摘要:
The present invention provides an altered antibody molecule wherein a residue in a surface pocket on the molecule has been changed to a cysteine residue to introduce a thiol group in the surface pocket and a process for its production by recombinant DNA technology.
摘要:
Human interferons containing novel cysteine substitutions and disulfide bonds are disclosed. The amino acid sequence of a first interferon is combined with the cysteine and/or disulfide pattern of a second interferon resulting in a molecule with hybrid properties.