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    Method of increasing fruit size in a plant
    1.
    发明授权
    Method of increasing fruit size in a plant 失效
    增加植物果实大小的方法

    公开(公告)号：US06229068B1

    公开(公告)日：2001-05-08

    申请号：US09105652

    申请日：1998-06-26

    申请人： Martin F. Yanofsky ,  Robert Martienssen ,  Cristina Ferrandiz ,  Qing Gu

    发明人： Martin F. Yanofsky ,  Robert Martienssen ,  Cristina Ferrandiz ,  Qing Gu

    IPC分类号： C12N1582

    CPC分类号： C12N15/8222 ,  C07K14/415 ,  C12N15/8234 ,  C12N15/8261 ,  C12N15/8266 ,  Y02A40/146

    摘要： The present invention provides a non-naturally occurring seed plant that is characterized by producing seeds of increased size due to ectopic expression of a nucleic acid molecule encoding an AGL8-related gene product. The AGL8-related gene product can have, for example, substantially the amino acid sequence of an AGL8 ortholog such as Arabidopsis AGL8 (SEQ ID NO:2). The present invention further provides a non-naturally occurring seed plant that is characterized by producing fruit of increased size due to ectopic expression of a nucleic acid molecule encoding an AGL8-family gene product. The AGL8-family gene product can have substantially the amino acid sequence of an AGL8 ortholog, for example, the amino acid sequence of Arabidopsis AGL8 (SEQ ID NO:2). Related methods and kits also are provided.

    摘要翻译： 本发明提供一种非天然存在的种子植物，其特征在于由于编码AGL8相关基因产物的核酸分子的异位表达而产生大小增加的种子。 AGL8相关基因产物可以具有例如基本上AGL8直系同源物的氨基酸序列，例如拟南芥AGL8（SEQ ID NO：2）。 本发明还提供一种非天然存在的种子植物，其特征在于产生由于编码AGL8家族基因产物的核酸分子的异位表达而增加的大小的果实。 AGL8家族基因产物可以具有基本上AGL8直系同源物的氨基酸序列，例如拟南芥AGL8（SEQ ID NO：2）的氨基酸序列。 还提供了相关方法和试剂盒。

    Method of decreasing seed size in a plant
    2.
    发明授权
    Method of decreasing seed size in a plant 有权
    减少植物种子大小的方法

    公开(公告)号：US06541683B1

    公开(公告)日：2003-04-01

    申请号：US09708584

    申请日：2000-11-07

    申请人： Martin F. Yanofsky ,  Robert Martienssen ,  Cristina Ferrandiz ,  Qing Gu

    发明人： Martin F. Yanofsky ,  Robert Martienssen ,  Cristina Ferrandiz ,  Qing Gu

    IPC分类号： C12N1582

    CPC分类号： C12N15/8222 ,  C07K14/415 ,  C12N15/8234 ,  C12N15/8261 ,  C12N15/8266 ,  Y02A40/146

    摘要： The present invention provides a non-naturally occurring seed plant that is characterized by producing seeds of increased size due to ectopic expression of a nucleic acid molecule encoding an AGL8-related gene product. The AGL8-related gene product can have, for example, substantially the amino acid sequence of an AGL8 ortholog such as Arabidopsis AGL8 (SEQ ID NO:2). The present invention further provides a non-naturally occurring seed plant that is characterized by producing fruit of increased size due to ectopic expression of a nucleic acid molecule encoding an AGL8-family gene product. The AGL8-family gene product can have substantially the amino acid sequence of an AGL8 ortholog, for example, the amino acid sequence of Arabidopsis AGL8 (SEQ ID NO:2). Related methods and kits also are provided.

    摘要翻译： 本发明提供一种非天然存在的种子植物，其特征在于由于编码AGL8相关基因产物的核酸分子的异位表达而产生大小增加的种子。 AGL8相关基因产物可以具有例如基本上AGL8直系同源物的氨基酸序列，例如拟南芥AGL8（SEQ ID NO：2）。 本发明还提供一种非天然存在的种子植物，其特征在于产生由于编码AGL8家族基因产物的核酸分子的异位表达而增加的大小的果实。 AGL8家族基因产物可以具有基本上AGL8直系同源物的氨基酸序列，例如拟南芥AGL8（SEQ ID NO：2）的氨基酸序列。 还提供了相关方法和试剂盒。

    RNAI-based modification of heterochromatin
    3.
    发明申请
    RNAI-based modification of heterochromatin 审中-公开
    基于RNAI的异染色质修饰

    公开(公告)号：US20050112763A1

    公开(公告)日：2005-05-26

    申请号：US10923268

    申请日：2004-08-20

    申请人： Shivinder Grewal ,  Thomas Volpe ,  Ira Hall ,  Catherine Kidner ,  Robert Martienssen

    发明人： Shivinder Grewal ,  Thomas Volpe ,  Ira Hall ,  Catherine Kidner ,  Robert Martienssen

    IPC分类号： A61K48/00 ,  C12N20060101 ,  C12N15/113 ,  C12N15/63

    CPC分类号： C12N15/113 ,  C12N15/63 ,  C12N2310/14

    摘要： Methods of regulating the formation of heterochromatin at a target locus within the genome of a cell and methods of regulating the modification of a histone protein assumed on the DNA of a target locus within the genome of a cell are provided. In particular, the invention provides methods to regulate the structure of the genome of a cell, where the structure is regulated by modulating heterochromatin formation, heterochromatin architecture, histone methylation, and/or DNA methylation, by exposing the cell to an RNAi probe complementary to a target locus so as to activate the RNAi machinery to modify the genomic structure of the target locus and adjacent segments of the genome.

    摘要翻译： 提供了调节细胞基因组内目标基因座上异染色质形成的方法和调节细胞基因组内基因组DNA上假定的组蛋白蛋白质修饰的方法。 特别地，本发明提供了调节细胞基因组结构的方法，其中结构通过调节异染色质形成，异染色质结构，组蛋白甲基化和/或DNA甲基化来调节，通过将细胞暴露于互补的RNAi探针 靶基因座，以激活RNAi机制以修饰靶基因座和基因组相邻区段的基因组结构。