公开(公告)号：US08853472B2

公开(公告)日：2014-10-07

申请号：US13318557

申请日：2010-05-07

申请人： Mario Joseph Nappa ,  Patricia Cheung ,  Karl R. Krause ,  Michael A. Sisk

发明人： Mario Joseph Nappa ,  Patricia Cheung ,  Karl R. Krause ,  Michael A. Sisk

IPC分类号： C07C17/38 ,  C07C17/25

CPC分类号： C07C17/25 ,  C07C21/18

摘要： A process is disclosed for reducing the amount of monofluoroacetate. The process involves (a) contacting a hydrofluorocarbon with a reactant basic aqueous solution to produce an organic phase solution containing a hydrofluoroolefin and an aqueous phase solution containing a monofluoroacetate; and (b) heating the aqueous phase solution to an effective temperature to reduce the amount of monofluoroacetate in the aqueous phase solution, wherein fluoride concentration in the aqueous phase solution is substantially high. Another process is disclosed for reducing the amount of monofluoroacetate. The process involves (a) contacting a first batch of hydrofluorocarbon with a first batch of reactant basic aqueous solution to produce a first batch of organic phase solution containing a hydrofluoroolefin and a first batch of aqueous phase solution containing a monofluoroacetate; (b) separating the first batch of organic phase solution from the first batch of aqueous phase solution; (c) mixing a second batch of hydrofluorocarbon and a second batch of reactant basic aqueous solution with the separated first batch of organic phase solution to produce a second batch of organic phase solution containing a hydrofluoroolefin and a second batch of aqueous phase solution containing a monofluoroacetate; (d) combining the first batch of aqueous phase solution with the second batch of aqueous phase solution; and (e) heating the combined aqueous phase solutions to an effective temperature to reduce the amount of monofluoroacetate in the combined aqueous phase solutions, wherein fluoride concentration in the combined aqueous phase solutions is substantially high.

摘要翻译： 公开了一种减少一氟乙酸盐的量的方法。 该方法包括（a）使氢氟烃与反应性碱性水溶液接触以产生含有氢氟烯烃和含有一氟乙酸盐的水相溶液的有机相溶液; 和（b）将水相溶液加热到有效温度以降低水相溶液中的一氟乙酸盐的量，其中水相溶液中的氟化物浓度基本上高。 公开了用于减少一氟乙酸盐的量的另一种方法。 该方法包括（a）使第一批氢氟烃与第一批反应性碱性水溶液接触，以产生含有氢氟烯烃和含有一氟乙酸盐的第一批含水相溶液的第一批有机相溶液; （b）从第一批水相溶液中分离出第一批有机相溶液; （c）将第二批氢氟烃和第二批反应性碱性水溶液与分离的第一批有机相溶液混合以产生含有氢氟烯烃的第二批有机相溶液和含有一氟乙酸盐的第二批含水相溶液 ; （d）将第一批水相溶液与第二批水相溶液组合; 和（e）将组合的水相溶液加热到有效温度以减少组合的水相溶液中的一氟乙酸盐的量，其中组合的水相溶液中的氟化物浓度基本上高。

公开(公告)号：US20120046505A1

公开(公告)日：2012-02-23

申请号：US13318557

申请日：2010-05-07

申请人： Mario Joseph Nappa ,  Patricia Cheung ,  Karl R. Krause ,  Michael A. Sisk

发明人： Mario Joseph Nappa ,  Patricia Cheung ,  Karl R. Krause ,  Michael A. Sisk

IPC分类号： C07C17/395

CPC分类号： C07C17/25 ,  C07C21/18

摘要： A process is disclosed for reducing the amount of monofluoroacetate. The process involves (a) contacting a hydrofluorocarbon with a reactant basic aqueous solution to produce an organic phase solution containing a hydrofluoroolefin and an aqueous phase solution containing a monofluoroacetate; and (b) heating the aqueous phase solution to an effective temperature to reduce the amount of monofluoroacetate in the aqueous phase solution, wherein fluoride concentration in the aqueous phase solution is substantially high. Another process is disclosed for reducing the amount of monofluoroacetate. The process involves (a) contacting a first batch of hydrofluorocarbon with a first batch of reactant basic aqueous solution to produce a first batch of organic phase solution containing a hydrofluoroolefin and a first batch of aqueous phase solution containing a monofluoroacetate; (b) separating the first batch of organic phase solution from the first batch of aqueous phase solution; (c) mixing a second batch of hydrofluorocarbon and a second batch of reactant basic aqueous solution with the separated first batch of organic phase solution to produce a second batch of organic phase solution containing a hydrofluoroolefin and a second batch of aqueous phase solution containing a monofluoroacetate; (d) combining the first batch of aqueous phase solution with the second batch of aqueous phase solution; and (e) heating the combined aqueous phase solutions to an effective temperature to reduce the amount of monofluoroacetate in the combined aqueous phase solutions, wherein fluoride concentration in the combined aqueous phase solutions is substantially high.

