公开(公告)号：US20090173302A1

公开(公告)日：2009-07-09

申请号：US11949875

申请日：2007-12-04

Applicant: Matthew Evans ,  Florin Bugescu

Inventor： Matthew Evans ,  Florin Bugescu

IPC: F01L1/14

CPC classification number: F01L13/0005 ,  F01L1/146 ,  F01L2001/256 ,  F01L2105/00 ,  Y10T74/2107

Abstract: A switchable double tappet (1) is provided, especially for a tappet-push rod valve train of an internal combustion engine, with a cylindrical housing (2), which is arranged so that it oscillates via its outer casing (3) in a guide (4) in the internal combustion engine side and which has a bore (5) on the camshaft side, in which an inner element (6) moves axially relative to this borehole, wherein, on one side, a cam contact surface (10) is intrinsic to this inner element on its end projecting past an edge (7) of the borehole (5) or lower head (9) running in the region of the edge (7) and also, on the other side, at least one coupling slide (11) is intrinsic in its interior in the decoupled case, and this coupling slide can be displaced partially for a coupled case in or under a respective catch surface (12) of the housing (2), wherein between an upper head (13) of the inner element (6) facing away from the lower head (9) and a lower side (14) of a crossbar (15) of the housing (2), at least one lost-motion spring (16) is tensioned and, in a borehole (17) of the housing (2) away from the camshaft, above the crossbar (15), there are two supports (18) lying next to one another, on each of which an end of a tappet push rod can be supported.

Abstract translation: 提供了一种可切换双挺杆（1），特别是用于内燃机的挺杆推杆气门机构，其具有圆柱形壳体（2），其被布置成使得其经由其外壳（3）在导向件 （4），并且其中内部元件（6）相对于该钻孔轴向移动，其中在一侧具有凸轮接触表面（10）的凸轮轴侧上具有孔（5）的内燃机侧， 该内部元件在其端部上固有地突出穿过在边缘（7）的区域中延伸的钻孔（5）或下部头部（9）的边缘（7），并且在另一侧上至少一个联接 滑动件（11）在解耦壳体的内部是固有的，并且该联接滑块可以部分地移动到壳体（2）的相应的接合表面（12）内或下方的联接壳体，其中在上部头部（13） ）离开所述下部头部（9）的内部元件（6）和所述壳体（2）的横杆（15）的下侧（14），在l 东一个失速弹簧（16）被张紧，并且在外壳（2）的钻孔（17）中远离凸轮轴，在横杆（15）上方有两个彼此相邻的支撑件（18） 在其中每个可以支撑挺杆推杆的端部。

公开(公告)号：US07201125B2

公开(公告)日：2007-04-10

申请号：US11466157

申请日：2006-08-22

Applicant: Matthew Evans ,  William Dammers ,  Florin Bugescu

Inventor： Matthew Evans ,  William Dammers ,  Florin Bugescu

IPC: F01L1/18

CPC classification number: F01L13/0036 ,  F01L1/08 ,  F01L1/18 ,  F01L1/185 ,  F01L2105/00 ,  Y10T74/2107

Abstract: A valve train for an internal combustion engine is provided, with the valve train having a switchable rocker arm assembly (1) with a plurality of rocker arms (6, 7, 8) for activating at least one gas exchange valve (2), and also having at least one camshaft (3) with differently contoured cams (4, 5) through which different adjusting displacements can be imparted to individual rocker arms of the rocker arm assembly (1). The assembly further includes a switching device (9) for selectively activating the rocker arms for driving the gas exchange valve (2) with a varying valve lift. To create a valve train in which individual gas exchange valves can be operated in different modes of operation with only a small amount of construction work and expense, the rocker arm assembly (1) has a stationary rocker arm shaft (10) on which at least two outer rocker arms (6, 7), that are in continuous contact with associated, differently contoured cams (4, 5), and a center rocker arm (8) with a lever arm extension (11) through which the gas exchange valve (2), in operative connection to one of the two outer rocker arms (6, 7), can be selectively actuated, are mounted for tilting movement. Actuatable locking pins (12, 13) are arranged on the outer rocker arms (6, 7) for sliding axially parallel to the rocker arm shaft (10), a locking pin receiver (14) is arranged on the center rocker arm (8) and positioning aids (15, 16, 17) are arranged on the outer and the center rocker arms (6, 7, 8), so that the center rocker arm (8) can be selectively force-locked to one of the two outer rocker arms (6, 7) or be deactivated.

