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1.发明授权
公开(公告)号：US4943564A
公开(公告)日：1990-07-24
申请号：US928226
申请日：1986-10-16
IPC分类号： A61K9/08 , A61K9/00 , A61K9/107 , A61K31/70 , A61K47/12 , A61K47/14 , A61K47/44 , A61P35/00 , C07H19/06 , C07H19/10
摘要： Pharmaceutical preparations for intraarterial administration use comprising highly fat soluble derivatives of 5-fluoro-2'-deoxyuridine having the antitumor activity and oleaginous bases, wherein the property of selectively migrating to the tumor tissue and the accumulating function of 5-fluoro-2'-deoxyuridine esters are remarkably improved.
摘要翻译： PCT No.PCT / JP86 / 00071 Sec。 371日期1986年10月16日第 102（e）日期1986年10月16日PCT提交1986年2月17日PCT公布。 出版物WO86 / 04816 1986年8月28日。用于动脉内给药用途的药物制剂，其包含具有抗肿瘤活性的5-氟-2'-脱氧尿苷的高脂溶性衍生物和油性碱，其中选择性迁移至肿瘤组织的性质和累积功能 5-氟-2'-脱氧尿苷酯显着改善。
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公开(公告)号：US07459482B2
公开(公告)日：2008-12-02
申请号：US11495709
申请日：2006-07-31
IPC分类号： A61K31/282
CPC分类号： A61K9/0019 , A61K9/08 , A61K9/10 , A61K31/282 , A61K47/14 , A61K47/24 , A61K47/44
摘要： Preparation of a lipophilic platinum complex being dissolved or suspended in an iodized poppyseed oil fatty acid ethyl ester is useful as an agent for treatment of cisplatin-resistant cancers.
摘要翻译： 溶解或悬浮在碘化罂粟油脂肪酸乙酯中的亲脂性铂络合物的制备可用作治疗顺铂耐药性癌症的药剂。
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公开(公告)号：US07284716B2
公开(公告)日：2007-10-23
申请号：US10513440
申请日：2003-06-05
申请人： Mitsuru Nakano , Shoji Fukushima , Hisashi Kimura
发明人： Mitsuru Nakano , Shoji Fukushima , Hisashi Kimura
IPC分类号： B02C23/36
CPC分类号： B01F3/1221 , B01F3/08 , B01F3/0807 , B01F7/00141 , B01F7/00241 , B01F7/00908 , B01F7/164 , B01F2003/125
摘要： Disclosed is an agitating device (3) to be disposed in a batch-type vessel or the like. The agitating device (3) has an upper cover plate (5), a bottom cover plate (6), an impeller (7), an inner screen member (8), and first and second outer screen members (9, 10). When a mixed liquid including a dispersoid and a dispersion medium passes through liquid communication holes (19) of the inner screen member (8) and liquid communication holes (22, 25) of the outer screen members (9, 10) during the course where it flows outward from the impeller (7) to get out of an interplate space, the circumferential component of the flow vector of the mixed liquid is mostly eliminated to allow the mixed liquid to have substantially only the radial component. This prevents the generation of vortexes so as to apply a sufficiently high shearing force to the mixed liquid to effectively prevent the formation of macro bubbles in the mixed liquid.
摘要翻译： 公开了一种设置在间歇式容器等中的搅拌装置（3）。 搅拌装置（3）具有上盖板（5），底盖板（6），叶轮（7），内筛部件（8）以及第一和第二外筛部件（9,10）。 当包含分散质和分散介质的混合液通过内筛部件（8）的液体连通孔（19）和外筛部件（9,10）的液体连通孔（22,25）时，其中 它从叶轮（7）向外流出以离开板间空间，混合液体的流动向量的圆周分量大部分被消除，以使混合液体基本上仅具有径向分量。 这防止产生涡流，从而对混合液施加足够高的剪切力，以有效地防止在混合液体中形成大气泡。
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公开(公告)号：US07253209B2
公开(公告)日：2007-08-07
申请号：US10344239
申请日：2001-08-08
IPC分类号： A61K31/282
CPC分类号： A61K9/0019 , A61K9/08 , A61K9/10 , A61K31/282 , A61K47/14 , A61K47/24 , A61K47/44
摘要： Preparation of a lipophilic platinum complex being dissolved or suspended in an iodized poppyseed oil fatty acid ethyl ester is useful as an agent for treatment of cisplatin-resistant cancers.