摘要翻译： 公开了一种减少一氟乙酸盐的量的方法。 该方法包括（a）使氢氟烃与反应性碱性水溶液接触以产生含有氢氟烯烃和含有一氟乙酸盐的水相溶液的有机相溶液; 和（b）将水相溶液加热到有效温度以降低水相溶液中的一氟乙酸盐的量，其中水相溶液中的氟化物浓度基本上高。 公开了用于减少一氟乙酸盐的量的另一种方法。 该方法包括（a）使第一批氢氟烃与第一批反应性碱性水溶液接触，以产生含有氢氟烯烃和含有一氟乙酸盐的第一批含水相溶液的第一批有机相溶液; （b）从第一批水相溶液中分离出第一批有机相溶液; （c）将第二批氢氟烃和第二批反应性碱性水溶液与分离的第一批有机相溶液混合以产生含有氢氟烯烃的第二批有机相溶液和含有一氟乙酸盐的第二批含水相溶液 ; （d）将第一批水相溶液与第二批水相溶液组合; 和（e）将组合的水相溶液加热到有效温度以减少组合的水相溶液中的一氟乙酸盐的量，其中组合的水相溶液中的氟化物浓度基本上高。

公开(公告)号：US20060287551A1

公开(公告)日：2006-12-21

申请号：US11417415

申请日：2006-05-03

申请人： Patricia Cheung ,  Enrique Iglesia ,  John Sunley ,  Aditya Bhan ,  David Law

发明人： Patricia Cheung ,  Enrique Iglesia ,  John Sunley ,  Aditya Bhan ,  David Law

IPC分类号： C07C67/36

CPC分类号： C07C51/09 ,  C07C67/37 ,  C07C53/08 ,  C07C69/14

摘要： A product comprising a lower alkyl ester of a lower aliphatic carboxylic acid is produced by a process comprising reacting a lower alkyl ether with carbon monoxide in the presence of a catalyst comprising mordenite and/or ferrierite, optionally including an additional framework metal such as gallium, boron and/or iron, under substantially anhydrous conditions. More specifically, methyl acetate is selectively produced by reaction of dimethyl ether with carbon monoxide in the presence of a catalyst comprising mordenite or ferrierite, under substantially anhydrous conditions.

摘要翻译： 包含低级脂族羧酸的低级烷基酯的产物是通过包括在包含丝光沸石和/或镁碱沸石的催化剂存在下使低级烷基醚与一氧化碳反应的方法制备的，任选地包括另外的骨架金属如镓， 硼和/或铁。 更具体地说，在基本上无水条件下，在包含丝光沸石或镁碱沸石的催化剂的存在下，通过二甲醚与一氧化碳反应选择性地生产乙酸甲酯。

公开(公告)号：US07465822B2

公开(公告)日：2008-12-16

申请号：US11639420

申请日：2006-12-15

申请人： Patricia Cheung ,  Enrique Iglesia ,  John Glenn Sunley ,  David John Law ,  Aditya Bhan

发明人： Patricia Cheung ,  Enrique Iglesia ,  John Glenn Sunley ,  David John Law ,  Aditya Bhan

IPC分类号： C07C67/36 ,  C07C51/10

CPC分类号： C07C51/09 ,  C07C67/37 ,  C07C53/08 ,  C07C69/14

摘要： A product comprising a lower alkyl ester of a lower aliphatic carboxylic acid is produced by a process comprising reacting under substantially anhydrous conditions a lower alkyl ether with carbon monoxide in the presence of a zeolite catalyst having an 8-member ring channel which is interconnected with a channel defined by a ring with greater than or equal to 8 members, the 8-member ring having a window size of at least 2.5 Angstroms×at least 3.6 Angstroms and at least one Brønsted acid site and the zeolite having a silica:X2O3 ratio of at least 5, wherein X is selected from aluminum, boron, iron, gallium and mixtures thereof.

