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    Aerosolization apparatus with feedback mechanism
    1.
    发明申请
    Aerosolization apparatus with feedback mechanism 有权
    具有反馈机制的气溶胶装置

    公开(公告)号：US20050051166A1

    公开(公告)日：2005-03-10

    申请号：US10704160

    申请日：2003-11-07

    申请人： Mark Glusker ,  Jeff Wood ,  John Burr

    发明人： Mark Glusker ,  Jeff Wood ,  John Burr

    IPC分类号： A61M15/00 ,  A61M16/00

    CPC分类号： A61M15/0028 ,  A61M15/0041 ,  A61M2202/064 ,  A61M2205/582

    摘要： An aerosolization apparatus comprises a housing defining a chamber having an air inlet and an air outlet, wherein the chamber is sized to receive a capsule containing a pharmaceutical formulation. A puncturing member is moveable within the chamber to contact the capsule and to provide an opening in the capsule, and a feedback mechanism provides an indication, such as a tactile indication, to a user when the puncturing member has been moved to a position where it provides the opening into the capsule. When air flows through the inlet, the pharmaceutical formulation is aerosolized and the aerosolized pharmaceutical formulation is delivered through the outlet.

    摘要翻译： 雾化装置包括限定具有空气入口和空气出口的室的壳体，其中所述室的尺寸设置成接收含有药物制剂的胶囊。 穿刺构件可在腔室内移动以接触胶囊并且在胶囊中提供开口，并且当穿刺构件已经移动到其位置时，反馈机构向使用者提供诸如触觉指示的指示 提供进入胶囊的开口。 当空气流过入口时，药物制剂被雾化并且雾化的药物制剂通过出口输送。

    BLISTER TRACK INHALER DEVICE HAVING A SEPARATE END PATH AND METHODS OF USE THEREOF
    2.
    发明申请
    BLISTER TRACK INHALER DEVICE HAVING A SEPARATE END PATH AND METHODS OF USE THEREOF 审中-公开
    具有独立终点路径的吸烟器吸入装置及其使用方法

    公开(公告)号：US20150090262A1

    公开(公告)日：2015-04-02

    申请号：US14495928

    申请日：2014-09-25

    申请人： Mark Glusker ,  Victoria Quitugua

    发明人： Mark Glusker ,  Victoria Quitugua

    IPC分类号： A61M15/00

    CPC分类号： A61M15/0051 ,  A61M15/0025 ,  A61M15/0026 ,  A61M15/0036 ,  A61M15/0041 ,  A61M15/0055 ,  A61M15/0068 ,  A61M2202/064 ,  A61M2205/58

    摘要： Embodiments of an inhaler device include a housing, a withdrawing assembly disposed within the housing for facilitating withdrawal of medicament from a target blister of a blister strip, the withdrawing assembly including an opening element adapted for opening the target blister of the blister strip while the target blister is positioned in the withdrawing assembly, and a dispensing element adapted for directing the withdrawn medicament toward the exterior of the inhaler device. A blister track is disposed within the housing for guiding each blister of the blister strip to the withdrawing assembly in succession, an advancing mechanism for advancing the blister strip by a predetermined distance each time the advancing mechanism is engaged, and an engaging element for engaging the advancing mechanism to advance the blister strip. The blister track includes a primary coil structure, a secondary coil structure, and a tertiary coil structure.

    摘要翻译： 吸入器装置的实施例包括壳体，设置在壳体内的抽出组件，用于促使药物从泡罩条的目标气泡抽出，该抽出组件包括适于打开泡罩条的目标气泡的开口元件，而目标 泡罩定位在抽出组件中，并且分配元件适于将抽出的药物引向吸入器装置的外部。 泡罩轨道设置在壳体内，用于将泡罩条的每个泡罩连续地引导到抽出组件，用于每次前进机构接合时将泡罩条推进预定距离的前进机构，以及用于接合 推进气泡条的前进机制。 泡罩轨道包括初级线圈结构，次级线圈结构和三级线圈结构。

    Blister track inhaler device having a separate end path and methods of use thereof
    4.
    发明授权
    Blister track inhaler device having a separate end path and methods of use thereof 有权

