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公开(公告)号：US5904658A
公开(公告)日：1999-05-18
申请号：US916277
申请日：1997-08-22
申请人： Mark Q. Niederauer , Robert P. Wilkes , George M. Niederauer , Sabine Cristante , Steven F. Cline , Robert A. Tynmann
发明人： Mark Q. Niederauer , Robert P. Wilkes , George M. Niederauer , Sabine Cristante , Steven F. Cline , Robert A. Tynmann
IPC分类号： G01N3/48 , A61B5/103 , G01N3/40 , G01N3/42 , G01N33/483
CPC分类号： A61B5/4514 , A61B5/0053 , A61B5/103 , A61B5/442 , G01N3/42 , G01N33/4833 , A61B2560/0252 , A61B2560/0285 , A61B2562/0261 , A61B5/4528
摘要： A handheld materials testing device is provided for measuring compressive properties of a material, preferably articular cartilage in vivo. The device is computer-controlled and provides a readout indicative of the desired compressive property, which in the case of bodily tissue, may be indicative of the state of health of the tissue. The device does not require precise perpendicular alignment and is preferably capable of compensating for force applied by the user against the tissue.
摘要翻译： 提供了用于测量材料的压缩性能的手持式材料测试装置，优选在体内的关节软骨。 该装置是计算机控制的并且提供指示期望的压缩性质的读数，其在身体组织的情况下可以指示组织的健康状态。 该装置不需要精确的垂直对准，并且优选地能够补偿使用者施加在组织上的力。
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公开(公告)号：US5863297A
公开(公告)日：1999-01-26
申请号：US727204
申请日：1996-10-08
IPC分类号： A61F2/02 , A61F2/28 , A61F2/30 , A61F2/38 , A61F2/44 , A61L27/18 , A61L27/50 , A61L27/56 , A61L27/58 , A61L31/06 , A61L31/14
CPC分类号： A61L31/148 , A61F2/28 , A61F2/30756 , A61L27/18 , A61L27/50 , A61L27/56 , A61L27/58 , A61L31/06 , A61L31/14 , A61L31/146 , A61F2/3859 , A61F2/4455 , A61F2002/2807 , A61F2002/2835 , A61F2002/2878 , A61F2002/30062 , A61F2002/30677 , A61F2002/30766 , A61F2210/0004 , Y10S623/901 , Y10S623/902 , Y10S623/908
摘要： This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. When manufactured to have an aspect ratio greater than about 3, the implants can be further hand-shaped to fit the defect into which they are placed and the desired shape for the regrown tissue.
摘要翻译： 本发明提供了模塑的可生物降解的多孔聚合物植入材料，其具有贯穿整个材料的孔径分布，其基本均匀。 这些材料可以模制成任何所需尺寸和形状的植入物，而不损失孔径分布的均匀性。 植入物可用作生物降解支架，用于组织缺损愈合中的细胞生长。 当制造成具有大于约3的纵横比时，植入物可以进一步手形以适应它们所放置的缺陷和用于再生长组织的期望形状。
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3.发明授权Method of making biodegradable implant material and products made therefrom 失效制造生物可降解植入材料的方法及由其制成的产品公开(公告)号：US06203573B1
公开(公告)日：2001-03-20
申请号：US09234761
申请日：1999-01-21
IPC分类号： A61F228
CPC分类号： A61L31/148 , A61F2/28 , A61F2/30756 , A61F2/3859 , A61F2/4455 , A61F2002/2807 , A61F2002/2835 , A61F2002/2878 , A61F2002/30062 , A61F2002/30677 , A61F2002/30766 , A61F2210/0004 , A61L27/18 , A61L27/50 , A61L27/56 , A61L27/58 , A61L31/06 , A61L31/14 , A61L31/146 , Y10S623/901 , Y10S623/902 , Y10S623/908 , A61L27/54 , C08L67/04 , A61L31/16
摘要： This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. When manufactured to have an aspect ratio greater than about 3, the implants can be further hand-shaped to fit the defect into which they are placed and the desired shape for the regrown tissue.
摘要翻译： 本发明提供了模塑的可生物降解的多孔聚合物植入材料，其具有贯穿整个材料的孔径分布，其基本均匀。 这些材料可以模制成任何所需尺寸和形状的植入物，而不损失孔径分布的均匀性。 植入物可用作生物降解支架，用于组织缺损愈合中的细胞生长。 当制造成具有大于约3的纵横比时，植入物可以进一步手形以适应它们所放置的缺陷和用于再生长组织的期望形状。
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公开(公告)号：US6156068A
公开(公告)日：2000-12-05
申请号：US235045
申请日：1999-01-21
IPC分类号： A61F2/02 , A61F2/28 , A61F2/30 , A61F2/38 , A61F2/44 , A61L27/18 , A61L27/50 , A61L27/56 , A61L27/58 , A61L31/06 , A61L31/14 , A61B17/56 , A61F2/36
CPC分类号： A61L31/148 , A61F2/28 , A61F2/30756 , A61L27/18 , A61L27/50 , A61L27/56 , A61L27/58 , A61L31/06 , A61L31/14 , A61L31/146 , A61F2/3859 , A61F2/4455 , A61F2002/2807 , A61F2002/2835 , A61F2002/2878 , A61F2002/30062 , A61F2002/30677 , A61F2002/30766 , A61F2210/0004 , Y10S623/901 , Y10S623/902 , Y10S623/908
摘要： This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. When manufactured to have an aspect ratio greater than about 3, the implants can be further hand-shaped to fit the defect into which they are placed and the desired shape for the regrown tissue.
摘要翻译： 本发明提供了模塑的可生物降解的多孔聚合物植入材料，其具有贯穿整个材料的孔径分布，其基本均匀。 这些材料可以模制成任何所需尺寸和形状的植入物，而不损失孔径分布的均匀性。 植入物可用作生物降解支架，用于组织缺损愈合中的细胞生长。 当制造成具有大于约3的纵横比时，植入物可以进一步手形以适应放置在其中的缺陷和用于再生长组织的期望形状。
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公开(公告)号：US5716413A
公开(公告)日：1998-02-10
申请号：US540788
申请日：1995-10-11
IPC分类号： A61F2/02 , A61F2/28 , A61F2/30 , A61F2/38 , A61F2/44 , A61L27/18 , A61L27/50 , A61L27/56 , A61L27/58 , A61L31/06 , A61L31/14
CPC分类号： A61L31/148 , A61F2/28 , A61F2/30756 , A61L27/18 , A61L27/50 , A61L27/56 , A61L27/58 , A61L31/06 , A61L31/14 , A61L31/146 , A61F2/3859 , A61F2/4455 , A61F2002/2807 , A61F2002/2835 , A61F2002/2878 , A61F2002/30062 , A61F2002/30677 , A61F2002/30766 , A61F2210/0004 , Y10S623/901 , Y10S623/902 , Y10S623/908
摘要： This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. When manufactured to have an aspect ratio greater than about 3, the implants can be further hand-shaped to fit the defect into which they are placed and the desired shape for the regrown tissue.
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