摘要翻译： 包含低级脂族羧酸的低级烷基酯的产物是通过包括在基本上无水条件下使低级烷基醚与一氧化碳在具有8元环通道的沸石催化剂存在下反应的方法制得的，所述沸石催化剂与 通道由大于或等于8个构件的环限定，8元环的窗口尺寸至少为2.5埃至少为3.6埃和至少一个布朗斯台德酸位点，并且具有至少二氧化硅：X 2 O 3比的沸石 5，其中X选自铝，硼，铁，镓及其混合物。

公开(公告)号：US09598336B2

公开(公告)日：2017-03-21

申请号：US14115661

申请日：2012-05-16

申请人： Patricia Cheung ,  Allen Capron Sievert ,  Concetta Lamarca

发明人： Patricia Cheung ,  Allen Capron Sievert ,  Concetta Lamarca

IPC分类号： C07C17/354 ,  B01J23/44 ,  B01J35/10 ,  B01J21/04

CPC分类号： C07C17/354 ,  B01J21/04 ,  B01J23/44 ,  B01J35/1009 ,  C07C19/08

摘要： A hydrogenation process is disclosed. The process involves reacting a fluoroolefin with H2 in a reaction zone in the presence of a palladium catalyst to produce a hydrofluoroalkane product, wherein the palladium catalyst comprises palladium supported on a carrier wherein the palladium concentration is from about 0.001 wt % to about 0.2 wt % based on the total weight of the palladium and the carrier. Also disclosed is a palladium catalyst composition consisting essentially of palladium supported on α-Al2O3 wherein the palladium concentration is from about 0.001 wt % to about 0.2 wt % based on the total weight of the palladium and the α-Al2O3. Also disclosed is a hydrogenation process comprising reacting a fluoroolefin with H2 in a reaction zone in the presence of a palladium catalyst to produce a hydrofluoroalkane product, characterized by: the palladium catalyst consisting essentially of palladium supported on α-Al2O3 wherein the palladium concentration is from about 0.001 wt % to about 0.2 wt % based on the total weight of the palladium and the α-Al2O3. Also disclosed is a hydrogenation process comprising (a) passing a mixture comprising fluoroolefin and H2 through a bed of palladium catalyst in a reaction zone wherein the palladium catalyst comprises palladium supported on a carrier; and (b) producing a hydrofluoroalkane product; characterized by: the palladium catalyst in the front of the bed having lower palladium concentration than the palladium catalyst in the back of the bed.

公开(公告)号：US20140088328A1

公开(公告)日：2014-03-27

申请号：US14115661

申请日：2012-05-16

申请人： Patricia Cheung ,  Allen Capron Sievert ,  Concetta Lamarca

发明人： Patricia Cheung ,  Allen Capron Sievert ,  Concetta Lamarca

IPC分类号： C07C17/354 ,  B01J23/44

CPC分类号： C07C17/354 ,  B01J21/04 ,  B01J23/44 ,  B01J35/1009 ,  C07C19/08

摘要： A hydrogenation process is disclosed. The process involves reacting a fluoroolefin with H2 in a reaction zone in the presence of a palladium catalyst to produce a hydrofluoroalkane product, wherein the palladium catalyst comprises palladium supported on a carrier wherein the palladium concentration is from about 0.001 wt % to about 0.2 wt % based on the total weight of the palladium and the carrier. Also disclosed is a palladium catalyst composition consisting essentially of palladium supported on α-Al2O3 wherein the palladium concentration is from about 0.001 wt % to about 0.2 wt % based on the total weight of the palladium and the α-Al2O3. Also disclosed is a hydrogenation process comprising reacting a fluoroolefin with H2 in a reaction zone in the presence of a palladium catalyst to produce a hydrofluoroalkane product, characterized by: the palladium catalyst consisting essentially of palladium supported on α-Al2O3 wherein the palladium concentration is from about 0.001 wt % to about 0.2 wt % based on the total weight of the palladium and the α-Al2O3. Also disclosed is a hydrogenation process comprising (a) passing a mixture comprising fluoroolefin and H2 through a bed of palladium catalyst in a reaction zone wherein the palladium catalyst comprises palladium supported on a carrier; and (b) producing a hydrofluoroalkane product; characterized by: the palladium catalyst in the front of the bed having lower palladium concentration than the palladium catalyst in the back of the bed.

摘要翻译： 公开了一种氢化方法。 该方法包括在钯催化剂存在下在反应区中使氟代烯烃与H 2反应以产生氢氟烷烃产物，其中钯催化剂包含负载在载体上的钯，其中钯浓度为约0.001重量％至约0.2重量％ 基于钯和载体的总重量。 还公开了一种钯催化剂组合物，其主要由负载在α-Al 2 O 3上的钯组成，其中钯的浓度为钯和α-Al 2 O 3的总重量的约0.001重量％至约0.2重量％。 还公开了一种氢化方法，其包括在钯催化剂存在下在反应区中使氟烯烃与H 2反应以产生氢氟烷烃产物，其特征在于：钯催化剂主要由负载在α-Al 2 O 3上的钯组成，其中钯浓度来自 约0.001重量％至约0.2重量％，基于钯和α-Al 2 O 3的总重量。 还公开了一种氢化方法，其包括（a）将包含氟代烯烃和H 2的混合物通过钯催化剂床在反应区中，其中钯催化剂包含负载在载体上的钯; 和（b）制备氢氟烷烃产物; 其特征在于：床的前面的钯催化剂的钯浓度低于床背部的钯催化剂。