    公开(公告)号：US10258752B2

    公开(公告)日：2019-04-16

    申请号：US14495928

    申请日：2014-09-25

    申请人： Mark Glusker ,  Victoria Quitugua

    发明人： Mark Glusker ,  Victoria Quitugua

    IPC分类号： A61M15/00

    摘要： Embodiments of an inhaler device include a housing, a withdrawing assembly disposed within the housing for facilitating withdrawal of medicament from a target blister of a blister strip, the withdrawing assembly including an opening element adapted for opening the target blister of the blister strip while the target blister is positioned in the withdrawing assembly, and a dispensing element adapted for directing the withdrawn medicament toward the exterior of the inhaler device. A blister track is disposed within the housing for guiding each blister of the blister strip to the withdrawing assembly in succession, an advancing mechanism for advancing the blister strip by a predetermined distance each time the advancing mechanism is engaged, and an engaging element for engaging the advancing mechanism to advance the blister strip. The blister track includes a primary coil structure, a secondary coil structure, and a tertiary coil structure.

    Aerosolization apparatus with capsule puncture alignment guide
    6.
    发明申请
    Aerosolization apparatus with capsule puncture alignment guide 审中-公开
    胶囊穿刺对准导管的气雾化装置

    公开(公告)号：US20050000518A1

    公开(公告)日：2005-01-06

    申请号：US10821624

    申请日：2004-04-09

    申请人： Michael Dunkley ,  Jon Tuckwell ,  Edward Vernon-Harcourt ,  Mark Glusker ,  Steve Paboojian

    发明人： Michael Dunkley ,  Jon Tuckwell ,  Edward Vernon-Harcourt ,  Mark Glusker ,  Steve Paboojian

    IPC分类号： A61M15/00

    CPC分类号： A61M15/0028 ,  A61M15/0033 ,  A61M2202/064

    摘要： An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule. The alignment guide allows for more consistent puncturing of the capsule and a longer lifetime of the apparatus.

    摘要翻译： 雾化装置包括限定具有一个或多个空气入口的室的壳体。 该腔室的大小适于接收含有可雾化药物制剂的胶囊。 雾化装置还包括在壳体内的穿刺机构。 穿刺机构包括对准引导件和穿刺构件，其中对齐引导件包括适于在穿刺构件前进到胶囊中以接触胶囊的表面以在胶囊中形成开口。 表面的至少一部分相对于胶囊的纵向轴线倾斜。 或者或另外，表面可以包括一个或多个突起。 端部与壳体相关联。 端部的尺寸和形状被容纳在使用者的嘴或鼻中，使得使用者可以通过端部部分吸入，以吸入通过在胶囊中形成的开口离开胶囊的雾化药物制剂。 对准引导件允许胶囊的更一致的穿刺和装置的更长的使用寿命。

    Aerosolization apparatus with capsule puncture alignment guide
    8.
    发明授权
    Aerosolization apparatus with capsule puncture alignment guide 有权

    公开(公告)号：US10207066B2

    公开(公告)日：2019-02-19

    申请号：US10821624

    申请日：2004-04-09

    申请人： Michael John Dunkley ,  Jon David Tuckwell ,  Edward William Vernon-Harcourt ,  Mark Glusker ,  Steve Paboojian

    发明人： Michael John Dunkley ,  Jon David Tuckwell ,  Edward William Vernon-Harcourt ,  Mark Glusker ,  Steve Paboojian

    IPC分类号： A61M15/00

    摘要： An aerosolization apparatus comprises a housing defining a chamber having one or more air inlets. The chamber is sized to receive a capsule which contains an aerosolizable pharmaceutical formulation. The aerosolization apparatus further comprises a puncturing mechanism within the housing. The puncturing mechanism comprises an alignment guide and a puncture member, wherein the alignment guide comprises a surface adapted to contact the capsule while the puncture member is advanced into the capsule to create an opening in the capsule. At least a portion of the surface is sloped relative to the longitudinal axis of the capsule. Alternatively or additionally, the surface may comprise one or more protrusions. An end section is associated with the housing. The end section is sized and shaped to be received in a user's mouth or nose so that the user may inhale through the end section to inhale aerosolized pharmaceutical formulation that has exited the capsule through the opening created in the capsule. The alignment guide allows for more consistent puncturing of the capsule and a longer lifetime of the apparatus.