HEPATITIS C VIRUS INHIBITORS
    8.
    发明申请
    HEPATITIS C VIRUS INHIBITORS 有权
    HEPATITIS C病毒抑制剂

    公开(公告)号:US20090234102A1

    公开(公告)日:2009-09-17

    申请号:US12241868

    申请日:2008-09-30

    IPC分类号: C07K16/18 C07H21/02

    摘要: The present invention aims to provide hepatitis C virus inhibitors capable of inhibiting viral replication in hepatitis C virus-infected cells.The replication of hepatitis C virus can be inhibited and hepatitis C virus-infected cells can be specifically injured by specifically inhibiting BGT-1 or AKR1C1 involved in the replication of hepatitis C virus. Thus, viral inhibitors comprising a substance inhibiting BGT-1 or AKR1C1 are effective for the treatment of hepatitis C.

    摘要翻译: 本发明旨在提供能够抑制丙型肝炎病毒感染细胞中病毒复制的丙型肝炎病毒抑制剂。 可以抑制丙型肝炎病毒的复制,通过特异性抑制丙型肝炎病毒复制中的BGT-1或AKR1C1可以特异性地损伤丙型肝炎病毒感染的细胞。 因此,包含抑制BGT-1或AKR1C1的物质的病毒抑制剂对于治疗丙型肝炎是有效的。