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公开(公告)号：US20210349104A1
公开(公告)日：2021-11-11
申请号：US17246364
申请日：2021-04-30
申请人： Meso Scale Technologies, LLC. , The United States of America,as represented by the Secretary,Department of Health and Human Services
发明人： Jacob N. WOHLSTADTER , George SIGAL , Anu MATHEW , James WILBUR , Jeffery DEBAD , Christopher CAMPBELL , Hans BIEBUYCK , Priscilla KRAI , Alan KISHBAUGH , Leonid DZANTIEV , Christopher SHELBURNE , Pu LIU , Paul GOODWIN , Adrian MCDERMOTT , Sarah O'CONNELL , Sandeep NARPALA
IPC分类号： G01N33/68
摘要： The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.
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公开(公告)号：US20220381780A1
公开(公告)日：2022-12-01
申请号：US17749721
申请日：2022-05-20
申请人： Meso Scale Technologies, LLC. , The United States of America,as represented by the Secretary,Department of Health and Human Services
发明人： Jacob N. WOHLSTADTER , George SIGAL , James WILBUR , Jeffery DEBAD , Hans BIEBUYCK , Priscilla KRAI , Alan KISHBAUGH , Leonid DZANTIEV , Christopher SHELBURNE , Christopher CAMPBELL , Anastasia AKSYUK , Adrian MCDERMOTT , Sarah O'CONNELL , Sandeep NARPALA , Chien Li LIN
IPC分类号： G01N33/569 , G01N33/543 , G01N33/58
摘要： The invention relates to methods and kits for determining a SARS-CoV-2 strain in a sample. The invention further provides methods and kits for detecting a single nucleotide polymorphism (SNP) in a target nucleic acid, wherein the target nucleic acid is a SARS-CoV-2 nucleic acid. The invention further provides methods and kits for detecting one or more antibody biomarkers in a sample.
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公开(公告)号：US20240018571A1
公开(公告)日：2024-01-18
申请号：US17999076
申请日：2021-05-18
发明人： John KENTEN , Jacob N. WOHLSTADTER
IPC分类号： C12Q1/6818
CPC分类号： C12Q1/6818
摘要： The invention relates to methods, oligonucleotide reagents, compositions, and kits for nucleic acid detection.
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公开(公告)号：US20220365106A1
公开(公告)日：2022-11-17
申请号：US17679663
申请日：2022-02-24
发明人： Manish KOCHAR , Peter J. BOSCO , Ian D. CHAMBERLIN , Bandele JEFFREY-COKER , Eric M. JONES , Gary I. KRIVOY , Don E. KRUEGER , Aaron H. LEIMKUEHLER , Pei-Ming WU , Kim-Xuan NGUYEN , Pankaj OBEROI , Louis W. PANG , Jennifer PARKER , Victor PELLICIER , Nicholas SAMMONS , George SIGAL , Jacob N. WOHLSTADTER , Michael L. VOCK , Stanley T. SMITH , Carl C. STEVENS , Rodger D. OSBORNE , Kenneth E. PAGE , Michael T. WADE , Jon WILLOUGHBY , Lei WANG
IPC分类号： G01N35/00 , B01L3/00 , B01L9/00 , G16H40/67 , G16H10/40 , G16H40/40 , F24F11/30 , G06K7/14 , G06Q10/08 , G06Q10/10
摘要： The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.
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公开(公告)号：US20210407692A1
公开(公告)日：2021-12-30
申请号：US17359479
申请日：2021-06-25
摘要： Provided herein are systems, methods, and apparatuses for providing a real-time global bio-surveillance and response solution. The systems and apparatuses may include one or more sentinel subsystems and one or more surge subsystems that each include a real-time, cloud-based, distributed, interconnected set of hardware, software, and/or firmware for comprehensive surveillance, complete detection, and immediate response various to biological, chemical, and/or bio-chemical anomalies, for example, a new or emerging pathogen or other health condition.
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公开(公告)号：US20210389338A1
公开(公告)日：2021-12-16
申请号：US17412688
申请日：2021-08-26
发明人： Manish KOCHAR , Peter J. BOSCO , Ian D. CHAMBERLIN , Bandele JEFFREY-COKER , Eric M. JONES , Gary I. KRIVOY , Aaron H. LEIMKUEHLER , Pei-Ming WU , Kim-Xuan NGUYEN , Pankaj OBEROI , Louis W. PANG , Jennifer PARKER , Victor PELLICIER , Nicholas SAMMONS , George SIGAL , Jacob N. WOHLSTADTER , Michael L. VOCK , Stanley T. SMITH , Carl C. STEVENS , Rodger D. OSBORNE , Kenneth E. PAGE , Michael T. WADE , Jon WILLOUGHBY , Lei WANG , Don E. KRUEGER
IPC分类号： G01N35/00 , B01L3/00 , B01L9/00 , G16H40/67 , G16H10/40 , G16H40/40 , F24F11/30 , G06K7/14 , G06Q10/08 , G06Q10/10
摘要： The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.
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公开(公告)号：US20220003766A1
公开(公告)日：2022-01-06
申请号：US17246360
申请日：2021-04-30
发明人： Jacob N. WOHLSTADTER , George SIGAL , Anu MATHEW , Anastasia AKSYUK , David ROUTENBERG , Martin STENGELIN , John KENTEN , Timothy J. BREAK , Seth B. HARKINS , Michael TSIONSKY
IPC分类号： G01N33/569 , C12Q1/70
摘要： The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.
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公开(公告)号：US20240287572A1
公开(公告)日：2024-08-29
申请号：US18555331
申请日：2022-04-15
摘要： The invention relates to methods, compositions, and kits for detection of hydrolase enzyme activity in a sample.
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公开(公告)号：US20240272116A1
公开(公告)日：2024-08-15
申请号：US18441769
申请日：2024-02-14
发明人： Manish KOCHAR , Mark BILLADEAU , Charles M. CLINTON , Scott DOWDELL , Aaron H. LEIMKUEHLER , Alexander K. TUCKER-SCHWARTZ , Jules VANDERSARL , Jon WILLOUGHBY , Jacob N. WOHLSTADTER
IPC分类号： G01N27/417 , G01N27/30 , G01N27/327
CPC分类号： G01N27/417 , G01N27/301 , G01N27/305 , G01N27/308 , G01N27/3277
摘要： Electrochemical cells and methods for their production are provided. In particular, multi-well assay plates including multi-electrode wells are provided. The multi-electrode wells contain multiple electrodes that are electrically isolated from one another, permitting the various electrodes of the various wells to be addressed in any suitable combination.
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公开(公告)号：US20240264085A1
公开(公告)日：2024-08-08
申请号：US18617770
申请日：2024-03-27
IPC分类号： G01N21/76 , B01L3/00 , G01N21/64 , G01N33/543
CPC分类号： G01N21/76 , B01L3/502 , G01N21/6452 , G01N33/54366 , B01L2200/025 , B01L2200/18 , B01L2300/021 , B01L2300/0609 , B01L2300/0654 , B01L2300/0663 , B01L2300/0829 , B01L2300/0867 , G01N2201/068 , G01N2201/12
摘要： We describe a detection module useful with an apparatus and/or system for conducting luminescence assays, and a kit, a system, an apparatus, and a method incorporating the detection module.
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