公开(公告)号：US07309798B2

公开(公告)日：2007-12-18

申请号：US11417415

申请日：2006-05-03

申请人： Patricia Cheung ,  Enrique Iglesia ,  John Glenn Sunley ,  Aditya Bhan ,  David John Law

发明人： Patricia Cheung ,  Enrique Iglesia ,  John Glenn Sunley ,  Aditya Bhan ,  David John Law

IPC分类号： C07C67/36

CPC分类号： C07C51/09 ,  C07C67/37 ,  C07C53/08 ,  C07C69/14

摘要： A product comprising a lower alkyl ester of a lower aliphatic carboxylic acid is produced by a process comprising reacting a lower alkyl ether with carbon monoxide in the presence of a catalyst comprising mordenite and/or ferrierite, optionally including an additional framework metal such as gallium, boron and/or iron, under substantially anhydrous conditions. More specifically, methyl acetate is selectively produced by reaction of dimethyl ether with carbon monoxide in the presence of a catalyst comprising mordenite or ferrierite, under substantially anhydrous conditions.

摘要翻译： 包含低级脂族羧酸的低级烷基酯的产物是通过包括在包含丝光沸石和/或镁碱沸石的催化剂存在下使低级烷基醚与一氧化碳反应的方法制备的，任选地包括另外的骨架金属如镓， 硼和/或铁。 更具体地说，在基本上无水条件下，在包含丝光沸石或镁碱沸石的催化剂的存在下，通过二甲醚与一氧化碳反应选择性地生产乙酸甲酯。

公开(公告)号：US20070238897A1

公开(公告)日：2007-10-11

申请号：US11639420

申请日：2006-12-15

申请人： Patricia Cheung ,  Enrique Iglesia ,  John Sunley ,  David Law ,  Aditya Bhan

发明人： Patricia Cheung ,  Enrique Iglesia ,  John Sunley ,  David Law ,  Aditya Bhan

IPC分类号： C07C67/00

CPC分类号： C07C51/09 ,  C07C67/37 ,  C07C53/08 ,  C07C69/14

摘要： A product comprising a lower alkyl ester of a lower aliphatic carboxylic acid is produced by a process comprising reacting under substantially anhydrous conditions a lower alkyl ether with carbon monoxide in the presence of a zeolite catalyst having an 8-member ring channel which is interconnected with a channel defined by a ring with greater than or equal to 8 members, the 8-member ring having a window size of at least 2.5 Angstroms×at least 3.6 Angstroms and at least one Brønsted acid site and the zeolite having a silica:X2O3 ratio of at least 5, wherein X is selected from aluminum, boron, iron, gallium and mixtures thereof.

摘要翻译： 包含低级脂族羧酸的低级烷基酯的产物是通过包括在基本上无水条件下使低级烷基醚与一氧化碳在具有8元环通道的沸石催化剂存在下反应的方法制得的，所述沸石催化剂与 通道由大于或等于8个构件的环限定，8元环的窗口尺寸至少为2.5埃至少为3.6埃和至少一个布朗斯台德酸位点，并且沸石具有二氧化硅：X 2 至少5，其中X选自铝，硼，铁，镓及其混合物。

公开(公告)号：US20060252959A1

公开(公告)日：2006-11-09

申请号：US11123581

申请日：2005-05-05

申请人： Patricia Cheung ,  Enrique Iglesia ,  John Sunley

发明人： Patricia Cheung ,  Enrique Iglesia ,  John Sunley

IPC分类号： C07C67/36

CPC分类号： C07C51/09 ,  C07C67/37 ,  C07C53/08 ,  C07C69/14

摘要： A product comprising a lower alkyl ester of a lower aliphatic carboxylic acid is produced by a process comprising reacting a lower alkyl ether with carbon monoxide in the presence of a catalyst comprising mordenite and/or ferrierite, under substantially anhydrous conditions. More specifically, methyl acetate is selectively produced by reaction of dimethyl ether with carbon monoxide in the presence of a catalyst comprising mordenite or ferrierite, under substantially anhydrous conditions.

摘要翻译： 包含低级脂族羧酸的低级烷基酯的产物是通过包括在基本上无水条件下在包含丝光沸石和/或镁碱沸石的催化剂存在下使低级烷基醚与一氧化碳反应的方法制备的。 更具体地说，在基本上无水条件下，在包含丝光沸石或镁碱沸石的催化剂的存在下，通过二甲醚与一氧化碳反应选择性地生产乙酸甲酯。