-
1.发明申请TUMOR MARKER AND METHOD FOR DETERMINATION OF THE OCCURRENCE OF CANCEROUS DISEASE 审中-公开肿瘤标志物和确定癌症发生的方法公开(公告)号：US20090191575A1
公开(公告)日：2009-07-30
申请号：US12303363
申请日：2007-06-05
申请人： Makoto Watanabe , Osamu Nishimura , Toshiya Matsubara , Ichiro Takemasa , Morito Monden , Katsuya Nagai , Nariaki Matsuura
发明人： Makoto Watanabe , Osamu Nishimura , Toshiya Matsubara , Ichiro Takemasa , Morito Monden , Katsuya Nagai , Nariaki Matsuura
IPC分类号： G01N33/574 , C12N9/12 , C12N9/24 , C07K14/00 , C12N9/10 , C12N9/14 , C12N9/50 , C12N9/02 , G01N33/573
CPC分类号： G01N33/57419
摘要： The present invention provides a tumor marker and a method capable of identifying the morbidity of colon cancer. A tumor marker including a protein identified from a colon cancer tissue. A method for identify the morbidity of colon cancer using the tumor marker. The method includes: measuring the level of the protein in a sample derived from a person of interest who should be examined to identify the morbidity of colon cancer; and comparing the measured level to the normal level of the protein, wherein a higher or lower measured level than the normal level is used as one indicator indicating that there is a high possibility that the person of interest has colon cancer.
摘要翻译： 本发明提供了能够鉴定结肠癌发病率的肿瘤标志物和方法。 包括从结肠癌组织鉴定的蛋白质的肿瘤标志物。 使用肿瘤标志物鉴定结肠癌发病率的方法。 该方法包括：测量衍生自感兴趣的人的样品中蛋白质的水平，其应当被检查以鉴定结肠癌的发病率; 并且将测量的水平与蛋白质的正常水平进行比较，其中使用比正常水平更高或更低的测量水平作为一个指标，指示感兴趣的人具有结肠癌的可能性很高。
-
2.发明申请Marker for judging lymph node metastasis of breast cancer, a primer, and a method for judging lymph node metastasis of breast cancer using the marker 审中-公开用于判断乳腺癌淋巴结转移的标记，引物，以及使用标记判断乳腺癌淋巴结转移的方法公开(公告)号：US20070259360A1
公开(公告)日：2007-11-08
申请号：US11730163
申请日：2007-03-29
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： The object of the present invention is to provide a novel marker for a correct diagnosis of lymph node metastasis of breast cancer. This object is attained by a marker for judging lymph node metastasis of tumor cells derived from breast cancer, the marker including mRNA of the gene encoding Forkhead box A1 (FOXA1) or a fragment thereof.
摘要翻译： 本发明的目的是提供用于乳腺癌淋巴结转移的正确诊断的新型标志物。 该目的通过用于判断来自乳腺癌的肿瘤细胞的淋巴结转移的标记物，包括编码Forkhead盒A1（FOXA1）的基因的mRNA或其片段的标记来实现。
-
3.发明申请IMAGE ANALYSIS APPARATUS, IMAGE ANALYSIS METHOD, IMAGE ANALYSIS PROGRAM AND RECORDING MEDIUM 有权图像分析设备，图像分析方法，图像分析程序和记录介质公开(公告)号：US20110274340A1
公开(公告)日：2011-11-10
申请号：US13145091
申请日：2010-01-13
IPC分类号： G06K9/00
CPC分类号： G06K9/00147 , G06T7/0012 , G06T7/12 , G06T7/187 , G06T7/62 , G06T2207/30024 , G06T2207/30096
摘要： A cancer determination apparatus (1) includes a Betti number calculation section (42) for calculating, in a captured image (i) in which a tissue is captured and (ii) which has been binarized by use of a prescribed reference value as a threshold, (I) the number of connected components and (II) the number of spaces, each of the connected components being an aggregate of at least one component which is defined by connecting an outer edge(s) of the at least one component which is a graphic having a closed outer edge, each of the spaces being surrounded by an outer edge(s) of the at least one component, a comparison value calculation section (43) for calculating a comparison value indicating a difference between the number of connected components and the number of spaces, and a determination section (44) for determining, by comparing the comparison value thus calculated with a predetermined reference value, whether or not an image of a cancer tissue is included in the captured image.
摘要翻译： 癌症确定装置（1）包括：贝蒂数计算部（42），用于计算在拍摄组织的拍摄图像（i）中和（ii）使用规定的基准值进行二值化的阈值作为阈值 ，（I）连接部件的数量和（II）空间数量，每个连接的部件是通过连接至少一个部件的外边缘而定义的至少一个部件的集合， 具有封闭的外边缘的图形，每个空间被所述至少一个部件的外边缘包围;比较值计算部分，用于计算指示连接部件数量之间的差异的比较值 以及确定部分（44），用于通过将由此计算的比较值与预定参考值进行比较，确定是否包括癌组织的图像。
-
4.发明授权Image analysis apparatus, image analysis method, image analysis program and recording medium 有权图像分析装置，图像分析方法，图像分析程序和记录介质公开(公告)号：US08718377B2
公开(公告)日：2014-05-06
申请号：US13145091
申请日：2010-01-13
CPC分类号： G06K9/00147 , G06T7/0012 , G06T7/12 , G06T7/187 , G06T7/62 , G06T2207/30024 , G06T2207/30096
摘要： A cancer determination apparatus (1) includes a Betti number calculation section (42) for calculating, in a captured image (i) in which a tissue is captured and (ii) which has been binarized by use of a prescribed reference value as a threshold, (I) the number of connected components and (II) the number of spaces, each of the connected components being an aggregate of at least one component which is defined by connecting an outer edge(s) of the at least one component which is a graphic having a closed outer edge, each of the spaces being surrounded by an outer edge(s) of the at least one component, a comparison value calculation section (43) for calculating a comparison value indicating a difference between the number of connected components and the number of spaces, and a determination section (44) for determining, by comparing the comparison value thus calculated with a predetermined reference value, whether or not an image of a cancer tissue is included in the captured image.