Abstract translation: 提供一种用于内燃机的气门机构，其中气门机构具有可转换的摇臂组件（1），其具有用于致动至少一个气体交换阀（2）的多个摇臂（6,7,8），以及 还具有具有不同轮廓的凸轮（4,5）的至少一个凸轮轴（3），通过该凸轮轴可以向摇臂组件（1）的各个摇臂提供不同的调节位移。 组件还包括用于选择性地启动摇臂以用于改变气门升程来驱动气体交换阀（2）的开关装置（9）。 为了创建一个气门机构，其中单独的气体交换阀可以以不同的施工作业和费用在不同的操作模式下操作，摇臂组件（1）具有固定的摇臂轴（10），至少 与相关联的不同轮廓的凸轮（4,5）连续接触的两个外摇臂（6,7）以及具有杠杆臂延伸部（11）的中心摇臂（8），气体交换阀 可操作地连接到两个外摇臂（6,7）中的一个，可以选择性地致动，安装成用于倾斜运动。 可动止动销（12,13）设置在外摇臂（6,7）上，用于沿轴向平行于摇臂轴（10）滑动，锁定销接收器（14）设置在中心摇臂（8）上， 并且定位辅助装置（15,16,17）设置在外部和中心摇臂（6,7,8）上，使得中心摇臂（8）可以选择性地强制锁定到两个外摇臂 手臂（6,7）或停用。

公开(公告)号：US07637237B2

公开(公告)日：2009-12-29

申请号：US11949875

申请日：2007-12-04

Applicant: Matthew Evans ,  Florin Bugescu

Inventor： Matthew Evans ,  Florin Bugescu

IPC: F01L1/14

CPC classification number: F01L13/0005 ,  F01L1/146 ,  F01L2001/256 ,  F01L2105/00 ,  Y10T74/2107

Abstract: A switchable double tappet (1) is provided, especially for a tappet-push rod valve train of an internal combustion engine, with a cylindrical housing (2), which is arranged so that it oscillates via its outer casing (3) in a guide (4) in the internal combustion engine side and which has a bore (5) on the camshaft side, in which an inner element (6) moves axially relative to this borehole, wherein, on one side, a cam contact surface (10) is intrinsic to this inner element on its end projecting past an edge (7) of the borehole (5) or lower head (9) running in the region of the edge (7) and also, on the other side, at least one coupling slide (11) is intrinsic in its interior in the decoupled case, and this coupling slide can be displaced partially for a coupled case in or under a respective catch surface (12) of the housing (2), wherein between an upper head (13) of the inner element (6) facing away from the lower head (9) and a lower side (14) of a crossbar (15) of the housing (2), at least one lost-motion spring (16) is tensioned and, in a borehole (17) of the housing (2) away from the camshaft, above the crossbar (15), there are two supports (18) lying next to one another, on each of which an end of a tappet push rod can be supported.

Abstract translation: 提供了一种可切换双挺杆（1），特别是用于具有圆柱形壳体（2）的内燃机的挺杆推杆气门机构，其布置成使得其经由其外壳（3）在导向件 （4），并且其中内部元件（6）相对于该钻孔轴向移动，其中在一侧具有凸轮接触表面（10）的凸轮轴侧上具有孔（5）的内燃机侧， 该内部元件在其端部上固有地突出穿过在边缘（7）的区域中延伸的钻孔（5）或下头（9）的边缘（7），并且在另一侧上至少一个联接 滑动件（11）在解耦壳体的内部是固有的，并且该联接滑块可以部分地移动到壳体（2）的相应的接合表面（12）内或下方的联接壳体，其中在上部头部（13） ）离开所述下部头部（9）的内部元件（6）和所述壳体（2）的横杆（15）的下侧（14），在l 东一个失速弹簧（16）被张紧，并且在外壳（2）的钻孔（17）中远离凸轮轴，在横杆（15）上方有两个彼此相邻的支撑件（18） 在其中每个可以支撑挺杆推杆的端部。

