公开(公告)号：US20050053053A1

公开(公告)日：2005-03-10

申请号：US10658053

申请日：2003-09-09

申请人： Mark Smith ,  Shiping Li ,  James Pasco-Anderson

发明人： Mark Smith ,  Shiping Li ,  James Pasco-Anderson

IPC分类号： H04L12/64 ,  H04L12/66

CPC分类号： H04L12/6418

摘要： A gateway apparatus includes multiple network server cards which are synchronized with each other to allow time slot switching of synchronous data across an asynchronous medium between source and destination server cards. The gateway includes synchronization logic and a data adaptation layer which implements a protocol for formatting of synchronous serial data. The data undergoes serial to parallel conversion and is formed into per time slot subpackets which are further packetized along with context and synchronization data. The packet is transmitted through an asynchronous switch after which the packet is disassembled into its constituent subpackets and queued into play-out buffers according to each subpackets' associated context and synchronization data. The apparatus allows synchronous data to be switched from a source time slot to a destination time slot across the asynchronous switch with a known, fixed delay. The gateway apparatus requires only a single asynchronous switch to transmit data between and among both the synchronous and asynchronous domains.

摘要翻译： 网关装置包括彼此同步的多个网络服务器卡，以允许在源服务器卡和目的地服务器卡之间的异步介质上的同步数据的时隙切换。 网关包括同步逻辑和实现用于格式化同步串行数据的协议的数据适配层。 数据经历串行到并行转换，并且形成为每个时隙子分组，其随着上下文和同步数据进一步分组化。 分组通过异步交换机传输，之后分组被拆分成其组成子分组，并根据每个子分组的相关上下文和同步数据排队到播出缓冲器中。 该装置允许同步数据以已知的固定延迟从异常交换机的源时隙切换到目的时隙。 网关设备只需要一个异步交换机来在同步和异步域之间进行数据传输。

公开(公告)号：US07586925B2

公开(公告)日：2009-09-08

申请号：US10658352

申请日：2003-09-09

申请人： Mark Smith ,  Shiping Li ,  James Pasco-Anderson

发明人： Mark Smith ,  Shiping Li ,  James Pasco-Anderson

IPC分类号： H04L12/28

CPC分类号： H04J3/0685

摘要： A gateway apparatus includes multiple network server cards which are synchronized with each other to allow time slot switching of synchronous data across an asynchronous medium between source and destination server cards. The gateway includes synchronization logic and a data adaptation layer which implements a protocol for formatting of synchronous serial data. The data undergoes serial to parallel conversion and is formed into per time slot subpackets which are further packetized along with context and synchronization data. The packet is transmitted through an asynchronous switch after which the packet is disassembled into its constituent subpackets and queued into play-out buffers according to each subpackets' associated context and synchronization data. The apparatus allows synchronous data to be switched from a source time slot to a destination time slot across the asynchronous switch with a known, fixed delay. The gateway apparatus requires only a single asynchronous switch to transmit data between and among both the synchronous and asynchronous domains.

摘要翻译： 网关装置包括彼此同步的多个网络服务器卡，以允许在源服务器卡和目的地服务器卡之间的异步介质上的同步数据的时隙切换。 网关包括同步逻辑和实现用于格式化同步串行数据的协议的数据适配层。 数据经历串行到并行转换，并且形成为每个时隙子分组，其随着上下文和同步数据进一步分组化。 分组通过异步交换机传输，之后分组被拆分成其组成子分组，并根据每个子分组的相关上下文和同步数据排队到播出缓冲器中。 该装置允许同步数据以已知的固定延迟从异常交换机的源时隙切换到目的时隙。 网关设备只需要一个异步交换机来在同步和异步域之间进行数据传输。

公开(公告)号：US20050053028A1

公开(公告)日：2005-03-10

申请号：US10658352

申请日：2003-09-09

申请人： Mark Smith ,  Shiping Li ,  James Pasco-Anderson

发明人： Mark Smith ,  Shiping Li ,  James Pasco-Anderson

IPC分类号： H04B7/212 ,  H04J3/06

CPC分类号： H04J3/0685

摘要： A gateway apparatus includes multiple network server cards which are synchronized with each other to allow time slot switching of synchronous data across an asynchronous medium between source and destination server cards. The gateway includes synchronization logic and a data adaptation layer which implements a protocol for formatting of synchronous serial data. The data undergoes serial to parallel conversion and is formed into per time slot subpackets which are further packetized along with context and synchronization data. The packet is transmitted through an asynchronous switch after which the packet is disassembled into its constituent subpackets and queued into play-out buffers according to each subpackets' associated context and synchronization data. The apparatus allows synchronous data to be switched from a source time slot to a destination time slot across the asynchronous switch with a known, fixed delay. The gateway apparatus requires only a single asynchronous switch to transmit data between and among both the synchronous and asynchronous domains.