摘要翻译： 癌症确定装置（1）包括Betti数量计算部（42），用于在捕获组织的捕获图像（i）中计算（ii）使用规定的参考值进行二值化的阈值作为阈值 ，（I）连接部件的数量和（II）空间数量，每个连接的部件是通过连接至少一个部件的外边缘而定义的至少一个部件的集合， 具有封闭的外边缘的图形，每个空间被所述至少一个部件的外边缘包围;比较值计算部分，用于计算指示连接部件数量之间的差异的比较值 以及确定部分（44），用于通过将由此计算的比较值与预定参考值进行比较，确定是否包括癌组织的图像。
-
5.发明授权公开(公告)号：US08222216B2
公开(公告)日：2012-07-17
申请号：US12310577
申请日：2007-08-29
CPC分类号： A61L27/227 , A61L27/34 , A61L27/46 , A61L27/54 , A61L27/56 , A61L2300/25 , C07K7/06 , C12N5/0663 , C12N5/0664 , C12N2533/18 , C12N2533/50 , C12N2533/54 , C08L89/00
摘要： It is found that a SVVYGLR peptide (SEQ ID NO: 1) can promote proliferation of mesenchymal cells such as marrow-derived mesenchymal stem cells and dental pulp cells. A carbonate apatite-collagen sponge containing the SVVYGLR peptide (SEQ ID NO: 1) is useful as a biomaterial for the regeneration of bone marrow or dental pulp. It becomes possible to provide a skeletal system biomaterial which is capable of promoting the proliferation of the mesenchymal cells and is useful as artificial bone marrow or artificial dental pulp for repairing a defect in a bone marrow tissue or a dental pulp tissue.
摘要翻译： 发现SVVYGLR肽（SEQ ID NO：1）可以促进骨髓间充质干细胞和牙髓细胞等间充质细胞的增殖。 含有SVVYGLR肽（SEQ ID NO：1）的碳酸盐磷灰石胶原海绵可用作骨髓或牙髓的再生的生物材料。 可以提供骨骼系统生物材料，其能够促进间充质细胞的增殖，并且可用作修复骨髓组织或牙髓组织中的缺陷的人造骨髓或人造牙髓。
-
6.发明申请MESENCHYMAL CELL PROLIFERATION PROMOTER AND SKELETAL SYSTEM BIOMATERIAL 有权MESENCHYMAL细胞增殖促进剂和骨骼系统生物材料公开(公告)号：US20110245187A1
公开(公告)日：2011-10-06
申请号：US12310577
申请日：2007-08-29
CPC分类号： A61L27/227 , A61L27/34 , A61L27/46 , A61L27/54 , A61L27/56 , A61L2300/25 , C07K7/06 , C12N5/0663 , C12N5/0664 , C12N2533/18 , C12N2533/50 , C12N2533/54 , C08L89/00
摘要： It is found that a SVVYGLR peptide (SEQ ID NO: 1) can promote proliferation of mesenchymal cells such as marrow-derived mesenchymal stem cells and dental pulp cells. A carbonate apatite-collagen sponge containing the SVVYGLR peptide (SEQ ID NO: 1) is useful as a biomaterial for the regeneration of bone marrow or dental pulp. It becomes possible to provide a skeletal system biomaterial which is capable of promoting the proliferation of the mesenchymal cells and is useful as artificial bone marrow or artificial dental pulp for repairing a defect in a bone marrow tissue or a dental pulp tissue.
摘要翻译： 发现SVVYGLR肽（SEQ ID NO：1）可以促进骨髓间充质干细胞和牙髓细胞等间充质细胞的增殖。 含有SVVYGLR肽（SEQ ID NO：1）的碳酸盐磷灰石胶原海绵可用作骨髓或牙髓的再生的生物材料。 可以提供骨骼系统生物材料，其能够促进间充质细胞的增殖，并且可用作修复骨髓组织或牙髓组织中的缺陷的人造骨髓或人造牙髓。
-
公开(公告)号：US07091175B2
公开(公告)日：2006-08-15
申请号：US10491418
申请日：2002-10-02
IPC分类号： A01N37/18
CPC分类号： C07K7/06 , A61K38/08 , A61K47/6435 , A61L27/22 , A61L27/24 , A61L27/34 , C07K5/0806 , C07K5/081 , C07K5/1013 , C07K5/1016
摘要： A novel angiogenesis drug which can be clinically used for therapies of human or the like is disclosed. The angiogenesis drug according to the present invention comprises a peptide as an effective component, which has a prescribed amino acid sequence and has an angiogenesis action.
摘要翻译： 公开了可以临床上用于人类等的治疗的新型血管生成药物。 根据本发明的血管发生药物包含具有规定的氨基酸序列并具有血管生成作用的作为有效成分的肽。
-
-
-
-
-
-
搜索结果
7 条记录 (耗时 0.037 秒)
