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公开(公告)号：US20230145008A1
公开(公告)日：2023-05-11
申请号：US18049405
申请日：2022-10-25
Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventor： Hugh M. Herr , Benjamin Maimon , Anthony Zorzos
CPC classification number: A61N1/327 , A61K9/0009 , A61K9/0019 , A61N1/0412 , A61N5/062 , A61N5/0622 , C07K14/47 , C12N15/86 , A61N2005/0651 , A61N2005/0659 , A61N2005/0661 , A61N2005/0663 , C12N2750/14143 , C12N2830/008 , A61N5/067
Abstract: A nerve in a mammal is optogenetically transduced, wherein the nerve is susceptible to stimulus by selective application of transdermal light, and a light source is applied to dermis of the mammal at or proximate to the optogenetically transduced nerve, to thereby stimulate the nerve. A wearable device for optogenetic motor control and sensation restoration of a mammal includes a wearable support, a power source at the wearable support, a controller at the wearable support and in electrical communication with a power source, and a transdermal light source coupled to the controller.
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Patent Agency Ranking
2.发明申请公开(公告)号：US20220031479A1
公开(公告)日：2022-02-03
申请号：US17451584
申请日：2021-10-20
Applicant: Massachusetts Institute of Technology
Inventor： Hugh M. Herr , Tyler Clites , Benjamin Maimon , Anthony Zorzos , Matthew J. Carty , Jean-Francois Duval , Shriya Sruthi Srinivasan
Abstract: Proprioceptive feedback is provided in a residual limb of a person that includes forming a linkage between a pair of agonist and antagonist muscles, forming a sliding surface over which the agonist and antagonist muscles slide. The sliding surface can include a synovial sleeve, a bridge formed between the distal ends of bones, or a fixture that is osseointegrated into the bone. The invention also includes a system for transdermal electrical communication in a person that includes a percutaneous access device, a sensory device that communicates signals between a muscle and the percutaneous device, and a stimulation device in communication with the percutaneous access device. In another embodiment, a closed-loop functional stimulation system restores lost functionality to a person that suffers from impairment of a neurological control system or at least partial loss of a limb.
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3.发明申请公开(公告)号：US20190021883A1
公开(公告)日：2019-01-24
申请号：US16068531
申请日：2017-01-06
Applicant: Massachusetts Institute of Technology
Inventor： Hugh M. Herr , Tyler Clites , Benjamin Maimon , Anthony Zorzos , Matthew J. Carty , Jean-Francois Duval
Abstract: Proprioceptive feedback is provided in a residual limb of a person that includes forming a linkage between a pair of agonist and antagonist muscles, forming a sliding surface over which the agonist and antagonist muscles slide. The sliding surface can include a synovial sleeve, a bridge formed between the distal ends of bones, or a fixture that is osseointegrated into the bone. The invention also includes a system for transdermal electrical communication in a person that includes a percutaneous access device, a sensory device that communicates signals between a muscle and the percutaneous device, and a stimulation device in communication with the percutaneous access device. In another embodiment, a closed-loop functional stimulation system restores lost functionality to a person that suffers from impairment of a neurological control system or at least partial loss of a limb.
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公开(公告)号：US11504530B2
公开(公告)日：2022-11-22
申请号：US16344866
申请日：2017-10-31
Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventor： Hugh M. Herr , Benjamin Maimon , Anthony Zorzos
Abstract: A nerve in a mammal is optogenetically transduced, wherein the nerve is susceptible to stimulus by selective application of transdermal light, and a light source is applied to dermis of the mammal at or proximate to the optogenetically transduced nerve, to thereby stimulate the nerve. A wearable device for optogenetic motor control and sensation restoration of a mammal includes a wearable support, a power source at the wearable support, a controller at the wearable support and in electrical communication with a power source, and a transdermal light source coupled to the controller.
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5.发明授权公开(公告)号：US11179251B2
公开(公告)日：2021-11-23
申请号：US16068531
申请日：2017-01-06
Applicant: Massachusetts Institute of Technology
Inventor： Hugh M. Herr , Tyler Clites , Benjamin Maimon , Anthony Zorzos , Matthew J. Carty , Jean-Francois Duval , Shriya Sruthi Srinivasan
IPC: A61F2/72 , A61N1/36 , A61F2/64 , A61F2/80 , A61H3/00 , A61N5/06 , A61F2/78 , A61N1/05 , A61F2/50 , A61F2/68 , A61F2/70
Abstract: Proprioceptive feedback is provided in a residual limb of a person that includes forming a linkage between a pair of agonist and antagonist muscles, forming a sliding surface over which the agonist and antagonist muscles slide. The sliding surface can include a synovial sleeve, a bridge formed between the distal ends of bones, or a fixture that is osseointegrated into the bone. The invention also includes a system for transdermal electrical communication in a person that includes a percutaneous access device, a sensory device that communicates signals between a muscle and the percutaneous device, and a stimulation device in communication with the percutaneous access device. In another embodiment, a closed-loop functional stimulation system restores lost functionality to a person that suffers from impairment of a neurological control system or at least partial loss of a limb.
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公开(公告)号：US20200046968A1
公开(公告)日：2020-02-13
申请号：US16344866
申请日：2017-10-31
Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventor： Hugh M. Herr , Benjamin Maimon , Anthony Zorzos
Abstract: A nerve in a mammal is optogenetically transduced, wherein the nerve is susceptible to stimulus by selective application of transdermal light, and a light source is applied to dermis of the mammal at or proximate to the optogenetically transduced nerve, to thereby stimulate the nerve. A wearable device for optogenetic motor control and sensation restoration of a mammal includes a wearable support, a power source at the wearable support, a controller at the wearable support and in electrical communication with a power source, and a transdermal light source coupled to the controller.
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