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公开(公告)号:US6034121A
公开(公告)日:2000-03-07
申请号:US51135
申请日:1998-04-01
申请人: Mary Josephine O'Mahony , Peter John West , Jacqueline Anne MacRitchie , Stephen David Lindell , Peter Millward
发明人: Mary Josephine O'Mahony , Peter John West , Jacqueline Anne MacRitchie , Stephen David Lindell , Peter Millward
IPC分类号: C07H17/07 , A01N43/16 , A01N43/40 , A01N43/54 , A01N43/653 , A01N43/78 , A01N43/80 , A01N43/84 , A01N43/90 , A01N55/00 , C07D311/12 , C07D311/18 , C07D311/22 , C07D311/54 , C07D311/56 , C07D405/04 , C07D405/12 , C07D407/12 , C07D413/04 , C07D417/12
CPC分类号: C07D311/18 , A01N43/16 , C07D311/22 , C07D311/54 , C07D311/56
摘要: Compounds of the formula ##STR1## where one of Z and Y is CO and the other is C--W--R.sup.2 and the dotted line indicates a double bond is present where necessary to meet valency requirements, W is O, S(O).sub.n, N(R.sup.3), N(R.sup.3)(R.sup.4), N(R.sup.3)O or ON(R.sup.3); R.sup.1 is hydrogen, or an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, phenyl or heterocyclyl group; R.sup.2, R.sup.3 and R.sup.4, which may be the same or different, are as defined above for R.sup.1, or are acyl, or R.sup.2 and R.sup.3 or R.sup.2 and R.sup.4 or R.sup.3 and R.sup.4 together with the nitrogen or oxygen to which they are attached form an optionally substituted ring which may contain other hetero atoms; each X, which may be the same as or different from any other X, is halogen, CN, NO.sub.2, SF.sub.5, B(OH).sub.2, triakylsilyl or a group E, OE or S(O).sub.n E where E is a group as defined hereinbefore for R.sup.2 or is optionally substituted amino; or two adjacent groups X together with the atoms to which they are attached form an optionally substituted carbocyclic or heterocyclic ring; n is 0, 1 or 2; and p is 0 to 4 have fungicidal activity. Many of the compounds are novel.
摘要翻译: W为O,S(O)n,N(R3)的化合物,其中Z和Y中的一个为CO且另一个为CW-R 2且虚线表示双键, ,N(R3)(R4),N(R3)O或ON(R3); R 1是氢或任选取代的烷基,烯基,炔基,环烷基,苯基或杂环基; R 2,R 3和R 4可以相同或不同,如对于R 1所定义,或是酰基,或R 2和R 3或R 2和R 4或R 3和R 4与它们所连接的氮或氧一起形成 可以含有其它杂原子的任选取代的环; 每个X可以与任何其它X相同或不同,是卤素,CN,NO 2,SF 5,B(OH)2,三烷基甲硅烷基或基团E,OE或S(O)nE,其中E是基团 对于R2定义或任选取代的氨基; 或两个相邻基团X与它们所连接的原子一起形成任选取代的碳环或杂环; n为0,1或2; p为0〜4具有杀菌活性。 许多化合物是新颖的。
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公开(公告)号:US06541630B1
公开(公告)日:2003-04-01
申请号:US10172891
申请日:2002-06-13
申请人: John Frederick Atherall , Thomas Lawley Hough , Stephen David Lindell , Mary Josephine O'Mahony , John Henry Parsons , Elizabeth Anne Saville-Stones
发明人: John Frederick Atherall , Thomas Lawley Hough , Stephen David Lindell , Mary Josephine O'Mahony , John Henry Parsons , Elizabeth Anne Saville-Stones
IPC分类号: C07D49504
CPC分类号: C07D495/04 , A01N43/90
摘要: The invention provides the use in combating fungi of compounds of general formula I wherein R1 is hydrogen, hydroxy, acyl, acyloxy, optionally substituted amino, Ra, Ra3Si, RaS or RaO, where Ra is optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl, optionally substituted aryl or optionally substituted heterocyclyl; Z is oxygen or sulfur; M is a thiophene ring; and R3 and R4, which may be the same or different, have the same meaning as Ra or can be optionally substituted amino, hydrogen, halogen, cyano, nitro or a group ORc or S(O)mRc, where Rc has the same meaning as Ra or is hydrogen or acyl and m is 0, 1 or 2; or R3 and R4 together with the atoms to which they are attached form an optionally substituted carbocyclic or heterocyclic ring; together with tautomers of compounds where R1 is hydrogen.