摘要翻译： 溶解或悬浮在碘化罂粟油脂肪酸乙酯中的亲脂性铂络合物的制备可用作治疗顺铂耐药性癌症的药剂。
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公开(公告)号：US4828518A
公开(公告)日：1989-05-09
申请号：US54397
申请日：1987-05-26
申请人： Masatoshi Kouda , Hiroshi Takeshita , Katsumi Yonekura , Noboru Tohge , Hiroyuki Hashimoto , Shoji Fukushima , Sadao Asanabe , Kunio Saki , Susumu Matsumoto , Takao Sasajima
发明人： Masatoshi Kouda , Hiroshi Takeshita , Katsumi Yonekura , Noboru Tohge , Hiroyuki Hashimoto , Shoji Fukushima , Sadao Asanabe , Kunio Saki , Susumu Matsumoto , Takao Sasajima
IPC分类号： B63H5/10
CPC分类号： B63H5/10
摘要： A double reverse revolution propeller apparatus includes front and rear propeller wherein the rear propeller is rotated at higher speeds than the front propeller. When seizure occurs, an inner shaft is disconnected from an engine at an inner shaft connection unit and is connected to an outer shaft at an inner and outer shaft connection unit to be driven in the same direction as the outer shaft. The ratio of absorption horsepower of the front propeller to the rear propeller can to be substantially equal to the ratio of rotational speed of the front propeller to that of the rear propeller. One or both of the front and rear propeller can include a variable pitch propeller. The front propeller can have more blades than the rear propeller.
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公开(公告)号：US20060264502A1
公开(公告)日：2006-11-23
申请号：US11495709
申请日：2006-07-31
IPC分类号： A61K31/282
CPC分类号： A61K9/0019 , A61K9/08 , A61K9/10 , A61K31/282 , A61K47/14 , A61K47/24 , A61K47/44
摘要： Preparation of a lipophilic platinum complex being dissolved or suspended in an iodized poppyseed oil fatty acid ethyl ester is useful as an agent for treatment of cisplatin-resistant cancers.
摘要翻译： 溶解或悬浮在碘化罂粟油脂肪酸乙酯中的亲脂性铂络合物的制备可用作治疗顺铂耐药性癌症的药剂。
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7.发明授权
公开(公告)号：US5637309A
公开(公告)日：1997-06-10
申请号：US309152
申请日：1994-09-20
申请人： Masahiro Tajima , Takashi Yoshimoto , Shoji Fukushima , Toshihiko Kaminuma , Ritsuko Ehama , Takaaki Baba , Kazuo Watabe
发明人： Masahiro Tajima , Takashi Yoshimoto , Shoji Fukushima , Toshihiko Kaminuma , Ritsuko Ehama , Takaaki Baba , Kazuo Watabe
CPC分类号： C07K14/43577 , A61K38/225 , A61K9/2013 , A61K9/2027 , A61K9/205 , A61K9/2054 , A61K38/00 , Y10S514/808 , Y10S514/929
摘要： A prolonged releasing pharmaceutical preparation is provided carrying a physiologically active substance, particularly, calcitonin gene-related peptide (CGRP) or a maxadilan (MAX). This pharmaceutical preparation can attain the expected effects by incorporating the physiologically active substance into a combination, as carriers for the physiologically active substance, of a cellulosic polymer and at least one auxiliary component selected from the group consisting of fats and oils, waxes, fatty acids, saccharides and polyacrylate ester derivatives. The pharmaceutical preparation can conveniently be used, in living bodies, particularly as an intrathecal implantation-type preparation.
