device. The support structure includes a base surface that faces in a direction along the Z-axis and is configured to have the fluidic device positioned thereon. The device holder also includes a plurality of reference surfaces facing in respective directions along an XY-plane. The device holder also includes an alignment assembly having an actuator and a movable locator arm that is operatively coupled to the actuator. The locator arm has an engagement end. The actuator moves the locator arm between retracted and biased positions to move the engagement end away from and toward the reference surfaces. The locator arm is configured to hold the fluidic device against the reference surfaces when the locator arm is in the biased position.

摘要翻译： 流体装置保持器，其构造成定向流体装置。 装置保持器包括构造成接收流体装置的支撑结构。 所述支撑结构包括在Z轴方向上面对并且被配置成具有定位在其上的流体装置的基面。 装置保持器还包括沿着XY平面在各个方向上面对的多个参考表面。 装置保持器还包括具有致动器和可操作地联接到致动器的可动定位臂的对准组件。 定位臂具有接合端。 致动器将定位臂移动到缩回位置和偏置位置之间，以使接合端远离参考表面移动。 定位臂构造成当定位臂处于偏置位置时将流体装置保持在参考表面上。

公开(公告)号：US20110188053A1

公开(公告)日：2011-08-04

申请号：US12947367

申请日：2010-11-16

申请人： DALE BUERMANN ,  ALEXANDER P. KINDWALL

发明人： DALE BUERMANN ,  ALEXANDER P. KINDWALL

IPC分类号： G01B11/24 ,  G01B11/14

CPC分类号： G02B21/247 ,  G02B21/245

摘要： A method for controlling a focus of an optical system. The method includes providing a pair of incident light beams to a conjugate lens. The incident light beams are directed by the lens to converge toward a focal region. The method also includes reflecting the incident light beams with an object positioned proximate to the focal region. The reflected light beams return to and propagate through the lens. The method also includes determining relative separation measured between the reflected light beams and determining a degree-of-focus of the optical system with respect to the sample based upon the relative separation.

摘要翻译： 一种用于控制光学系统的焦点的方法。 该方法包括将一对入射光束提供给共轭透镜。 入射光束被透镜引导以朝向焦点区域会聚。 该方法还包括用邻近聚焦区域定位的物体反射入射光束。 反射光束返回并传播通过透镜。 该方法还包括确定在反射光束之间测量的相对间隔，并基于相对间隔确定光学系统相对于样品的焦度。