摘要翻译: 本发明提供了用于对抗通式I化合物的用途,其中R 1是氢,羟基,酰基,酰氧基,任选取代的氨基,R a,R 3 Si,RaS或RaO,其中R a是任选取代的烷基,任选取代的链烯基, 炔基,任选取代的环烷基,任选取代的环烯基,任选取代的芳基或任选取代的杂环基; Z是氧或硫; M是噻吩环; 和R 3和R 4可以相同或不同,具有与R a相同的含义或可以是任选取代的氨基,氢,卤素,氰基,硝基或基团OR c或S(O)m R c,其中R c具有相同的含义 为Ra或为氢或酰基,m为0,1或2; 或R 3和R 4与它们所连接的原子一起形成任选取代的碳环或杂环; 以及R1为氢的化合物的互变异构体。
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公开(公告)号:US06432964B1
公开(公告)日:2002-08-13
申请号:US09423135
申请日:1999-11-05
申请人: John Frederick Atherall , Thomas Lawley Hough , Stephen David Lindell , Mary Josephine O'Mahony , John Henry Parsons , Elizabeth Anne Saville-Stones
发明人: John Frederick Atherall , Thomas Lawley Hough , Stephen David Lindell , Mary Josephine O'Mahony , John Henry Parsons , Elizabeth Anne Saville-Stones
IPC分类号: A01N4390
CPC分类号: C07D495/04 , A01N43/90
摘要: The invention provides the use in combating fungi of compounds of general formula (I) wherein R1 is hydrogen, hydroxy, acyl, acyloxy, optionally substituted amino, Ra, Ra3Si, RaS or RaO, where Ra is optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl, optionally substituted aryl or optionally substituted heterocyclyl; R2 has the same meaning as Ra or can be hydrogen; Z is oxygen or sulfur, M is a thiophene ring, and R3 and R4, which may be the same or different, have the same meaning as Ra or can be optionally substituted amino, hydrogen, halogen, cyano, nitro or a group ORc or S(O)mRc, where Rc has the same meaning as Ra or is hydrogen or acyl and m is 0, 1 or 2; or R3 and R4 together with the atoms to which they are attached form an optionally substituted carbocyclic or heterocyclic ring; together with tautomers of compounds where R1 is hydrogen.
摘要翻译: 本发明提供了用于对抗通式(I)的化合物的用途,其中R 1是氢,羟基,酰基,酰氧基,任选取代的氨基,Ra,Ra 3 Si,RaS或RaO,其中R a是任选取代的烷基,任选取代的链烯基, 任选取代的炔基,任选取代的环烷基,任选取代的环烯基,任选取代的芳基或任选取代的杂环基; R2具有与Ra相同的含义,也可以是氢; Z是氧或硫,M是噻吩环,并且可以相同或不同的R 3和R 4具有与R a相同的含义或可以是任选取代的氨基,氢,卤素,氰基,硝基或基团OR c或 S(O)m R c,其中R c具有与R a相同的含义或氢或酰基,m为0,1或2; 或R 3和R 4与它们所连接的原子一起形成任选取代的碳环或杂环; 以及R1为氢的化合物的互变异构体。
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公开(公告)号:US5786165A
公开(公告)日:1998-07-28
申请号:US765880
申请日:1997-01-02
CPC分类号: C12Q1/34 , A01N61/00 , G01N2333/415 , G01N2333/978 , G01N2430/20 , G01N2500/00
摘要: Potential herbicides can be identified by testing compounds in an AMP deaminase inhibition assay. Also disclosed is the use as a herbicide of a compound which is an inhibitor of AMP deaminase in planta and causes elevated ATP levels in susceptible plants.
摘要翻译: PCT No.PCT / EP95 / 02423 Sec。 371日期1997年1月2日 102(e)日期1997年1月2日PCT Filed June 22,1995 PCT Pub。 出版物WO96 / 01326 日期1996年1月18日可以通过在AMP脱氨酶抑制测定中测试化合物来鉴定潜在除草剂。 还公开了作为植物中AMP脱氨酶抑制剂的化合物的除草剂的用途,并在易感植物中引起升高的ATP水平。
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