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公开(公告)号：US12071482B2
公开(公告)日：2024-08-27
申请号：US17407814
申请日：2021-08-20
发明人： Carlos J. Bosques , James S. Huston , Jonathan C. Lansing , Leona E. Ling , James Meador, III , Daniel Ortiz , Laura Rutitzky
CPC分类号： C07K16/283 , C07K14/00 , C07K16/00 , C07K16/46 , C07K2317/14 , C07K2317/33 , C07K2317/52 , C07K2317/526 , C07K2317/60 , C07K2319/30
摘要： The present invention relates to compositions and methods of engineered IgG Fc constructs, wherein said Fc constructs include one or more Fc domains.
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公开(公告)号：US20220267388A1
公开(公告)日：2022-08-25
申请号：US17527741
申请日：2021-11-16
摘要： The present disclosure relates to engineered IgG Fc constructs and uses thereof.
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公开(公告)号：US20220064298A1
公开(公告)日：2022-03-03
申请号：US17259271
申请日：2019-07-11
IPC分类号： C07K16/28
摘要： Fc-antigen binding constructs having a CTLA-4 binding domain and two or more Fc domains are described as are methods for using such constructs. Also described are polypeptides making up such constructs. Fc domain monomers that are included in the constructs can include amino acid substitutions that promote homodimerization or heterodimerization
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公开(公告)号：US20210238310A1
公开(公告)日：2021-08-05
申请号：US17259498
申请日：2019-07-11
发明人： Jonathan C. Lansing , Daniel Ortiz , Abhinav Gupta
IPC分类号： C07K16/42
摘要： The present disclosure relates to compositions and methods of engineered Fc-antigen binding domain constructs, where the Fc-antigen binding domain constructs include at least two Fc domains and at least one antigen binding domain.
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公开(公告)号：US20200040084A1
公开(公告)日：2020-02-06
申请号：US16474572
申请日：2018-01-05
IPC分类号： C07K16/28
摘要： The present disclosure relates to compositions and methods of engineered Fc-antigen binding domain constructs, where the Fc-antigen binding domain constructs include at least two Fc domains and at least one antigen binding domain.
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公开(公告)号：US20190225688A1
公开(公告)日：2019-07-25
申请号：US16363846
申请日：2019-03-25
发明人： Carlos J. Bosques , James S. Huston , Jonathan C. Lansing , Leona E. Ling , James Meador, III , Daniel Ortiz , Laura Rutitzky
摘要： The present invention relates to compositions and methods of engineered IgG Fc constructs, wherein said Fc constructs include one or more Fc domains.
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公开(公告)号：US20240279703A1
公开(公告)日：2024-08-22
申请号：US18218535
申请日：2023-07-05
发明人： Naveen Bhatnagar , Robin Meccariello , Jonathan C. Lansing , Daniel Ortiz , Hetal Sarvaiya , Nathaniel J. Washburn
CPC分类号： C12P21/005 , C07K16/00 , C12N9/1081 , C12Q1/48 , C12Y204/99001 , C12Y204/99003 , C07K2317/41 , C07K2317/52 , G01N2333/91091 , G01N2440/38
摘要： Glycoproteins having particular sialylation patterns, and methods of making and using such glycoproteins, are described.
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公开(公告)号：US20240209040A1
公开(公告)日：2024-06-27
申请号：US18520171
申请日：2023-11-27
CPC分类号： C07K14/47 , A61K39/0008 , A61P19/02 , A61P37/06 , A61K2039/577 , C07K2319/30
摘要： The present disclosure relates to engineered IgG Fc constructs and uses thereof.
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公开(公告)号：US20240067757A1
公开(公告)日：2024-02-29
申请号：US18298131
申请日：2023-04-10
IPC分类号： C07K16/46 , A61K39/395 , A61P37/06 , C07K16/00
CPC分类号： C07K16/46 , A61K39/395 , A61P37/06 , C07K16/00 , C07K16/468 , C07K2317/524 , C07K2317/526 , C07K2317/53 , C07K2317/60 , C07K2317/94 , C07K2319/30
摘要： The present disclosure relates to compositions and methods of engineered IgG Fc constructs, wherein the Fc constructs include one or more Fc domains.
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公开(公告)号：US11827682B2
公开(公告)日：2023-11-28
申请号：US17527741
申请日：2021-11-16
CPC分类号： C07K14/47 , A61K39/0008 , A61P19/02 , A61P37/06 , A61K2039/577 , C07K2319/30
摘要： The present disclosure relates to engineered IgG Fc constructs and uses thereof.
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