公开(公告)号：US20070039578A1

公开(公告)日：2007-02-22

申请号：US11466157

申请日：2006-08-22

Applicant: Matthew Evans ,  William Dammers ,  Florin Bugescu

Inventor： Matthew Evans ,  William Dammers ,  Florin Bugescu

IPC: F01L1/34 ,  F01L1/02

CPC classification number: F01L13/0036 ,  F01L1/08 ,  F01L1/18 ,  F01L1/185 ,  F01L2105/00 ,  Y10T74/2107

Abstract: A valve train for an internal combustion engine is provided, with the valve train having a switchable rocker arm assembly (1) with a plurality of rocker arms (6, 7, 8) for activating at least one gas exchange valve (2), and also having at least one camshaft (3) with differently contoured cams (4, 5) through which different adjusting displacements can be imparted to individual rocker arms of the rocker arm assembly (1). The assembly further includes a switching device (9) for selectively activating the rocker arms for driving the gas exchange valve (2) with a varying valve lift. To create a valve train in which individual gas exchange valves can be operated in different modes of operation with only a small amount of construction work and expense, the rocker arm assembly (1) has a stationary rocker arm shaft (10) on which at least two outer rocker arms (6, 7), that are in continuous contact with associated, differently contoured cams (4, 5), and a center rocker arm (8) with a lever arm extension (11) through which the gas exchange valve (2), in operative connection to one of the two outer rocker arms (6, 7), can be selectively actuated, are mounted for tilting movement. Actuatable locking pins (12, 13) are arranged on the outer rocker arms (6, 7) for sliding axially parallel to the rocker arm shaft (10), a locking pin receiver (14) is arranged on the center rocker arm (8) and positioning aids (15, 16, 17) are arranged on the outer and the center rocker arms (6, 7, 8), so that the center rocker arm (8) can be selectively force-locked to one of the two outer rocker arms (6, 7) or be deactivated.

Abstract translation: 提供一种用于内燃机的气门机构，其中气门机构具有可转换的摇臂组件（1），其具有用于致动至少一个气体交换阀（2）的多个摇臂（6,7,8），以及 还具有具有不同轮廓的凸轮（4,5）的至少一个凸轮轴（3），通过该凸轮轴可以向摇臂组件（1）的各个摇臂提供不同的调节位移。 组件还包括用于选择性地启动摇臂以用于改变气门升程来驱动气体交换阀（2）的开关装置（9）。 为了创建一个气门机构，其中单独的气体交换阀可以以不同的施工作业和费用在不同的操作模式下操作，摇臂组件（1）具有固定的摇臂轴（10），至少 与相关联的不同轮廓的凸轮（4,5）连续接触的两个外摇臂（6,7）以及具有杠杆臂延伸部（11）的中心摇臂（8），气体交换阀 可操作地连接到两个外摇臂（6,7）中的一个，可以选择性地致动，安装成用于倾斜运动。 可动止动销（12,13）设置在外摇臂（6,7）上，用于沿轴向平行于摇臂轴（10）滑动，锁定销接收器（14）设置在中心摇臂（8）上， 并且定位辅助装置（15,16,17）设置在外部和中心摇臂（6,7,8）上，使得中心摇臂（8）可以选择性地强制锁定到两个外摇臂 手臂（6,7）或停用。

公开(公告)号：US08940960B2

公开(公告)日：2015-01-27

申请号：US13122339

申请日：2009-10-01

Applicant: Alexander Ploss ,  Matthew Evans ,  Charles Rice

Inventor： Alexander Ploss ,  Matthew Evans ,  Charles Rice

IPC: C12N15/90 ,  C12N15/63

CPC classification number: G01N33/5008 ,  C07K14/705 ,  C12N2740/16043 ,  C12N2770/24211 ,  G01N33/502 ,  G01N2333/186 ,  G01N2500/00

