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公开(公告)号：US09849247B2
公开(公告)日：2017-12-26
申请号：US13261383
申请日：2011-01-31
申请人： Margaret Taylor , James Bates , Roman Tunkel , Jay Butterbrodt , Gary Searle , Joshua Horvath , Keith Knapp, II , Edward Gillen
发明人： Margaret Taylor , James Bates , Roman Tunkel , Jay Butterbrodt , Gary Searle , Joshua Horvath , Keith Knapp, II , Edward Gillen
CPC分类号： A61M5/2425 , A61M5/2459 , A61M5/3287 , A61M5/425 , A61M2005/005 , A61M2005/206
摘要： A drug delivery device (100) for administering a low dose of a medicament includes a housing (111) and a drug reservoir (101) disposed in the housing (111). A needle (135) is connected to the drug reservoir (101). A pressure applying member (113) is movably connected to the housing (111) and is movable between first and second positions. The pressure applying member (113) does not apply pressure to the drug reservoir (101) in the first position and applies pressure to the drug reservoir (101) in the second position to dispense medicament stored in the drug reservoir (101). A method of administering a low dose of insulin to simulate a first-phase insulin response of a pancreas is also disclosed.
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公开(公告)号：US20130006216A1
公开(公告)日：2013-01-03
申请号：US13261383
申请日：2011-01-31
申请人： Margaret Taylor , James Bates , Roman Tunkel , Jay Butterbrodt , Gary Searle , Joshua Horvath , Keith Knapp, II , Edward Gillen
发明人： Margaret Taylor , James Bates , Roman Tunkel , Jay Butterbrodt , Gary Searle , Joshua Horvath , Keith Knapp, II , Edward Gillen
CPC分类号： A61M5/2425 , A61M5/2459 , A61M5/3287 , A61M5/425 , A61M2005/005 , A61M2005/206
摘要： A drug delivery device (100) for administering a low dose of a medicament includes a housing (111) and a drug reservoir (101) disposed in the housing (111). A needle (135) is connected to the drug reservoir (101). A pressure applying member (113) is movably connected to the housing (111) and is movable between first and second positions. The pressure applying member (113) does not apply pressure to the drug reservoir (101) in the first position and applies pressure to the drug reservoir (101) in the second position to dispense medicament stored in the drug reservoir (101). A method of administering a low dose of insulin to simulate a first-phase insulin response of a pancreas is also disclosed.
摘要翻译： 用于施用低剂量药物的药物递送装置（100）包括设置在壳体（111）中的壳体（111）和药物储存器（101）。 针（135）连接到药物储存器（101）。 压力施加构件（113）可移动地连接到壳体（111）并且可在第一和第二位置之间移动。 压力施加构件（113）在第一位置不对药物储存器（101）施加压力，并且在第二位置向药物储存器（101）施加压力以分配存储在药物储存器（101）中的药物。 还公开了施用低剂量胰岛素以模拟胰腺的第一阶段胰岛素反应的方法。
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公开(公告)号：US20120179115A1
公开(公告)日：2012-07-12
申请号：US13261197
申请日：2010-09-15
申请人： Joshua Horvath , Joseph Brizzolara , Charles Hwang , James Bates , Keith Knapp
发明人： Joshua Horvath , Joseph Brizzolara , Charles Hwang , James Bates , Keith Knapp
CPC分类号： A61M5/3205 , A61M5/3293 , A61M5/344 , A61M2005/3206 , A61M2005/3279 , Y10T29/49815 , Y10T29/53991
摘要： A pen needle (101) for use with a drug delivery device (100) includes a hub body (113) having internal threads (216) to receive the drug delivery device (100). A post (121) is connected to the hub body (113). A needle (103) is rigidly fixed to the post (121). The post (121) is separable from the hub body (113) such that the needle (103) is removed with the post (121). The fluid path is not disturbed by such removal because the entire needle (103) is removed with the post (121). Removal of only the post (121) and needle (103) reduces the volume of waste required for disposal, thereby increasing the effective capacity of a sharps container.
