公开(公告)号：US20240215615A1

公开(公告)日：2024-07-04

申请号：US18467362

申请日：2023-09-14

申请人： Manus Bio Inc.

发明人： Ryan PHILIPPE ,  Ajikumar Parayil KUMARAN ,  Jason DONALD ,  Krishna PATEL ,  Swati GUPTA ,  Ryan LIM ,  Liwei LI

IPC分类号： A23L2/60 ,  A23L27/30 ,  C12N9/02 ,  C12N9/10 ,  C12P19/56

CPC分类号： A23L2/60 ,  A23L27/36 ,  C12N9/0073 ,  C12N9/1048 ,  C12N9/1051 ,  C12P19/56 ,  C12Y114/13079 ,  C12Y204/01017 ,  A23V2002/00

摘要： The invention provides methods for making steviol glycosides, including RebM and glycosylation products that are minor products in stevia leaves, and provides enzymes, encoding polynucleotides, and host cells for use in these methods. The invention provides engineered enzymes and engineered host cells for producing steviol glycosylation products, such as RebM, at high purity and/or yield. The invention further provides methods of making products containing steviol glycosides, such as RebM, including food products, beverages, oral care products, sweeteners, and flavoring products.

公开(公告)号：US20190269157A1

公开(公告)日：2019-09-05

申请号：US16251993

申请日：2019-01-18

申请人： Manus Bio, Inc.

发明人： Ryan PHILIPPE ,  Ajikumar Parayil KUMARAN ,  Jason DONALD ,  Krishna PATEL ,  Swati GUPTA ,  Ryan LIM ,  Liwei LI

IPC分类号： A23L2/60 ,  C12N9/10 ,  C12N9/02 ,  C12P19/56 ,  A23L27/30

摘要： The invention provides methods for making steviol glycosides, including RebM and glycosylation products that are minor products in stevia leaves, and provides enzymes, encoding polynucleotides, and host cells for use in these methods. The invention provides engineered enzymes and engineered host cells for producing steviol glycosylation products, such as RebM, at high purity and/or yield. The invention further provides methods of making products containing steviol glycosides, such as RebM, including food products, beverages, oral care products, sweeteners, and flavoring products.

公开(公告)号：US20210022373A1

公开(公告)日：2021-01-28

申请号：US16862214

申请日：2020-04-29

申请人： Manus Bio, Inc.

发明人： Ryan PHILIPPE ,  Ajikumar Parayil KUMARAN ,  Jason DONALD ,  Krishna PATEL ,  Swati GUPTA ,  Ryan LIM ,  Liwei LI

IPC分类号： A23L2/60 ,  A23L27/30 ,  C12P19/56 ,  C12N9/10 ,  C12N9/02

摘要： The invention provides methods for making steviol glycosides, including RebM and glycosylation products that are minor products in stevia leaves, and provides enzymes, encoding polynucleotides, and host cells for use in these methods. The invention provides engineered enzymes and engineered host cells for producing steviol glycosylation products, such as RebM, at high purity and/or yield. The invention further provides methods of making products containing steviol glycosides, such as RebM, including food products, beverages, oral care products, sweeteners, and flavoring products.