Abstract: The human Occludin protein is identified as an essential Hepatitis C Virus (HCV) cell entry factor. Occludin is shown to render murine and other non-human cells infectable with HCV and to be required for HCV-susceptibility of human cells. Associated methods for inhibiting HCV infection, transgenic animal models for HCV pathogenesis, methods of identifying compounds or agents that prevent or mitigate interaction of HCV with Occludin, and HCV inhibitory agents are also disclosed. Kits and cell culture compositions useful for identifying compounds or agents that prevent or mitigate interaction of HCV with Occludin are also provided.

Abstract translation: 人类Occludin蛋白被鉴定为必需的丙型肝炎病毒（HCV）细胞进入因子。 闭合素显示使鼠和其他非人类细胞能够感染HCV，并且需要人类细胞的HCV敏感性。 还公开了用于抑制HCV感染的相关方法，用于HCV发病机理的转基因动物模型，鉴定预防或减轻HCV与Occludin的相互作用的化合物或药剂的方法以及HCV抑制剂。 还提供了可用于鉴定预防或减轻HCV与Occludin相互作用的化合物或试剂的试剂盒和细胞培养组合物。

公开(公告)号：US20110271356A1

公开(公告)日：2011-11-03

申请号：US13122339

申请日：2009-10-01

Applicant: Alexander Ploss ,  Matthew Evans ,  Charles Rice

Inventor： Alexander Ploss ,  Matthew Evans ,  Charles Rice

IPC: A01K67/00 ,  A61K31/7088 ,  A61P31/14 ,  C40B30/00 ,  G01N33/566 ,  C12Q1/68 ,  A61K39/395 ,  A61K38/02

CPC classification number: G01N33/5008 ,  C07K14/705 ,  C12N2740/16043 ,  C12N2770/24211 ,  G01N33/502 ,  G01N2333/186 ,  G01N2500/00

Abstract: The human Occludin protein is identified as an essential Hepatitis C Virus (HCV) cell entry factor. Occludin is shown to render murine and other non-human cells infectable with HCV and to be required for HCV—susceptibility of human cells. Associated methods for inhibiting HCV infection, transgenic animal models for HCV pathogenesis, methods of identifying compounds or agents that prevent or mitigate interaction of HCV with Occludin, and HCV inhibitory agents are also disclosed. Kits and cell culture compositions useful for identifying compounds or agents that prevent or mitigate interaction of HCV with Occludin are also provided.

Abstract translation: 人类Occludin蛋白被鉴定为必需的丙型肝炎病毒（HCV）细胞进入因子。 闭合素显示使鼠和其他非人类细胞能够感染HCV，并且需要人类细胞的HCV敏感性。 还公开了用于抑制HCV感染的相关方法，用于HCV发病机理的转基因动物模型，鉴定预防或减轻HCV与Occludin的相互作用的化合物或药剂的方法以及HCV抑制剂。 还提供了可用于鉴定预防或减轻HCV与Occludin相互作用的化合物或试剂的试剂盒和细胞培养组合物。

公开(公告)号：US07246587B2

公开(公告)日：2007-07-24

申请号：US11480157

申请日：2006-06-30

Applicant: Matthew Evans ,  Peter Sailer

Inventor： Matthew Evans ,  Peter Sailer

IPC: F01L1/14

CPC classification number: F01L13/0005 ,  F01L1/146 ,  F01L13/0031 ,  F01L2105/00

Abstract: The invention proposes a deactivating element (1) for a valve train of an internal combustion engine. The deactivating element (1) comprises a housing (2) and an inner element (4) that is axially displaceable in the bore (3) of the housing (2). According to the invention, the pistons (7) arranged in the inner element (4) for coupling into an annular groove (12) in the housing (2) possess two flattened regions (10, 15) arranged diametrically opposite each other in axial direction of the deactivating element (1). The height of the annular groove (12) is reduced by a measure of a height of the second, additional flattened region (15). Due to the reduction of height of the annular groove (12), its volume is also reduced. This results in advantages activation and deactivation times.

