Method for the continuous production of tetra-substituted ureas
    10.
    发明授权
    Method for the continuous production of tetra-substituted ureas 失效
    连续生产四取代脲的方法

    公开(公告)号:US07053244B2

    公开(公告)日:2006-05-30

    申请号:US10520402

    申请日:2003-07-03

    IPC分类号: C07C273/18

    CPC分类号: C07C273/1809 C07C275/06

    摘要: The invention relates to a process for the preparation of tetrasubstituted ureas by reaction of the corresponding amines with phosgene in the presence of an aqueous inorganic base at a temperature in the range from 0 to 150° C., which comprises: feeding the corresponding amine, the phosgene and the aqueous inorganic base on average continuously to the reaction apparatus, forming a two-phase system in the reaction apparatus through the choice of the tetrasubstituted ureas to be prepared, through the mixing ratios of the substances and substance mixtures to be fed in, through the temperature during the reaction and, where appropriate, through the feed of an organic solvent which is not completely miscible with water, and discharging the reaction mixture on average continuously from the reaction apparatus.

    摘要翻译: 本发明涉及通过在无机碱水溶液存在下,在0至150℃的温度范围内使相应的胺与光气反应来制备四取代的脲的方法,该方法包括:将相应的胺, 光气和水无机碱平均连续向反应装置中,通过选择要制备的四取代脲形成反应装置中的两相体系,通过待进料的物质和物质混合物的混合比例 通过反应期间的温度,并且在适当的情况下,通过进料与水不完全混溶的有机溶剂,并从反应装置中连续排出反应混合物。