摘要翻译： 网关装置包括彼此同步的多个网络服务器卡，以允许在源服务器卡和目的地服务器卡之间的异步介质上的同步数据的时隙切换。 网关包括同步逻辑和实现用于格式化同步串行数据的协议的数据适配层。 数据经历串行到并行转换，并且形成为每个时隙子分组，其随着上下文和同步数据进一步分组化。 分组通过异步交换机传输，之后分组被拆分成其组成子分组，并根据每个子分组的相关上下文和同步数据排队到播出缓冲器中。 该装置允许同步数据以已知的固定延迟从异常交换机的源时隙切换到目的时隙。 网关设备只需要一个异步交换机来在同步和异步域之间进行数据传输。

公开(公告)号：US11951746B2

公开(公告)日：2024-04-09

申请号：US17429748

申请日：2020-03-06

申请人： James R. Pryde ,  Mark Smith ,  Robert Hargreaves

发明人： James R. Pryde ,  Mark Smith ,  Robert Hargreaves

IPC分类号： B41J2/175 ,  G03G15/08

CPC分类号： B41J2/17523 ,  G03G15/0877

摘要： A device (1) for controlling user access to at least one container (4) for dispensing printing material housed by a printing apparatus (5), the device (1) comprising an openable and closable barrier (2) corresponding to the container (4) and a lock for locking the barrier (2) in a closed position. The lock is overlapped by at least a portion of the barrier (2) both when the barrier (2) is in the closed position and when the barrier (2) is in an open position.

公开(公告)号：US20170206608A1

公开(公告)日：2017-07-20

申请号：US15403374

申请日：2017-01-11

申请人： Mark Smith

发明人： Mark Smith

IPC分类号： G06Q40/08 ,  G06Q40/00 ,  G06Q40/06

CPC分类号： G06Q40/08 ,  G06Q40/06 ,  G06Q40/10

摘要： A Horizontally-Linked Reinsurance Network (HLRN) formed of a plurality of small insurance companies (as defined by applicable law, e.g. U.S.C. §831(b)) that is established and managed by a network administrator presents a new approach to harnessing the benefits of small insurance companies while mitigating the drawbacks of small insurance companies. This system uses a rules-based approach and algorithm to select, allocate, optimize and manage the individual risk portfolio of independent small insurance companies so as to preserve their status as a small insurance company while diversifying risk. Further, network administrator will perform the management functions if the HLRN. This allows investors or persons who would not otherwise own an insurance company to invest in a new asset class which by its nature demonstrates a non-correlation to traditional investment markets and carries both unique return and tax properties.

公开(公告)号：USD729041S1

公开(公告)日：2015-05-12

申请号：US29433547

申请日：2012-10-01

申请人： Mark Smith

设计人： Mark Smith

公开(公告)号：US20150038409A1

公开(公告)日：2015-02-05

申请号：US14097818

申请日：2013-12-05

申请人： Nikolaos Tezapsidis ,  Steven Greco ,  Mark Smith

发明人： Nikolaos Tezapsidis ,  Steven Greco ,  Mark Smith

IPC分类号： A61K38/22 ,  A61K31/7056

CPC分类号： A61K38/22 ,  A61K31/7056 ,  A61K38/2264 ,  A61K45/06 ,  C12Q1/485 ,  G01N33/5058 ,  G01N2800/2821 ,  G01N2800/2828 ,  A61K2300/00

摘要： The present disclosure provides compositions containing a leptin product and methods of clinical therapy and diagnostic methods for progressive cognitive disorders. According to one aspect, the described invention provides a method for treating a progressive cognitive disorder. According to another aspect, the described invention provides a method for improving resilience of cognitive function in a subject in need thereof. According to another aspect, the described invention provides a method for identifying an effective therapeutic agent for treating a progressive cognitive dysfunction disease or disorder that results from at least one of accumulation of Aβ, hyperphosphorylation of tau, or accumulation of neurofibrillary tangles.

