利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

5 条记录 (耗时 0.052 秒)

    Microemulsion process and composition
    1.
    发明授权
    Microemulsion process and composition 有权
    微乳液工艺及组成

    公开(公告)号：US08460641B2

    公开(公告)日：2013-06-11

    申请号：US11216668

    申请日：2005-08-31

    申请人： Maria Graziella Larm ,  Ronald Harding ,  Michael Johnston ,  Albert Zorko Abram ,  Prema Vijayakumar ,  Phoebe Sun

    发明人： Maria Graziella Larm ,  Ronald Harding ,  Michael Johnston ,  Albert Zorko Abram ,  Prema Vijayakumar ,  Phoebe Sun

    IPC分类号： A61K9/00 ,  A61K8/02 ,  A61K8/00 ,  A61K31/59 ,  A61K31/56 ,  A01N45/00

    CPC分类号： A61K31/56 ,  A61K8/062 ,  A61K8/068 ,  A61K9/0014 ,  A61K9/107 ,  A61K9/1075 ,  A61K9/12 ,  A61K31/59 ,  A61Q19/00

    摘要： An oil-in-water microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient, comprising: a first part including at least one occlusive agent and one or more lipophilic surfactants dispersed throughout a second part including water and at least one hydrophilic surfactant, and a non-surfactant amphiphilic type compound, pharmaceutically active ingredient, and water. It has been found that if a non-surfactant amphiphilic type compound is added together with the second part as would conventionally be the case, a microemulsion or sub-micron emulsion is not formed, by adding the so called third part, phase assembly occurs at a lower temperature than would be expected and moreover, this phase appears to assist in maintaining the microemulsion or sub-micron emulsion characteristics of the formulation during storage at normal temperatures.

    摘要翻译： 一种用于皮肤递送至少一种药物活性成分的水包油微乳液或亚微米乳液组合物，其包含：第一部分，其包含至少一种封闭剂和一种或多种分散在包括水的第二部分和在 至少一种亲水性表面活性剂和非表面活性剂两亲型化合物，药物活性成分和水。 已经发现如果将非表面活性剂两亲型化合物与常规情况下的第二部分一起加入，则不形成微乳液或亚微米级乳液，通过加入所谓的第三部分，相组合发生在 比预期的温度更低，此外，该阶段似乎有助于在常温下储存期间维持制剂的微乳液或亚微米乳液特性。

    Vitamin formulation
    5.
    发明授权
    Vitamin formulation 有权
    维生素配方

    公开(公告)号：US08263580B2

    公开(公告)日：2012-09-11

    申请号：US11420700

    申请日：2006-05-26

    申请人： Richard Buchta ,  Robert James Houlden ,  Rose Ye ,  Maria Graziella Larm ,  Leon Loupenok

    发明人： Richard Buchta ,  Robert James Houlden ,  Rose Ye ,  Maria Graziella Larm ,  Leon Loupenok

    IPC分类号： A61K31/59 ,  A61K31/355 ,  A61K9/12

    CPC分类号： A61K31/355 ,  A61K9/0014 ,  A61K9/122 ,  A61K31/59

    摘要： A pharmaceutical aerosol foam composition, comprising: an effective amount of a pharmaceutically active ingredient, wherein said pharmaceutically active ingredient is a vitamin or analogue thereof; an occlusive agent; an aqueous solvent; an organic cosolvent; wherein the pharmaceutically active ingredient is insoluble in both water and the occlusive agent; and the occlusive agent being present in an amount sufficient to form an occlusive layer on the skin, in use. In a second embodiment, an oil-in water emulsion having a vitamin, an occlusive agent; an aqueous solvent; and an organic cosolvent, wherein the occlusive agent is present in an amount sufficient to form an occlusive layer on the skin.

    摘要翻译： 一种药物气溶胶泡沫组合物，其包含：有效量的药物活性成分，其中所述药物活性成分是维生素或其类似物; 闭塞剂; 水溶剂; 有机助溶剂; 其中药物活性成分不溶于水和闭塞剂; 并且所述闭塞剂以足以在使用中在皮肤上形成闭塞层的量存在。 在第二个实施方案中，一种含有维生素，闭塞剂的油包水乳液; 水溶剂; 和有机共溶剂，其中所述闭塞剂以足以在皮肤上形成闭塞层的量存在。