公开(公告)号：US20190093073A1

公开(公告)日：2019-03-28

申请号：US16141107

申请日：2018-09-25

Applicant: Massachusetts Institute of Technology

Inventor： Armon R Sharei ,  Andrea Adamo ,  Robert S. Langer ,  Klavs F. Jensen

IPC: C12N5/071 ,  C12M1/42 ,  C12M3/06 ,  C12N15/87 ,  B82Y5/00

Abstract: A microfluidic system for causing perturbations in a cell membrane, the system including a microfluidic channel defining a lumen and being configured such that a cell suspended in a buffer can pass therethrough, wherein the microfluidic channel includes a cell-deforming constriction, wherein a diameter of the constriction is a function of the diameter of the cell.