2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive
function
    10.
    发明授权
    2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function 失效
    2 - ((硝基)苯氧基甲基)杂环化合物,增强认知功能

    公开(公告)号:US5472958A

    公开(公告)日:1995-12-05

    申请号:US297454

    申请日:1994-08-29

    IPC分类号: A61K31/40 A61K31/33

    CPC分类号: A61K31/40

    摘要: Selective and potent cholinergic ligands selective for neuronal nicotinic cholinergic channel receptors, which ligands have the formula: ##STR1## as well as pharmaceutically-acceptable salts or prodrugs thereof, which are useful in the treatment of dementias, attentional hyperactivity disorder, or substance abuse withdrawal characterized by decreased cholinergic function, one of which is also an analgesic agent, and one of which is an agent useful for treating anxiety associated with cognitive impairment.

    摘要翻译: 对神经元烟碱性胆碱能通道受体有选择性和有效的胆碱能配体,其配体具有以下分子式:及其药学上可接受的盐或前药,其可用于治疗痴呆,注意性多动症或药物滥用戒断 其特征在于胆碱能功能降低,其中之一也是止痛剂,其中之一是可用于治疗与认知障碍相关的焦虑的药剂。