公开(公告)号：US11878165B2

公开(公告)日：2024-01-23

申请号：US17346971

申请日：2021-06-14

Applicant: MONASH UNIVERSITY

Inventor： Paul B Fitzgerald ,  Caley M. Sullivan ,  Richard H. Thomson

IPC: A61N1/36 ,  A61B5/00 ,  A61B5/369 ,  A61B5/375 ,  A61N1/04 ,  A61B5/389 ,  A61B1/05 ,  A61B5/318

CPC classification number: A61N1/36031 ,  A61B5/369 ,  A61B5/375 ,  A61B5/4064 ,  A61B5/4836 ,  A61B5/7203 ,  A61N1/36025 ,  A61B5/0042 ,  A61B5/318 ,  A61B5/389 ,  A61B5/6814 ,  A61N1/0476

Abstract: Closed-loop transcranial stimulation and monitoring is disclosed that includes generating a stimulation signal having a set of first oscillation parameters; applying the stimulation signal transcranially to a patient; monitoring the stimulation signal as applied to the patient; receiving a brain activity signal from the patient; generating a feedback signal based on the monitored stimulation signal as applied to the patient; and generating a modified activity signal by subtracting the feedback signal from the brain activity signal; determining one or more second oscillation parameters of the modified activity signal; and adjusting the set of first oscillation parameters of the stimulation signal based on the one or more second oscillation parameters of the modified activity signal. Closed-loop transcranial stimulation and monitoring is also disclosed in which the patient is engaged in a cognitive task.

公开(公告)号：US11065445B2

公开(公告)日：2021-07-20

申请号：US16092989

申请日：2017-04-10

Applicant: MONASH UNIVERSITY

Inventor： Paul B Fitzgerald ,  Caley M. Sullivan ,  Richard H. Thomson

IPC: A61N1/36 ,  A61B5/00 ,  A61B5/369 ,  A61B5/375 ,  A61N1/04 ,  A61B5/318 ,  A61B5/389

Abstract: Closed-loop transcranial stimulation and monitoring is disclosed that includes generating a stimulation signal having a set of first oscillation parameters; applying the stimulation signal transcranially to a patient; monitoring the stimulation signal as applied to the patient; receiving a brain activity signal from the patient; generating a feedback signal based on the monitored stimulation signal as applied to the patient; and generating a modified activity signal by subtracting the feedback signal from the brain activity signal; determining one or more second oscillation parameters of the modified activity signal; and adjusting the set of first oscillation parameters of the stimulation signal based on the one or more second oscillation parameters of the modified activity signal. Closed-loop transcranial stimulation and monitoring is also disclosed in which the patient is engaged in a cognitive task.