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1.
公开(公告)号:US20120264693A1
公开(公告)日:2012-10-18
申请号:US13377773
申请日:2010-06-11
IPC分类号: A61K38/12 , C12N5/07 , A61P9/00 , A61P17/00 , A61P27/02 , A61P13/10 , A61P19/10 , A61P13/12 , A61P35/00 , A61P19/00 , A61P13/02 , C07K7/64 , A61P25/00
CPC分类号: G01N33/5032 , A61K38/00 , C07K7/64
摘要: Compounds capable of modulating intracellular gap junctional communication, as well as their use in the treatment of diseases associated with impaired gap junction intracellular communication (GJIC) 1 are disclosed.
摘要翻译: 公开了能够调节细胞间隙连接通讯的化合物及其在治疗与间隙连接细胞内通讯(GJIC)1相关的疾病中的用途。
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公开(公告)号:US20100298225A1
公开(公告)日:2010-11-25
申请号:US12669351
申请日:2008-07-14
IPC分类号: A61K38/16 , C07K14/00 , C07K7/06 , A61P9/00 , C07K7/08 , A61P29/00 , A61K38/10 , A61K38/08 , A61P27/16 , A61P13/10 , A61P13/12 , A61P25/00 , A61P37/06 , A61P35/00 , A61P11/00
CPC分类号: C07K14/705 , A61K38/00 , C07K5/0817 , C07K5/1019
摘要: Disclosed are peptides that facilitate the intercellular communication mediated by gap junctions. The invention has a wide spectrum of useful applications including use in the treatment of diseases associated with impaired gap junction intracellular communication (GJIC).
摘要翻译: 公开了促进由间隙连接介导的细胞间通讯的肽。 本发明具有广泛的有用应用,包括用于治疗与间隙连接细胞内通讯(GJIC)相关的疾病。
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