摘要翻译： 用于药物输送装置（100）的笔针（101）包括具有用于接收药物输送装置（100）的内螺纹（216）的毂体（113）。 柱体（121）连接到轮毂主体（113）。 针（103）刚性地固定到柱（121）上。 柱121可以与轮毂体113分离，使得针（103）与柱（121）一起移除。 由于整个针（103）用柱（121）移除，流体路径不会被这种移除所扰乱。 仅去除柱（121）和针（103）减少了处理所需的废物体积，从而增加了锐器容器的有效容量。
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公开(公告)号：US10022504B2
公开(公告)日：2018-07-17
申请号：US13261197
申请日：2010-09-15
申请人： Joshua Horvath , Joseph Brizzolara , Charles Hwang , James Bates , Keith Knapp
发明人： Joshua Horvath , Joseph Brizzolara , Charles Hwang , James Bates , Keith Knapp
摘要： A pen needle (101) for use with a drug delivery device (100) includes a hub body (113) having internal threads (216) to receive the drug delivery device (100). A post (121) is connected to the hub body (113). A needle (103) is rigidly fixed to the post (121). The post (121) is separable from the hub body (113) such that the needle (103) is removed with the post (121). The fluid path is not disturbed by such removal because the entire needle (103) is removed with the post (121). Removal of only the post (121) and needle (103) reduces the volume of waste required for disposal, thereby increasing the effective capacity of a sharps container.
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公开(公告)号：US20120041383A1
公开(公告)日：2012-02-16
申请号：US13206405
申请日：2011-08-09
申请人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
发明人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
CPC分类号： A61M5/008 , A61M2005/004
摘要： An apparatus is disclosed for storing and changing needles for a medicament delivery device having a medicament container, including a fixed mount for connecting the apparatus with the medicament delivery device, a needle holder displaceable along a circuitous path and connecting a plurality of needles displaceably disposed thereon, and a guide member for guiding displacement of the needle holder, the guide member being disposed about the fixed mount. The apparatus also includes a user interface rotatably disposed about the fixed mount and having at least one internal engaging structure for displacing the needle holder along the circuitous path.
摘要翻译： 公开了一种用于存储和更换用于具有药物容器的药物输送装置的针的装置，其包括用于将装置与药物输送装置连接的固定支架，可沿着迂回路径移位并连接可移动地设置在其上的多个针的针保持器 以及用于引导针保持器的位移的引导构件，所述引导构件围绕固定座设置。 该装置还包括可旋转地设置在固定安装件周围的用户界面，并且具有至少一个内部接合结构，用于沿着迂回路径移动针保持器。
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公开(公告)号：US09107988B2
公开(公告)日：2015-08-18
申请号：US13206405
申请日：2011-08-09
申请人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
发明人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
IPC分类号： A61M5/00
CPC分类号： A61M5/008 , A61M2005/004
摘要： An apparatus is disclosed for storing and changing needles for a medicament delivery device having a medicament container, including a fixed mount for connecting the apparatus with the medicament delivery device, a needle holder displaceable along a circuitous path and connecting a plurality of needles displaceably disposed thereon, and a guide member for guiding displacement of the needle holder, the guide member being disposed about the fixed mount. The apparatus also includes a user interface rotatably disposed about the fixed mount and having at least one internal engaging structure for displacing the needle holder along the circuitous path.
摘要翻译： 公开了一种用于存储和更换用于具有药物容器的药物输送装置的针的装置，其包括用于将装置与药物输送装置连接的固定支架，可沿着迂回路径移动并连接可移动地设置在其上的多个针的针保持器 以及用于引导针保持器的位移的引导构件，所述引导构件围绕固定座设置。 该装置还包括一个可旋转地设置在固定安装件周围的用户界面，并具有至少一个用于沿着迂回路径移动针座的内部接合结构。
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公开(公告)号：US20120041385A1
公开(公告)日：2012-02-16
申请号：US13206469
申请日：2011-08-09
IPC分类号： A61M5/32
CPC分类号： A61M5/002 , A61M5/34 , A61M5/343 , A61M2005/004
摘要： An attachable needle storage device is provided with a main body and a rotatable sleeve and a plurality of new needles stored within the sleeve, a leaf spring to direct each needle into a circumferential position of the pen body when rotated, and a ramp to move the needle into an axial position of the pen body when retracted or pulled rearward by the user. The attachable needle storage device is configured to attach to a pen device in a manner substantially the same as a conventional needle hub. In doing so, the rotation of the sleeve can be used to rotate a new needle onto a shuttle, and the retraction of the device can be used to cause a ramp to engage the needle and needle hub, moving the needle toward the axial position of the pen body and the septum. Once under the septum, the user continues pulling the device rearward, such that the needle is then moved rearward, pierces the septum of the medicament cartridge and exposes the distal end of the needle for injection. After use, a needle shield is used to unlock a compressed spring, which is configured to pull the needle from the septum, and return the device to the transport state, after which the previous steps can be repeated.
