公开(公告)号：US20230295696A1

公开(公告)日：2023-09-21

申请号：US18006375

申请日：2020-07-29

Applicant: MGI Tech Co., Ltd.

Inventor： Jay Shafto ,  Radoje Drmanac ,  Snezana Drmanac ,  Chongjun Xu ,  Meihua Gong ,  Ping Wang ,  Xiaojuan Long ,  Wei Zhao ,  Huan Luo ,  Hui Jiang ,  Jian Liu

IPC: C12Q1/6834 ,  C12Q1/686 ,  C40B50/18

CPC classification number: C12Q1/6834 ,  C12Q1/686 ,  C40B50/18 ,  C12Q2600/16

Abstract: Provided are a method for loading a nucleic acid molecule, for example nucleic acid nanoball (e.g., DNA nanoball (DNB)), on a solid support, and a kit for the method.

公开(公告)号：US12121902B2

公开(公告)日：2024-10-22

申请号：US17413039

申请日：2018-12-13

Applicant: MGI Tech Co., Ltd.

Inventor： Xing-Ye Cui ,  Zi-Hua Niu ,  Chu-Tian Xing ,  Jian Liu

IPC: B01L9/00 ,  G01N35/10

CPC classification number: B01L9/52 ,  G01N35/10 ,  B01L2200/025 ,  B01L2300/0819

Abstract: A portable sample loading device (1,4,7) include a base (11,41,71) and a fixing device (11,41,71) connected to the base (12,42,72). The base (12,42,72) can support a chip (2,5) and a sample loading connector (3,6). The fixing device (12,42,72) can detachably retain the chip (2,5) and the sample loading connector (3,6) on the base (11,41,71). The base (11,41,71) includes a front surface (110,410,710) and a back surface (111,411,711) opposite to the front surface (110,410,710). The front surface (110,410,710) includes a supporting surface for supporting the chip (2,5). A region of the supporting surface (112,412,712) corresponds to a sample inlet of the chip (2,5) is recessed toward the back surface (111,411,711) to form a receiving space (114,117,414,714) for receiving the sample loading connector (3,6). The receiving space (114,117,414,714) further defines a sample injection hole (115, 415,715) corresponding to the sample inlet of the chip (2,5).

公开(公告)号：US12117396B2

公开(公告)日：2024-10-15

申请号：US17763295

申请日：2019-09-24

Applicant: MGI Tech Co., Ltd.

Inventor： Heming Jiang ,  Chutian Xing ,  Joon Mo Yang ,  Xiangkun Sui ,  Jian Liu ,  Razvan Chirita ,  Zhonghai Wang ,  Simon Robert Adams ,  Le Wang ,  Mark Frederick Senko ,  Craig Edward Uhrich ,  Sicheng Wen ,  Pin Kao ,  Feng Mu

IPC: G01N21/63 ,  G01N21/03 ,  G01N21/13 ,  G01N21/85

CPC classification number: G01N21/63 ,  G01N21/0332 ,  G01N21/13 ,  G01N21/85

Abstract: A biochemical substance analysis system (5) is used to detect biological characteristics of a sample in a flow cell (38), and includes a detection system (51), a scheduling system (53), a biochemical reaction system (55), and a control system (57). The scheduling system (53) is used to schedule the flow cell (38) at different sites, including sites in the detection system (51) and sites in the biochemical reaction system (55). The biochemical reaction system (55) is used to allow the sample to react in the flow cell (38). The detection system (51) is used to detect a signal from the reacted sample to obtain a signal representing the biological characteristics of the sample. The control system (57) is used to control the detection system (51), the scheduling system (53), and the biochemical reaction system (55) to cooperate. The disclosure improves automation degree and flux of the biochemical substance analysis.

公开(公告)号：US20240376537A1

公开(公告)日：2024-11-14

申请号：US18689293

申请日：2021-09-07

Applicant: MGI Tech Co., Ltd.

Inventor： Meihua Gong ,  Mingxuan Zhang ,  Shuang Zhou ,  Xiaojuan Long ,  Chongjun Xu ,  Hui Jiang ,  Jian Liu

IPC: C12Q1/6869 ,  C12Q1/686 ,  C12Q1/6876

Abstract: The present invention relates to a method for analyzing a sequence of a target polynucleotide. Full polymerization is achieved by means of multiple times of polymerization of a nucleotide mixture and polymerase, and a marker is detected while the polymerization reaction is performed. Furthermore, the present invention relates to a kit, capable of being used for analyzing or sequencing a polynucleotide.