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公开(公告)号：US09821116B2
公开(公告)日：2017-11-21
申请号：US14235107
申请日：2012-07-25
CPC分类号： A61M5/20 , A61M5/14248 , A61M5/158 , A61M5/2033 , A61M5/282 , A61M5/31 , A61M5/3286 , A61M2005/14252 , A61M2005/206 , A61M2005/2073 , A61M2205/50 , F04C2270/0421
摘要： A fluid dispensing device is provided for dispensing a measured amount of fluid into a living organism. The device has a needle having a first end and a second end. The needle is adapted for interfacing, on the first end, with a septum of a flexible hollow membrane, and at a second end thereof, for subcutaneously inserting into a living organism. The needle is guided by a guide to permit an injection into the living organism at a substantially non-orthogonal angle with respect to a surface of the living organism. The first and second ends of the needle pierce their respective piercing surface while translating together in a common direction. In other embodiments, the dispensing device includes a main housing, a flexible fluid reservoir, an injection assembly and a trigger mechanism. The main housing houses the operative components of the device.
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公开(公告)号：US09427514B2
公开(公告)日：2016-08-30
申请号：US13206438
申请日：2011-08-09
申请人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
发明人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
CPC分类号： A61M5/002 , A61B5/150389 , A61M5/3205 , A61M5/3243 , A61M5/3298 , A61M2005/004 , A61M2005/312
摘要： An apparatus is disclosed for storing and changing needles for connection with a medicament delivery device, comprising an inner housing, a reservoir disposed within the inner housing, and a needle holder disposed within the inner housing, for fluidly connecting a medicament container of the medicament delivery device with the reservoir. The apparatus also includes a plurality of patient needles displaceably disposed on the needle holder, and an outer housing displaceably disposed about the inner housing and providing a user interface to individually select one of the plurality of patient needles, connect the selected needle with the reservoir, expose the selected needle outside of the apparatus for injection, and store the selected needle.
摘要翻译： 公开了一种用于存储和更换用于与药物输送装置连接的针的装置，包括内部壳体，设置在内部壳体内的储存器和设置在内部壳体内的针保持器，用于将药物输送物的药物容器流体连接 装置与水库。 该装置还包括可移动地设置在针保持器上的多个患者针和可围绕内壳可移动地设置的外壳，并且提供用户界面以单独选择多个患者针中的一个，将所选择的针与储存器连接， 将所选择的针暴露在注射装置外部，并存储所选择的针。
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公开(公告)号：US08795230B2
公开(公告)日：2014-08-05
申请号：US13303055
申请日：2011-11-22
IPC分类号： A61M5/00
CPC分类号： A61M5/46 , A61M5/158 , A61M5/488 , A61M2005/14252 , A61M2005/14264 , A61M2005/1581 , A61M2005/1585 , A61M2005/1586 , A61M2005/1587 , A61M2005/3289
摘要： An infusion set has a retraction dial that can be removably assembled with the infusion set and access a threaded needle hub contained therein such that the dial can be used to advance or retract a needle hub and an inserted needle to a more precisely controlled insertion depth to deliver insulin or other medicament intradermally (i.e. to the upper 3 mm of skin surface). Position of the inserted needle can be maintained by providing a separated and isolated needle hub, main base and main hub of the infusion set that can isolate the inserted needle from external forces such that the needle can be maintained at a depth to deliver content to the upper 3 mm of skin surface during normal use.
摘要翻译： 输液器具有可以与输液器组合并且进入其中包含的螺纹针毂的退回拨盘，使得该拨盘可用于使针座和插入的针前进或缩回以更准确地控制的插入深度 皮内递送胰岛素或其他药物（即皮肤表面的上部3mm）。 可以通过提供分离和隔离的针座，输液装置的主底座和主轮毂来保持插入的针的位置，其可以将插入的针与外力隔离，使得针可以保持在深度以将内容物输送到 正常使用时皮肤表面上方3 mm。
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公开(公告)号：US20140031793A1
公开(公告)日：2014-01-30
申请号：US13983992
申请日：2012-02-08
CPC分类号： A61M5/158 , A61B17/3415 , A61B17/3496 , A61M5/14248 , A61M25/0606 , A61M25/0631 , A61M2005/1585 , A61M2005/1586
摘要： An infusion set (201) includes a base (221) and a flexible catheter (242) movable from a first catheter position disposed substantially entirely within the base (221) to a second catheter position in which a free end of the catheter (242) is disposed externally of the base (221). An introducer needle (234) is located within the catheter (242) and is movable between a first introducer needle position disposed substantially entirely within the base (221) and a second introducer needle position in which a free end of the introducer needle (234) is disposed externally of the base (221). A torsion spring (281) is activated to move the catheter (242) from the first to the second catheter position and the introducer needle (234) from the first to the second introducer needle position to facilitate insertion of the catheter (242). The introducer needle (234) is thereafter moved by the torsion spring (281) back to the first introducer needle position to store the introducer needle (234) within the base (221) with the free end of the catheter (242) remaining disposed externally of the base (221).
