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公开(公告)号：US20220381780A1
公开(公告)日：2022-12-01
申请号：US17749721
申请日：2022-05-20
申请人： Meso Scale Technologies, LLC. , The United States of America,as represented by the Secretary,Department of Health and Human Services
发明人： Jacob N. WOHLSTADTER , George SIGAL , James WILBUR , Jeffery DEBAD , Hans BIEBUYCK , Priscilla KRAI , Alan KISHBAUGH , Leonid DZANTIEV , Christopher SHELBURNE , Christopher CAMPBELL , Anastasia AKSYUK , Adrian MCDERMOTT , Sarah O'CONNELL , Sandeep NARPALA , Chien Li LIN
IPC分类号： G01N33/569 , G01N33/543 , G01N33/58
摘要： The invention relates to methods and kits for determining a SARS-CoV-2 strain in a sample. The invention further provides methods and kits for detecting a single nucleotide polymorphism (SNP) in a target nucleic acid, wherein the target nucleic acid is a SARS-CoV-2 nucleic acid. The invention further provides methods and kits for detecting one or more antibody biomarkers in a sample.
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公开(公告)号：US20230184768A1
公开(公告)日：2023-06-15
申请号：US17997267
申请日：2021-04-30
发明人： Jacob N. WOHLSTADTER , George SIGAL , Anu MATHEW , James WILBUR , Jeffery DEBAD , Christopher CAMPBELL , Hans BIEBUYCK , Priscilla KRAI , Alan KISHBAUGH , Leonid DZANTIEV , Christopher SHELBURNE , Pu LIU , Paul GOODWIN
IPC分类号： G01N33/569 , G01N33/68
CPC分类号： G01N33/56983 , G01N33/6854 , G01N2333/11 , G01N2333/165 , G01N2469/20
摘要： The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.
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公开(公告)号：US20220341843A1
公开(公告)日：2022-10-27
申请号：US17733036
申请日：2022-04-29
发明人： Nicholas ANDERSON , Jeffery DEBAD , Eli N. GLEZER , Sudeep KUMAR , Noel LAWRENCE , Kenneth PAGE , George SIGAL , Sharon WEST
IPC分类号： G01N21/05 , G01N21/69 , G01N21/76 , B01L3/00 , G01N21/03 , G01F23/02 , G01F23/292 , G01N1/10
摘要： Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, thy reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge.
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公开(公告)号：US20210349104A1
公开(公告)日：2021-11-11
申请号：US17246364
申请日：2021-04-30
申请人： Meso Scale Technologies, LLC. , The United States of America,as represented by the Secretary,Department of Health and Human Services
发明人： Jacob N. WOHLSTADTER , George SIGAL , Anu MATHEW , James WILBUR , Jeffery DEBAD , Christopher CAMPBELL , Hans BIEBUYCK , Priscilla KRAI , Alan KISHBAUGH , Leonid DZANTIEV , Christopher SHELBURNE , Pu LIU , Paul GOODWIN , Adrian MCDERMOTT , Sarah O'CONNELL , Sandeep NARPALA
IPC分类号： G01N33/68
摘要： The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.
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