公开(公告)号：US20150141263A1

公开(公告)日：2015-05-21

申请号：US14411628

申请日：2013-06-28

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Kuan-Ta Lu ,  Allen Cheng

IPC: C12N15/10 ,  C12Q1/68

CPC classification number: C12N15/1065 ,  C12N15/1027 ,  C12N15/1079 ,  C12N15/66 ,  C12Q1/6869 ,  G01N2035/00752 ,  C12Q2525/131 ,  C12Q2563/179

Abstract: The invention relates to methods and compositions that enable the rapid generation of high-order combinations of genetic elements, and that provide a barcoded basis for rapid characterization of the specific combination of genetic elements encoded within a single cell or in a pooled population.

Abstract translation: 本发明涉及能够快速产生遗传元件的高阶组合的方法和组合物，并且提供了用于快速表征在单个细胞或合并的群体内编码的遗传元件的特定组合的条形码基础的方法和组合物。

公开(公告)号：US09315806B2

公开(公告)日：2016-04-19

申请号：US14411628

申请日：2013-06-28

Applicant: Massachusetts Institute of Technology

Inventor： Timothy Kuan-Ta Lu ,  Allen Cheng

IPC: C12N15/70 ,  C12N15/10 ,  C12Q1/68 ,  G01N35/00

CPC classification number: C12N15/1065 ,  C12N15/1027 ,  C12N15/1079 ,  C12N15/66 ,  C12Q1/6869 ,  G01N2035/00752 ,  C12Q2525/131 ,  C12Q2563/179

Abstract: The invention relates to methods and compositions that enable the rapid generation of high-order combinations of genetic elements, and that provide a barcoded basis for rapid characterization of the specific combination of genetic elements encoded within a single cell or in a pooled population.

Abstract translation: 本发明涉及能够快速产生遗传元件的高阶组合的方法和组合物，并且提供了用于快速表征在单个细胞或合并的群体内编码的遗传元件的特定组合的条形码基础的方法和组合物。