摘要翻译： 输液器（201）包括基部（221）和可从基本上完全设置在基座（221）内的第一导管位置移动到第二导管位置的柔性导管（242），其中导管（242）的自由端 设置在基座（221）的外部。 引导器针（234）位于导管（242）内，并且可在基本上完全设置在基座（221）内的第一引导器针位置和第二导引针位置之间移动，其中导引针（234）的自由端 设置在基座（221）的外部。 扭转弹簧（281）被启动以使导管（242）从第一导管位置和导引器针头（234）从第一导引器针位置移动到第二导引器针位置，以便于插入导管（242）。 导引针（234）此后由扭力弹簧（281）移动回第一导引针位置，以将引导器针（234）存储在基座（221）内，导管（242）的自由端保持在外部 的基座（221）。
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公开(公告)号：US20120004641A1
公开(公告)日：2012-01-05
申请号：US12998853
申请日：2009-12-08
IPC分类号： A61M5/31
CPC分类号： A61M5/31553 , A61M5/19 , A61M5/204 , A61M5/31511 , A61M5/484 , A61M2005/3128
摘要： A dual-chambered drug delivery device (201) includes a first chamber (205) in which a medicament is stored. A dose setting member (213) is rotated to set a medicament dose. The dose setting member (213) being rotatable to set the medicament dose. The dose setting member (213) is not axially moveable. A second chamber (221) is in fluid communication with the first chamber (205). The medicament dose is transferred to the second chamber (221) from the first chamber (205) prior to injecting the medicament dose. A needle (203) communicates with the second chamber (221) to inject the medicament dose into an injection site.
摘要翻译： 双室药物输送装置（201）包括其中储存药物的第一腔室（205）。 旋转剂量设定构件（213）以设定药物剂量。 剂量设定构件（213）可旋转以设定药物剂量。 剂量设定构件（213）不能轴向移动。 第二室（221）与第一室（205）流体连通。 在注射药物剂量之前，药物剂量从第一腔室（205）转移到第二腔室（221）。 针（203）与第二腔（221）连通以将药剂剂量注入注射部位。
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6.发明申请LEVER AND GEAR FORCE MULTIPLIER MEDICATION DELIVERY SYSTEM FOR HIGH PRESSURE INJECTION SYSTEM 有权用于高压注射系统的杠杆和齿轮力多用途药物输送系统公开(公告)号：US20120004620A1
公开(公告)日：2012-01-05
申请号：US12998841
申请日：2009-12-08
申请人： Ira Spool , Michel Bruehwiler , Ryan Schoonmaker , Melissa Rosen
发明人： Ira Spool , Michel Bruehwiler , Ryan Schoonmaker , Melissa Rosen
IPC分类号： A61M5/315
CPC分类号： A61M5/24 , A61M5/31511 , A61M5/3155 , A61M2005/3152
摘要： A drug delivery device includes a cartridge (211) for storing a medicament and a needle (203) communicating with the cartridge (211) for injecting a medicament dose. A rack (241) is movably disposed in the cartridge (211) and is engageable with a stopper (213) for expelling the medicament dose from the cartridge (211). A lever assembly (231) has a lever arm (233) connected to a lever gear (230). The lever gear (232) is engaged with the rack (241) such that rotation of the lever arm (233) rotates the lever gear (232) during injection of the medicament dose, thereby moving the rack (241) and stopper (213) through the cartridge (211) to deliver the medicament dose.
摘要翻译： 药物输送装置包括用于储存药物的药筒（211）和与药筒（211）连通以用于注射药物剂量的针（203）。 可移动地设置在盒（211）中的齿条（241）并且可与用于从药筒（211）排出药物剂量的止动件（213）接合。 杠杆组件（231）具有连接到杠杆齿轮（230）的杠杆臂（233）。 杠杆齿轮（232）与齿条（241）接合，使得在注射药物剂量期间杠杆臂（233）的旋转使杠杆齿轮（232）旋转，从而使齿条（241）和止动器（213）移动， 通过药筒（211）以递送药物剂量。
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公开(公告)号：US09408980B2
公开(公告)日：2016-08-09
申请号：US12998853
申请日：2009-12-08
申请人： Michel Bruehwiler , Melissa Rosen , Ryan Schoonmaker , Ira Spool
发明人： Michel Bruehwiler , Melissa Rosen , Ryan Schoonmaker , Ira Spool
CPC分类号： A61M5/31553 , A61M5/19 , A61M5/204 , A61M5/31511 , A61M5/484 , A61M2005/3128
摘要： A dual-chambered drug delivery device (201) includes a first chamber (205) in which a medicament is stored. A dose setting member (213) is rotated to set a medicament dose. The dose setting member (213) being rotatable to set the medicament dose. The dose setting member (213) is not axially moveable. A second chamber (221) is in fluid communication with the first chamber (205). The medicament dose is transferred to the second chamber (221) from the first chamber (205) prior to injecting the medicament dose. A needle (203) communicates with the second chamber (221) to inject the medicament dose into an injection site.