摘要翻译： 可附接的针存储装置设置有主体和可旋转的套筒以及存储在套筒内的多个新针，一个板簧，用于将每个针定位成旋转时的笔体周向位置，并且使斜坡移动 当用户收回或向后拉时，针头进入笔体的轴向位置。 可连接针存储装置被配置为以与常规针毂基本相同的方式附接到笔式装置。 在这样做时，套筒的旋转可以用于将新的针旋转到梭子上，并且装置的缩回可以用于引起斜面接合针和针座，使针朝着轴向位置移动 笔体和隔膜。 一旦在隔膜下方，用户继续向后拉动装置，使得针随后向后移动，刺穿药剂盒的隔膜并暴露注射针的远端。 使用后，使用针护罩来解锁压缩弹簧，压缩弹簧被配置为从隔膜拉动针头，并将装置返回到运输状态，之后可以重复前述步骤。
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公开(公告)号：US20120041373A1
公开(公告)日：2012-02-16
申请号：US13206438
申请日：2011-08-09
申请人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
发明人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
IPC分类号： A61M5/32
CPC分类号： A61M5/002 , A61B5/150389 , A61M5/3205 , A61M5/3243 , A61M5/3298 , A61M2005/004 , A61M2005/312
摘要： An apparatus is disclosed for storing and changing needles for connection with a medicament delivery device, comprising an inner housing, a reservoir disposed within the inner housing, and a needle holder disposed within the inner housing, for fluidly connecting a medicament container of the medicament delivery device with the reservoir. The apparatus also includes a plurality of patient needles displaceably disposed on the needle holder, and an outer housing displaceably disposed about the inner housing and providing a user interface to individually select one of the plurality of patient needles, connect the selected needle with the reservoir, expose the selected needle outside of the apparatus for injection, and store the selected needle.
摘要翻译： 公开了一种用于存储和更换用于与药物输送装置连接的针的装置，包括内部壳体，设置在内部壳体内的储存器和设置在内部壳体内的针保持器，用于将药物输送物的药物容器流体连接 装置与水库。 该装置还包括可移动地设置在针保持器上的多个患者针和可围绕内壳可移动地设置的外壳，并且提供用户界面以单独选择多个患者针中的一个，将所选择的针与储存器连接， 将所选择的针暴露在注射装置外部，并存储所选择的针。
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公开(公告)号：US09427514B2
公开(公告)日：2016-08-30
申请号：US13206438
申请日：2011-08-09
申请人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
发明人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
CPC分类号： A61M5/002 , A61B5/150389 , A61M5/3205 , A61M5/3243 , A61M5/3298 , A61M2005/004 , A61M2005/312
摘要： An apparatus is disclosed for storing and changing needles for connection with a medicament delivery device, comprising an inner housing, a reservoir disposed within the inner housing, and a needle holder disposed within the inner housing, for fluidly connecting a medicament container of the medicament delivery device with the reservoir. The apparatus also includes a plurality of patient needles displaceably disposed on the needle holder, and an outer housing displaceably disposed about the inner housing and providing a user interface to individually select one of the plurality of patient needles, connect the selected needle with the reservoir, expose the selected needle outside of the apparatus for injection, and store the selected needle.
摘要翻译： 公开了一种用于存储和更换用于与药物输送装置连接的针的装置，包括内部壳体，设置在内部壳体内的储存器和设置在内部壳体内的针保持器，用于将药物输送物的药物容器流体连接 装置与水库。 该装置还包括可移动地设置在针保持器上的多个患者针和可围绕内壳可移动地设置的外壳，并且提供用户界面以单独选择多个患者针中的一个，将所选择的针与储存器连接， 将所选择的针暴露在注射装置外部，并存储所选择的针。
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公开(公告)号：US08827956B2
公开(公告)日：2014-09-09
申请号：US13127454
申请日：2009-11-06
申请人： Robert Banik , James Bates
发明人： Robert Banik , James Bates
IPC分类号： A61M5/00
CPC分类号： A61M5/3287 , A61M5/1782 , A61M5/46
摘要： A syringe (211) includes a syringe body (217) for receiving and administering a medicament. A needle (215) is received by the syringe body (217). A needle adjusting member (221) is movably disposed on the syringe body (217) between first and second positions. When the needle adjusting member (221) is in the first position, the needle (215) has a first length adapted to draw medicament into the syringe body (217). When the needle adjusting member (221) is in the second position, the needle (215) has a second length for injecting the medicament.
摘要翻译： 注射器（211）包括用于接收和施用药物的注射器主体（217）。 针（215）由注射器主体（217）容纳。 针调节构件（221）在第一和第二位置之间可动地设置在注射器主体（217）上。 当针调节构件（221）处于第一位置时，针（215）具有适于将药剂吸入注射器主体（217）的第一长度。 当针调节构件（221）处于第二位置时，针（215）具有用于注射药物的第二长度。
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