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    MUTING GLUCOSE SENSOR OXYGEN RESPONSE AND REDUCING ELECTRODE EDGE GROWTH WITH PULSED CURRENT PLATING
    4.
    发明申请
    MUTING GLUCOSE SENSOR OXYGEN RESPONSE AND REDUCING ELECTRODE EDGE GROWTH WITH PULSED CURRENT PLATING 审中-公开
    静脉注射葡萄糖传感器氧气反应并减少电极边缘生长与脉冲电流

    公开(公告)号：US20140243634A1

    公开(公告)日：2014-08-28

    申请号：US13779584

    申请日：2013-02-27

    申请人： MEDTRONIC MINIMED, INC.

    发明人： Ting Huang ,  Ashwin K. Rao ,  Rajiv Shah ,  Qingling Yang

    IPC分类号： A61B5/145 ,  A61B5/1477

    CPC分类号： A61B5/14532 ,  A61B5/1477

    摘要： The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.

    摘要翻译： 本文公开的本发明包括电流葡萄糖传感器，其具有由以下方式形成的电极：电沉积铂黑以产生相对平滑的三维金属结构的方式，这些结构有助于传感器的可靠性和稳定性。 本发明的实施例提供具有这种均匀电极结构的分析物传感器以及用于制造和使用这些传感器电极的方法。 本发明的多个实施方案被证明可用于由糖尿病患者佩戴的电流葡萄糖传感器。

    Medicine injection devices, systems, and methods for medicine administration and tracking
    6.
    发明授权
    Medicine injection devices, systems, and methods for medicine administration and tracking 有权

    公开(公告)号：US11904146B2

    公开(公告)日：2024-02-20

    申请号：US17342449

    申请日：2021-06-08

    申请人： Medtronic MiniMed, Inc.

    发明人： Ellis Garai ,  Ashwin K. Rao

    IPC分类号： A61M5/315

    CPC分类号： A61M5/31568 ,  A61M2205/18 ,  A61M2205/3306 ,  A61M2205/52

    摘要： A medicine delivery and tracking system includes a medicine injection pen and a delivery port. The pen includes a needle through which medicine is dispensed and an electronic unit configured to at least one of log dispensing of medicine from the pen, control dispensing of medicine from the pen, or communicate regarding dispensing of medicine from the pen. Alternatively, the electronic unit may be part of a separate computing device. The delivery port is configured for attachment to a user and to receive the needle of the pen such that medicine dispensed from the pen is dispensed into the delivery port and through the delivery port to the user. The delivery port includes a detector mechanism configured to detect a presence of the pen and, in response thereto, to communicate a signal to the electronic unit for use in the at least one of logging, controlling, or communicating.

    IN-SITU CHEMISTRY STACK FOR CONTINUOUS GLUCOSE SENSORS
    10.
    发明申请
    IN-SITU CHEMISTRY STACK FOR CONTINUOUS GLUCOSE SENSORS 审中-公开

    公开(公告)号：US20170315077A1

    公开(公告)日：2017-11-02

    申请号：US15141446

    申请日：2016-04-28

    申请人： Medtronic MiniMed, Inc.

    发明人： Ashwin K. Rao ,  Daniel E. Pesantez

    IPC分类号： G01N27/327 ,  G01N27/30 ,  C12Q1/00

    CPC分类号： G01N27/3272 ,  A61B5/14532 ,  A61B5/14865 ,  A61B2562/125 ,  C12Q1/002 ,  C12Q1/003 ,  C12Q1/006 ,  G01N27/307

    摘要： Embodiments of the invention provide an in-situ polymerization technique for creating a glucose sensor chemistry stack. An analyte sensor comprises a crosslinked polymer matrix in contact with an electrode. The crosslinked polymer matrix is formed by exposing ultraviolet (UV) light to a polymer matrix mixture comprising a plurality of hydroxyethyl methacrylate (HEMA) monomers, one or more di-acrylate crosslinkers, one or more UV photoinitiators, and an oxidoreductase. The oxidoreductase is covalently linked to the crosslinked polymer matrix. In typical embodiments, the oxidoreductase is a glucose oxidase-acrylate bioconjugate. In one or more embodiments, the analyte sensor apparatus further comprises a glucose limiting membrane positioned over the crosslinked polymer matrix. The glucose limiting membrane is formed by exposing ultraviolet (UV) light to a glucose limiting membrane mixture comprising a plurality of hydroxyethyl methacrylate (HEMA) monomers, one or more di-acrylate crosslinkers, one or more UV photoinitiators, ethylene glycol, and water.