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1.发明授权Heterogeneous topical compositions having a base of microgranules of caffeine and/or its derivatives, which can be used as slenderizer and/or in the treatment of cellulitis, as well as their preparation 失效具有咖啡因微粒和/或其衍生物的基质的非均匀局部组合物，其可用作细长剂和/或用于治疗蜂窝织炎，以及它们的制备
公开(公告)号：US4938962A
公开(公告)日：1990-07-03
申请号：US281082
申请日：1988-12-07
CPC分类号： A61K8/0241 , A61K31/52 , A61K8/4953 , A61K9/06 , A61Q19/06 , A61K2800/412
摘要： The present invention relates to a heterogeneous topical composition comprising microgranules or microparticles of a topically-acceptable caffeine metal carboxylate in a hydroalcoholic gel, as well as its preparation and use. The composition, which can be used as slenderizer and/or in the treatment of cellulitis, comprises a long acting topically-acceptable caffeine metal carboxylate as the active principle, which is present in the form of heterogeneously-distributed microgranules or microparticles, having a diameter of about 0.2 to 2 millimeters, suspended in a hydroalcoholic gel in which they are insoluble, advantageously together with Vitamin E or a derivative thereof.
摘要翻译： 本发明涉及在水醇凝胶中包含局部可接受的咖啡因金属羧酸盐的微粒或微粒的非均质局部组合物及其制备和用途。 可用作细长剂和/或治疗蜂窝织炎的组合物包含长效局部接受的咖啡因金属羧酸盐作为活性成分，其以非均匀分布的微粒或微粒的形式存在，其直径 约0.2至2毫米，悬浮在不溶于水的醇凝胶中，有利地与维生素E或其衍生物一起使用。
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2.发明授权Topical slenderizing formulation containing cafeine carboxylic acid derivatives neutralized by organic bases, preparation thereof, and their use in the treatment of cellulite 失效含有有机碱中和的咖啡因羧酸衍生物的局部细长制剂及其制备方法及其在处理脂肪团中的应用
公开(公告)号：US5030451A
公开(公告)日：1991-07-09
申请号：US442807
申请日：1989-11-29
IPC分类号： A61K8/49 , A61Q19/06 , C07D473/08
CPC分类号： C07D473/08 , A61K8/4953 , A61Q19/06
摘要： The present invention relates to topical compositions containing caffeine carboxylates with organic bases, which are useful as slenderizing agents and in the treatment of cellulitis, as well as their preparation.The heterogeneous topical compositions of the invention contain, as active principle, a caffeine carboxylic acid which has been salified with a cosmetologically-acceptable organic base, the active principle preferably being present in the form of microparticles or microgranules suspended in a hydroalcoholic gel.
摘要翻译： 本发明涉及含有咖啡因羧酸盐与有机碱的局部组合物，其可用作熟化剂和用于治疗蜂窝织炎及其制备。 作为活性成分，本发明的异质局部组合物含有已经用美容学可接受的有机碱成盐的咖啡因羧酸，活性成分优选以悬浮在水醇凝胶中的微粒或微粒的形式存在。
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公开(公告)号：US5376379A
公开(公告)日：1994-12-27
申请号：US66111
申请日：1993-06-04
IPC分类号： A61K8/19 , A61K8/11 , A61K8/14 , A61K8/33 , A61K8/36 , A61K8/41 , A61K8/60 , A61K8/72 , A61K8/96 , A61K8/97 , A61K9/127 , A61K33/00 , A61K35/08 , A61K36/00 , A61K47/34 , A61Q19/00 , B01J13/02
CPC分类号： A61K8/606 , A61K35/08 , A61K47/34 , A61K8/14 , A61K8/965 , A61K9/127 , A61Q19/00 , Y10T428/2984
摘要： The present invention relates to compositions based on thermal water containing liposomes of thermal water stabilized in a deoxyribonucleic acid (DNA) gel and a process for preparing thereof. The composition is useful in dermatology and cosmetology.
摘要翻译： PCT No.PCT / FR91 / 00805 Sec。 371日期：1993年6月4日 102（e）日期1993年6月4日PCT 1991年10月16日PCT PCT。 出版物WO92 / 06666 本发明涉及基于含有在脱氧核糖核酸（DNA）凝胶中稳定的热水脂质体的热水的组合物及其制备方法。 该组合物可用于皮肤科和美容。
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公开(公告)号：US6054138A
公开(公告)日：2000-04-25
申请号：US952647
申请日：1997-11-21
IPC分类号： A61K8/00 , A61K8/06 , A61K8/29 , A61K8/30 , A61K8/31 , A61K8/34 , A61K8/37 , A61K8/41 , A61K8/72 , A61K8/73 , A61K8/81 , A61K8/89 , A61K8/891 , A61K8/92 , A61K8/97 , A61K9/06 , A61K9/107 , A61K47/36 , A61Q1/02 , A61Q1/14 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61K7/00 , A61K7/42 , A61K31/74 , A61K47/00
CPC分类号： A61K8/06 , A61K9/06 , A61K9/107 , A61Q17/00 , A61Q19/00 , A61Q17/04 , A61Q19/005 , A61Q19/007 , Y10S514/844 , Y10S514/937
摘要： The present invention relates to a pharmaceutical and/or cosmetic composition in the form of a stabilized pseudoemulsion, characterized in that it is essentially comprised of (1) at least one aqueous phase containing a single gelifying agent selected from the group comprising polyoses, such as gelose, the xanthane gums, cellulose, alginates, semisynthetic derivatives of cellulose, and acrylic polymers such as Synthalen.RTM.; (2) at least one lipidic phase containing at least one consistency factor, with a ratio consistency factor/total lipidic phase between about 0.06 and 0.18, and in that said composition is free of surfactants. It also relates to a process for preparing such composition.
摘要翻译： PCT No.PCT / FR96 / 00756 Sec。 371日期：1997年11月21日 102（e）1997年11月21日日期PCT提交1996年5月21日PCT公布。 WO96 / 37180 PCT出版物 日本1996年11月28日本发明涉及稳定的假乳剂形式的药物和/或化妆品组合物，其特征在于其基本上由（1）至少一种含有单一凝胶剂的水相，所述单一凝胶剂选自 包括多糖，例如粗糖，黄原胶，纤维素，藻酸盐，纤维素的半合成衍生物和丙烯酸聚合物如Synthalen TM; （2）至少一种含有至少一种稠度因子的脂质相，其比例稠度因子/总脂质相在约0.06至0.18之间，并且所述组合物不含表面活性剂。 它还涉及制备这种组合物的方法。
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