公开(公告)号：US20070000459A1

公开(公告)日：2007-01-04

申请号：US11480157

申请日：2006-06-30

Applicant: Matthew Evans ,  Peter Sailer

Inventor： Matthew Evans ,  Peter Sailer

IPC: F01L1/14

CPC classification number: F01L13/0005 ,  F01L1/146 ,  F01L13/0031 ,  F01L2105/00

Abstract: The invention proposes a deactivating element (1) for a valve train of an internal combustion engine. The deactivating element (1) comprises a housing (2) and an inner element (4) that is axially displaceable in the bore (3) of the housing (2). According to the invention, the pistons (7) arranged in the inner element (4) for coupling into an annular groove (12) in the housing (2) possess two flattened regions (10, 15) arranged diametrically opposite each other in axial direction of the deactivating element (1). The height of the annular groove (12) is reduced by a measure of a height of the second, additional flattened region (15). Due to the reduction of height of the annular groove (12), its volume is also reduced. This results in advantages activation and deactivation times.

Abstract translation: 本发明提出了一种用于内燃机的气门机构的停用元件（1）。 所述失活元件（1）包括壳体（2）和可在所述壳体（2）的所述孔（3）中轴向移动的内部元件）。 根据本发明，布置在内部元件（4）中用于联接到壳体（2）中的环形槽（12）中的活塞（7）具有两个在轴向方向上彼此径向相对布置的扁平区域（10,15） 的去激活元件（1）。 通过测量第二附加平坦化区域（15）的高度来减小环形槽（12）的高度。 由于环形槽（12）的高度减小，其体积也减小。 这导致了激活和停用时间的优势。

公开(公告)号：USD532379S1

公开(公告)日：2006-11-21

申请号：US29195495

申请日：2003-12-11

Applicant: Gregory Sorrentino ,  Matthew Evans

Designer： Gregory Sorrentino ,  Matthew Evans

公开(公告)号：US20060225682A1

公开(公告)日：2006-10-12

申请号：US11375348

申请日：2006-03-14

Applicant: Matthew Evans ,  Jermel Jones ,  Peter Sailer ,  Oliver Schnell ,  Tim Hosenfeldt

Inventor： Matthew Evans ,  Jermel Jones ,  Peter Sailer ,  Oliver Schnell ,  Tim Hosenfeldt

IPC: F01L1/14

CPC classification number: C23C14/025 ,  C23C14/0605 ,  F01L1/14 ,  F01L1/146 ,  F01L1/16 ,  F01L13/0005 ,  F01L13/0036 ,  F01L2001/256 ,  F01L2101/00 ,  F01L2103/00 ,  F01L2105/00 ,  F01L2107/00 ,  F01L2800/02 ,  F01L2820/01 ,  Y10T74/2107

Abstract: A switchable valve-drive component (1) for variable transmission of a stroke generated by one or more cam projections to a gas-exchange valve of an internal combustion engine is provided. The valve-drive component (1) has transmission elements (3, 4), which can be connected with a positive fit by coupling elements (8) in the transmission direction, in which force transmission surface sections (16) of the coupling elements (8) can be clamped between force transmission surface sections (20) of the transmission elements (3, 4). Here, at least one of the force transmission surface sections (16, 20) should be provided with a wear protection layer (23). This layer comprises at least one metal-free amorphous hydrocarbon layer with sp2-hybridized and sp3-hybridized carbon.

Abstract translation: 提供了一种用于将由一个或多个凸轮突起产生的冲程可变地传递到内燃机的气体交换阀的可切换阀驱动部件（1）。 所述阀驱动部件（1）具有传动元件（3,4），所述传动元件（3,4）可以通过所述传动方向上的联接元件（8）与所述连接元件（8）的力传递表面部分（16） 8）可以夹持在传动元件（3,4）的力传递表面部分（20）之间。 这里，力传递表面部分（16,20）中的至少一个应设置有磨损保护层（23）。 该层包含至少一个具有sp2-2杂化和sp3-3杂化碳的无金属无定形烃层。