摘要翻译： 提供延长释放的药物制剂，其携带生理活性物质，特别是降钙素基因相关肽（CGRP）或maxadilan（MAX）。 这种药物制剂可以通过将生理活性物质并入作为生理活性物质的载体的纤维素聚合物和至少一种选自脂肪和油，蜡，脂肪酸的辅助成分的组合来实现预期的效果 ，糖和聚丙烯酸酯衍生物。 药物制剂可以方便地用于生物体中，特别是鞘内注射型制剂。
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8.发明授权Method and apparatus for fusing together the bottom of tubular container formed of synthetic resin 失效将由合成树脂形成的管状容器的底部熔合在一起的方法和装置
公开(公告)号：US4681645A
公开(公告)日：1987-07-21
申请号：US762820
申请日：1985-08-05
CPC分类号： B65B51/225 , B29C65/08 , B29C65/081 , B29C66/1122 , B29C66/43123 , B29C66/7373 , B29C66/80 , B29C66/81419 , B29C66/81433 , B29C66/8167 , B29C66/8324 , B29C66/73921 , B29L2023/20 , Y10T156/14
摘要： A method for fusing together the bottom of a charged tubular container, formed of a synthetic resin, with its mouth being turned down, comprising the steps of:engaging a flattened portion of the upper end of said tubular container with one side of a vibrator terminal provided at the lower end of an ultrasonic generator oscillating at a given angle to said flattened portion, andapplying ultrasonic vibrations on said one side of said terminal, thereby applying said ultrasonic vibrations on said flattened portion.
摘要翻译： 一种将由合成树脂形成的带电管状容器的底部的底部熔合在一起的方法，其端口向下翻转，包括以下步骤：将所述管状容器的上端的平坦部分与振动器端子的一侧接合 设置在与所述平坦部分以给定角度振荡的超声波发生器的下端，并且在所述端子的所述一侧上施加超声波振动，从而在所述平坦部分上施加所述超声波振动。
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公开(公告)号：US07761014B2
公开(公告)日：2010-07-20
申请号：US11694832
申请日：2007-03-30
申请人： Shoji Fukushima
发明人： Shoji Fukushima
IPC分类号： G03G15/00
CPC分类号： G03G15/553 , G03G15/0863 , G03G15/556 , G03G2215/0697 , G03G2221/1823
摘要： An image forming apparatus includes: plural cartridges; a storage unit provided in the respective cartridges; and a writing unit that writes data into the storage unit. The writing unit writes data on usage statuses of one cartridge and the other cartridges into one storage unit provided in the one cartridge.
摘要翻译： 图像形成装置包括：多个盒; 设置在各个盒中的存储单元; 以及将数据写入存储单元的写入单元。 写入单元将一个盒和其他盒的使用状态的数据写入设置在一个盒中的一个存储单元中。
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公开(公告)号：US20050242218A1
公开(公告)日：2005-11-03
申请号：US10513440
申请日：2003-06-05
申请人： Mitsuru Nakano , Shoji Fukushima , Hisashi Kimura
发明人： Mitsuru Nakano , Shoji Fukushima , Hisashi Kimura
CPC分类号： B01F3/1221 , B01F3/08 , B01F3/0807 , B01F7/00141 , B01F7/00241 , B01F7/00908 , B01F7/164 , B01F2003/125
摘要： Disclosed is an agitating device (3) to be disposed in a batch-type vessel or the like. The agitating device (3) has an upper cover plate (5), a bottom cover plate (6), an impeller (7), an inner screen member (8), and first and second outer screen members (9, 10). When a mixed liquid including a dispersoid and a dispersion medium passes through liquid communication holes (19) of the inner screen member (8) and liquid communication holes (22, 25) of the outer screen members (9, 10) during the course where it flows outward from the impeller (7) to get out of an interplate space, the circumferential component of the flow vector of the mixed liquid is mostly eliminated to allow the mixed liquid to have substantially only the radial component. This prevents the generation of vortexes so as to apply a sufficiently high shearing force to the mixed liquid to effectively prevent the formation of macro bubbles in the mixed liquid.
摘要翻译： 公开了一种设置在间歇式容器等中的搅拌装置（3）。 搅拌装置（3）具有上盖板（5），底盖板（6），叶轮（7），内筛部件（8）以及第一和第二外筛部件（9,10）。 当包含分散质和分散介质的混合液通过内筛部件（8）的液体连通孔（19）和外筛部件（9,10）的液体连通孔（22,25）时，其中 它从叶轮（7）向外流出以离开板间空间，混合液体的流动向量的圆周分量大部分被消除，以使混合液体基本上仅具有径向分量。 这防止产生涡流，从而对混合液施加足够高的剪切力，以有效地防止在混合液体中形成大气泡。
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