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    Microneedle arrays and methods for fabricating microneedle arrays
    1.
    发明授权
    Microneedle arrays and methods for fabricating microneedle arrays 有权

    公开(公告)号：US10525244B2

    公开(公告)日：2020-01-07

    申请号：US15719353

    申请日：2017-09-28

    Applicant: MEDTRONIC MINIMED, INC.

    Inventor： James A. Reitz ,  Raymond M. Russell ,  Anthony C. Cannistraci ,  David Pavell

    IPC: A61M37/00 ,  B21D22/02 ,  A61B5/00 ,  A61B5/145

    Abstract: Microneedle arrays, methods for fabricating microneedle arrays, medical devices, and methods for operating medical devices are provided. A method for fabricating a microneedle array includes providing a sheet blank of material. Further, the method includes stamping the sheet blank of material with a progression of dies, wherein the material is displaced into the microneedle array. A medical device includes a microneedle array, a base member having a first surface supporting the microneedle array and a second surface, and a flexible wall enclosing a chamber between the flexible wall and the second surface of the base member. The flexible wall is biased toward an extended configuration enclosing a first volume in the chamber. Further, the flexible wall is movable to a depressed configuration enclosing a second volume in the chamber less than the first volume.

    Medical devices with microneedle arrays and methods for operating such medical devices
    4.
    发明授权
    Medical devices with microneedle arrays and methods for operating such medical devices 有权

    公开(公告)号：US10524730B2

    公开(公告)日：2020-01-07

    申请号：US15719359

    申请日：2017-09-28

    Applicant: MEDTRONIC MINIMED, INC.

    Inventor： James A. Reitz ,  Raymond M. Russell ,  Anthony C. Cannistraci ,  David Pavell

    IPC: A61B5/00 ,  A61B5/145 ,  A61M37/00 ,  B21D22/28

    Abstract: Microneedle arrays, methods for fabricating microneedle arrays, medical devices, and methods for operating medical devices are provided. A method for fabricating a microneedle array includes providing a sheet blank of material. Further, the method includes stamping the sheet blank of material with a progression of dies, wherein the material is displaced into the microneedle array. A medical device includes a microneedle array, a base member having a first surface supporting the microneedle array and a second surface, and a flexible wall enclosing a chamber between the flexible wall and the second surface of the base member. The flexible wall is biased toward an extended configuration enclosing a first volume in the chamber. Further, the flexible wall is movable to a depressed configuration enclosing a second volume in the chamber less than the first volume.

    SYSTEMS AND METHODS FOR ASSESSING SENSOR SURFACE AREA ENCAPSULATION IN VITRO AND IN VIVO
    5.
    发明公开
    SYSTEMS AND METHODS FOR ASSESSING SENSOR SURFACE AREA ENCAPSULATION IN VITRO AND IN VIVO 审中-公开

    公开(公告)号：US20240341635A1

    公开(公告)日：2024-10-17

    申请号：US18603875

    申请日：2024-03-13

    Applicant: Medtronic MiniMed, Inc.

    Inventor： Raymond M. Russell ,  Steven Jacks

    IPC: A61B5/145

    CPC classification number: A61B5/14532 ,  A61B2560/0228 ,  A61B2560/0238

    Abstract: A glucose sensor includes a working electrode, sensor electronics configured to periodically measure electrode current signal (Isig) values for the working electrode and counter voltage values (Vcntr) for the glucose sensor, one or more processors, and one or more processor-readable media. The one or more processor-readable media stores instructions which, when executed by the one or more processors, cause performance of: generating Electrochemical Impedance Spectroscopy (EIS) parameter values for the working electrode based on an EIS procedure; estimating a reaction surface area of the glucose sensor based on least one of Isig values, Vcntr values, or the EIS parameter values; determining a difference between the estimated reaction surface area and an expected reaction surface area of the glucose sensor; comparing the determined difference to a predetermined threshold value; and adjusting a calibration factor when the determined difference is below the predetermined threshold value.

    MINIATURIZED NONINVASIVE GLUCOSE SENSOR AND CONTINUOUS GLUCOSE MONITORING SYSTEM
    7.
    发明申请
    MINIATURIZED NONINVASIVE GLUCOSE SENSOR AND CONTINUOUS GLUCOSE MONITORING SYSTEM 有权

    公开(公告)号：US20220257154A1

    公开(公告)日：2022-08-18

    申请号：US17734245

    申请日：2022-05-02

    Applicant: Medtronic MiniMed, Inc.

    Inventor： Li Zhou ,  Raymond M. Russell ,  Peter Schultz

    IPC: A61B5/145 ,  A61B5/00

    Abstract: The disclosed techniques involve a light emitter configured to emit light toward the skin of a person, a light emitter controller configured to control the light emitter to emit the light in pulses having a pulse duration and at a pulse repetition frequency, a resonance chamber positioned to receive acoustic waves generated in the person in response to the light emitted by the light emitter, a sensor configured to sense acoustic waves in the resonance chamber, and a signal processor configured to estimate a glucose concentration level in the person based on the acoustic waves sensed by the sensor. The resonance chamber is sized to form a standing wave that has an acoustic wavelength of interest when glucose analytes are present in the region of the skin of the person. The pulse duration and the pulse repetition frequency of the emitted light are set at values that support the standing wave having the acoustic wavelength of interest.

    MEDICAL DEVICES WITH MICRONEEDLE ARRAYS AND METHODS FOR OPERATING SUCH MEDICAL DEVICES
    8.
    发明申请
    MEDICAL DEVICES WITH MICRONEEDLE ARRAYS AND METHODS FOR OPERATING SUCH MEDICAL DEVICES 审中-公开

    公开(公告)号：US20190090811A1

    公开(公告)日：2019-03-28

    申请号：US15719359

    申请日：2017-09-28

    Applicant: MEDTRONIC MINIMED, INC.

    Inventor： James A. Reitz ,  Raymond M. Russell ,  Anthony C. Cannistraci ,  David Pavell

    IPC: A61B5/00 ,  A61B5/145 ,  A61M37/00

    Abstract: Microneedle arrays, methods for fabricating microneedle arrays, medical devices, and methods for operating medical devices are provided. A method for fabricating a microneedle array includes providing a sheet blank of material. Further, the method includes stamping the sheet blank of material with a progression of dies, wherein the material is displaced into the microneedle array. A medical device includes a microneedle array, a base member having a first surface supporting the microneedle array and a second surface, and a flexible wall enclosing a chamber between the flexible wall and the second surface of the base member. The flexible wall is biased toward an extended configuration enclosing a first volume in the chamber. Further, the flexible wall is movable to a depressed configuration enclosing a second volume in the chamber less than the first volume.

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