摘要翻译： 本公开提供了含有瘦素产物的组合物和用于进行性认知障碍的临床治疗和诊断方法的方法。 根据一个方面，所述发明提供了治疗进行性认知障碍的方法。 根据另一方面，本发明提供了一种用于提高有需要的受试者的认知功能的弹性的方法。 根据另一方面，所述发明提供了鉴定用于治疗进行性认知功能障碍疾病或病症的有效治疗剂的方法，所述有效治疗剂由A和BGR的累积，tau的高度磷酸化或神经原纤维缠结的积累中的至少一种引起。

公开(公告)号：US08795194B2

公开(公告)日：2014-08-05

申请号：US12058910

申请日：2008-03-31

申请人： Mark Howard ,  Mark Smith

发明人： Mark Howard ,  Mark Smith

IPC分类号： A61B10/02 ,  A61M1/00 ,  B01D25/00

CPC分类号： C12N5/0653 ,  A61B10/025 ,  A61B10/0283 ,  A61B17/1635 ,  A61B17/32002 ,  A61B17/3205 ,  A61B2017/00969 ,  A61B2217/005 ,  A61M1/00 ,  A61M1/0056 ,  A61M2202/0014 ,  A61M2202/08

摘要： The present disclosure relates to a tissue collection apparatus. The tissue collection apparatus comprises a housing defining an inlet and an outlet, a first filter disposed within the housing, a second filter disposed within the housing, the second filter configured to isolate tissue particles of a desired size that pass through the first filter under the application of an aspiration force applied through the housing. A method of harvesting tissue is also disclosed.

摘要翻译： 本公开涉及一种组织收集装置。 所述组织收集装置包括限定入口和出口的壳体，设置在所述壳体内的第一过滤器，设置在所述壳体内的第二过滤器，所述第二过滤器被配置为将通过所述第一过滤器的所需尺寸的组织颗粒隔开， 施加通过壳体施加的抽吸力。 还公开了收获组织的方法。

公开(公告)号：US08642543B2

公开(公告)日：2014-02-04

申请号：US12470427

申请日：2009-05-21

申请人： Nikolaos Tezapsidis ,  Steven Greco ,  Mark Smith

发明人： Nikolaos Tezapsidis ,  Steven Greco ,  Mark Smith

IPC分类号： A61K38/22

CPC分类号： A61K38/2264 ,  A61K38/22 ,  A61K38/28 ,  A61K45/06 ,  A61K2300/00

摘要： The described invention provides methods for treating or preventing progression of a progressive cognitive disease, disorder or condition, and methods for improving resilience of cognitive function in a subject in need thereof.

摘要翻译： 所述发明提供了用于治疗或预防进行性认知疾病，病症或病症进展的方法，以及用于在有需要的受试者中提高认知功能的弹性的方法。

公开(公告)号：US08312562B2

公开(公告)日：2012-11-20

申请号：US12715263

申请日：2010-03-01

申请人： Gary Hammons ,  Roger W. Kramer ,  Charles Marks ,  Kevin Porter ,  Robert Bogard ,  Traci Skahill ,  Mark Smith

发明人： Gary Hammons ,  Roger W. Kramer ,  Charles Marks ,  Kevin Porter ,  Robert Bogard ,  Traci Skahill ,  Mark Smith

IPC分类号： A41D19/00

CPC分类号： A41D31/005 ,  A41D19/01523 ,  A43B13/187 ,  A43B13/189 ,  A47C7/021 ,  B60N2/522 ,  B60N2/525 ,  B60N2/70 ,  F16F3/093 ,  F16F2230/36

摘要： An impact and/or vibration absorbent material and protective articles making use of said material. An impact and/or vibration absorbent material of the present invention has at least two material layers. The individual layers of the impact and/or vibration absorbent material may be of different materials, or of the same material with the composition of the material of one layer adjusted to be of dissimilar hardness to an adjacent layer. Each material layer preferably contains a number of holes. The holes in one layer are located and arranged to be offset from the holes in an adjacent layer. The combination of material properties and the inclusion and arrangement of holes renders such a material highly impact and/or vibration absorbent. Through use of a protective article of the present invention, the effects of impact and/or vibration forces on a user of the protective article can be minimized.

摘要翻译： 使用所述材料的冲击和/或振动吸收材料和保护制品。 本发明的冲击和/或振动吸收材料具有至少两个材料层。 冲击和/或振动吸收材料的各个层可以是不同的材料，或者具有相同材料的材料，其中一层材料的组成被调整为与相邻层具有不同的硬度。 每个材料层优选地包含许多孔。 一层中的孔位于并布置成偏离相邻层中的孔。 材料性质的组合和孔的包含和排列使得这种材料具有高度冲击和/或吸振性。 通过使用本发明的保护制品，能够使冲击力和/或振动力对保护用品的使用者的影响最小化。