摘要翻译： 双室药物输送装置（201）包括其中储存药物的第一腔室（205）。 旋转剂量设定构件（213）以设定药物剂量。 剂量设定构件（213）可旋转以设定药物剂量。 剂量设定构件（213）不能轴向移动。 第二室（221）与第一室（205）流体连通。 在注射药物剂量之前，药物剂量从第一腔室（205）转移到第二腔室（221）。 针（203）与第二腔（221）连通以将药剂剂量注入注射部位。
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8.发明授权Robotic end effector for frozen aliquotter and methods of taking a frozen aliquot from biological samples 有权用于冷冻等分试样的机器人末端效应器和从生物样品中取出冷冻等分试样的方法公开(公告)号：US09134202B2
公开(公告)日：2015-09-15
申请号：US13359301
申请日：2012-01-26
CPC分类号： G01N1/08 , B25J15/0019 , G01F17/00 , G01N1/42 , G01N35/0099 , G01N35/10 , G01N2035/1025 , Y10S901/41
摘要： A robotic end effector for collecting frozen aliquots from an array of frozen samples in a plurality of containers has a coring bit for taking frozen sample cores from the frozen samples and a frozen sample core extraction system adapted to extract frozen sample cores from the frozen samples. A fill level detection system is adapted to detect the positions of the surfaces of the frozen samples. A processor is adapted to receive signals from the fill level detection system and use the signals and information concerning operation of the frozen sample core extraction system to determine at least one of the following: (a) the amount of material contained in a frozen sample core obtained by the coring bit; and (b) the number of frozen sample cores needed from a particular frozen sample to obtain a predetermined amount of material from that frozen sample.
摘要翻译： 用于从多个容器中的冷冻样品阵列收集冷冻等分试样的机器人末端执行器具有用于从冷冻样品中取出冷冻样品核心的取芯钻头和适于从冷冻样品中提取冷冻样品核心的冷冻样品芯提取系统。 填充水平检测系统适于检测冷冻样品的表面的位置。 处理器适于接收来自填充水平检测系统的信号，并且使用关于冷冻样品芯提取系统的操作的信号和信息来确定以下中的至少一个：（a）冷冻样品核心中所含的材料的量 由取芯钻头获得; 和（b）特定冷冻样品所需的冷冻样品核心的数量，以从该冷冻样品获得预定量的材料。
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公开(公告)号：US09107988B2
公开(公告)日：2015-08-18
申请号：US13206405
申请日：2011-08-09
申请人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
发明人： Michel Bruehwiler , Cole Constantineau , Ryan Schoonmaker , James Bates , Margaret Taylor , Robert Banik
IPC分类号： A61M5/00
CPC分类号： A61M5/008 , A61M2005/004
摘要： An apparatus is disclosed for storing and changing needles for a medicament delivery device having a medicament container, including a fixed mount for connecting the apparatus with the medicament delivery device, a needle holder displaceable along a circuitous path and connecting a plurality of needles displaceably disposed thereon, and a guide member for guiding displacement of the needle holder, the guide member being disposed about the fixed mount. The apparatus also includes a user interface rotatably disposed about the fixed mount and having at least one internal engaging structure for displacing the needle holder along the circuitous path.
摘要翻译： 公开了一种用于存储和更换用于具有药物容器的药物输送装置的针的装置，其包括用于将装置与药物输送装置连接的固定支架，可沿着迂回路径移动并连接可移动地设置在其上的多个针的针保持器 以及用于引导针保持器的位移的引导构件，所述引导构件围绕固定座设置。 该装置还包括一个可旋转地设置在固定安装件周围的用户界面，并具有至少一个用于沿着迂回路径移动针座的内部接合结构。
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公开(公告)号：US09101724B2
公开(公告)日：2015-08-11
申请号：US13205561
申请日：2011-08-08
CPC分类号： A61M5/3205 , A61M5/002 , A61M5/003 , A61M5/3202 , A61M5/321
摘要： An apparatus is disclosed for storing and dispensing pen needles for an injection device, including a case having dispensing and storage ends for dispensing and storing a plurality of pen needles and a plurality of needle cover units, each pen needle having a patient end and a hub for connection to the injection device, and each needle cover unit having a needle-covering portion for covering a patient end and a hub-covering portion for covering a hub. A needle-covering portion covering the needle of one pen needle is coupled with a hub-covering portion covering a hub of another pen needle. Prior to use, a hub-covering portion covering the hub of a pen needle is exposed to an outside at the dispensing end of the case, and subsequent to use, the pen needle is stored in the storage end of the case.
摘要翻译： 公开了一种用于存储和分配用于注射装置的笔针的装置，包括具有用于分配和存储多个笔针的分配和存储端的壳体和多个针盖单元，每个笔针具有患者端和毂 用于连接到注射装置，并且每个针头盖单元具有用于覆盖患者端的针覆盖部分和用于覆盖轮毂的轮毂覆盖部分。 覆盖一根笔针的针的针覆盖部分与覆盖另一笔针的毂的轮毂覆盖部分联接。 在使用之前，覆盖笔针的轮毂的轮毂覆盖部分暴露在壳体的分配端处的外侧，并且在使用之后，笔针被存储在壳体的存储端中。
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